A\u011f\u0131z i\u00e7i yaralar\u0131m\u0131z di\u011fer yaralar\u0131m\u0131za g\u00f6re daha h\u0131zl\u0131 ve etkin iyile\u015fir. Peki ama neden?<\/p>\n
FASEB B\u00fclteni\u2019nde\u00a0(http:\/\/www.faseb.org\/) yay\u0131mlanan yeni bir \u00e7al\u0131\u015fmada, a\u011f\u0131z i\u00e7i yaralar\u0131n, v\u00fccudun di\u011fer b\u00f6lgelerindekilere g\u00f6re neden daha h\u0131zl\u0131 ve etkin iyile\u015febildi\u011fi ara\u015ft\u0131r\u0131ld\u0131. \u015eimdiye kadar kapsaml\u0131 rol\u00fc tam anla\u015f\u0131lamasa da, t\u00fck\u00fcr\u00fc\u011f\u00fcn bu iyile\u015fmede etkili oldu\u011fu bilinmekteydi.Bu \u00e7al\u0131\u015fmada, kan damar\u0131 olu\u015fumu olarak bilinen angiogenesis s\u00fcrecine t\u00fck\u00fcr\u00fckte bulunan histatin -1 peptitinin etkisi incelendi. Bu peptit, yara iyile\u015fmesinde \u00f6nemli bir etkinli\u011fe sahipti. Ara\u015ft\u0131rmac\u0131lar, t\u0131pk\u0131 h\u00fccre g\u00f6\u00e7\u00fc ve ba\u011flanmas\u0131nda oldu\u011fu gibi histatin-1\u2019in, damar olu\u015fumunu da destekledi\u011fini g\u00f6sterdiler.<\/p>\n
\u015eili Santiago \u00dcniversitesi Di\u015f Hekimli\u011fi Fak\u00fcltesi\u2019nde \u00e7al\u0131\u015fmay\u0131 y\u00fcr\u00fctenlerden biri olan Vicente A. Torres\u2019e g\u00f6re, bulgular\u0131, a\u011f\u0131z yaralar\u0131yla deri yaralar\u0131 aras\u0131nda g\u00f6r\u00fclen iyile\u015fme farkl\u0131l\u0131klar\u0131n\u0131n alt\u0131nda yatan nedeni bulmak i\u00e7in yeni bir yol a\u00e7m\u0131\u015ft\u0131r. Bu sayede b\u00fcy\u00fck olas\u0131l\u0131kla a\u011f\u0131z d\u0131\u015f\u0131ndaki yara iyile\u015fmelerine daha do\u011fru bir tedavi yakla\u015f\u0131m\u0131 s\u00f6z konusu olabilecektir.<\/p>\n
Bu \u00e7al\u0131\u015fma 3 ortamda deneylenmi\u015ftir. 1) Kan damar\u0131 endoteli h\u00fccre k\u00fclt\u00fcr\u00fc, 2) hayvan modellemesi olarak tavuk embriyosu, 3) sa\u011fl\u0131kl\u0131 vericilerden al\u0131nan t\u00fck\u00fcr\u00fck \u00f6rnekleri. Bu \u00fc\u00e7 model kullan\u0131larak histatin-1 ve t\u00fck\u00fcr\u00fc\u011f\u00fcn kan damar\u0131 geli\u015fimini artt\u0131rd\u0131\u011f\u0131 belirlendi. Ara\u015ft\u0131rmac\u0131lar \u015fimdi bu bulgudan hareketle \u00e7al\u0131\u015fmay\u0131 geni\u015fletip, bu molek\u00fcl\u00fcn, \u00e7e\u015fitli materyallere ve implantlara dahil edilerek yara iyile\u015fmesine yard\u0131m etmesini hedefliyorlar.<\/p>\n
\u00c7al\u0131\u015fmay\u0131 yapan uzmanlardan Thoru Pederson\u2019a g\u00f6re elde edilen sonu\u00e7lar bizlere epey geni\u015f bir kap\u0131 a\u00e7m\u0131\u015ft\u0131r. Ayn\u0131 zamanda hayvanlar\u0131n ve zaman zaman \u00e7ocuklar\u0131n kendi yaralar\u0131n\u0131 neden yalad\u0131klar\u0131n\u0131 da anla\u015f\u0131l\u0131r k\u0131lmaktad\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"
A\u011f\u0131z i\u00e7i yaralar\u0131m\u0131z di\u011fer yaralar\u0131m\u0131za g\u00f6re daha h\u0131zl\u0131 ve etkin iyile\u015fir. Peki ama neden? FASEB B\u00fclteni\u2019nde\u00a0(http:\/\/www.faseb.org\/) yay\u0131mlanan yeni bir \u00e7al\u0131\u015fmada, a\u011f\u0131z i\u00e7i yaralar\u0131n, v\u00fccudun di\u011fer b\u00f6lgelerindekilere g\u00f6re neden daha h\u0131zl\u0131 ve etkin iyile\u015febildi\u011fi ara\u015ft\u0131r\u0131ld\u0131. \u015eimdiye kadar kapsaml\u0131 rol\u00fc tam anla\u015f\u0131lamasa da, t\u00fck\u00fcr\u00fc\u011f\u00fcn bu iyile\u015fmede etkili oldu\u011fu bilinmekteydi.Bu \u00e7al\u0131\u015fmada, kan damar\u0131 olu\u015fumu olarak bilinen angiogenesis s\u00fcrecine […]<\/p>\n","protected":false},"author":42,"featured_media":12818,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19,21],"tags":[197,1101,1102],"class_list":["post-12817","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","category-biyoloji","tag-biyoloji","tag-iyilesme","tag-yara"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/12817","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/users\/42"}],"replies":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=12817"}],"version-history":[{"count":0,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/12817\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media\/12818"}],"wp:attachment":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=12817"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=12817"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=12817"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}