Bristol \u00dcniversitesi T\u0131bbi Ara\u015ft\u0131rmalar Konseyi (Medical Research Council-MRC) B\u00fct\u00fcnc\u00fcl Epidemiyoloji B\u00f6l\u00fcm\u00fc\u2019nden biliminsanlar\u0131, d\u00fcnyan\u0131n \u00e7e\u015fitli yerlerindeki meslekta\u015flar\u0131yla birlikte, ROBO2 geni yak\u0131n\u0131ndaki genetik de\u011fi\u015fimlerle dil geli\u015fiminin erken evrelerinde \u00e7ocuklar\u0131n s\u00f6yleyebildi\u011fi kelime say\u0131lar\u0131 aras\u0131nda \u00f6nemli bir ba\u011flant\u0131 ke\u015ffettiler.<\/p>\n
Bizler 10-15 ayl\u0131kken kelimeleri s\u00f6ylemeye ba\u015flar\u0131z ve kelime hazinemiz bizimle birlikte b\u00fcy\u00fcr. 15-18 ayl\u0131kken 50, 18-30 ayl\u0131kken 200, alt\u0131 ya\u015f\u0131ndayken 14.000 civar\u0131nda kelime biliriz. Ortaokuldan ayr\u0131ld\u0131\u011f\u0131m\u0131zda ise da\u011farc\u0131\u011f\u0131m\u0131z 50.000\u2019in \u00fczerinde kelimeye sahiptir.<\/p>\n
Ara\u015ft\u0131rmac\u0131lar konu\u015fmay\u0131 \u00f6\u011frenmeyle genetik yap\u0131 aras\u0131ndaki ba\u011flant\u0131y\u0131, iki kelimeyi birle\u015ftirmeye ve daha karma\u015f\u0131k grametik yap\u0131lar\u0131 kurmaya ba\u015flamam\u0131\u015f, sadece birer kelimeyle ileti\u015fim kuran 15-18 ayl\u0131k \u00e7ocuklarda buldular.<\/p>\n
Nature Communications<\/i>\u2019da yay\u0131mlanan ara\u015ft\u0131rman\u0131n sonu\u00e7lar\u0131 yak\u0131n zaman \u00f6nce disleksi ve konu\u015fma bozukluklar\u0131yla ilgili ara\u015ft\u0131rmalarda incelenen \u201ckromozom 3\u201d \u00fczerindeki belirli genetik b\u00f6lgelere \u0131\u015f\u0131k tutuyor.<\/p>\n
ROBO2 geni, ROBO2 proteinini yapmak \u00fczere talimatlar ta\u015f\u0131r. Bu protein, bebeklerde dil geli\u015fimiyle birlikte ses \u00fcretimini de sa\u011flayan beyin h\u00fccreleri ve di\u011fer n\u00f6ronal h\u00fccre yap\u0131lanmalar\u0131ndaki kimyasallar\u0131 y\u00f6nlendirir. Ayn\u0131 zamanda ROBO2 proteini, okumayla ve konu\u015fma seslerinin depolanmas\u0131yla ba\u011flant\u0131l\u0131 oldu\u011fu bulunmu\u015f di\u011fer ROBO proteinleriyle s\u0131k s\u0131k etkile\u015fimde bulunur.<\/p>\n
Ara\u015ft\u0131rmay\u0131, MRC B\u00fct\u00fcnc\u00fcl Epidemiyoloji B\u00f6l\u00fcm\u00fc\u2019nden Profes\u00f6r Davey Smith ile ortakla\u015fa y\u00fcr\u00fcten Dr. Beate St. Pourcain, \u201cBu ara\u015ft\u0131rma, sa\u011fl\u0131kl\u0131 \u00e7ocuklarda dil geli\u015fiminin erken evrelerinde,\u00a0\u00f6zellikle sadece birer kelime ile konu\u015fulan d\u00f6nemde etkili olabilecek genetik fakt\u00f6rlerin daha iyi anla\u015f\u0131lmas\u0131na yard\u0131mc\u0131 oluyor ve ROBO proteini ile insanlardaki dilsel yeteneklerin \u00e7e\u015fitlili\u011fi aras\u0131ndaki ba\u011f\u0131 g\u00fc\u00e7lendiriyor\u201d diyor.<\/p>\n
Warwick \u00dcniversitesi\u2019nde g\u00f6rev yapan, \u00e7al\u0131\u015fman\u0131n ba\u015fyazarlar\u0131ndan Dr. Claire Haworth ise sonu\u00e7lar\u0131 \u015f\u00f6yle yorumluyor: \u201cBu ara\u015ft\u0131rmada DNA kullan\u0131larak elde edilen sonu\u00e7lar\u0131n, dil geli\u015fiminde genetik etkilerin \u00f6nemine ili\u015fkin yapt\u0131\u011f\u0131m\u0131z ikiz \u00e7al\u0131\u015fmalar\u0131n\u0131n sonu\u00e7lar\u0131n\u0131 do\u011frulad\u0131\u011f\u0131n\u0131 bulduk. Bu iyi bir haber; \u00e7\u00fcnk\u00fc dil geli\u015fiminin erken evrelerinde etkili olan pek \u00e7ok genetik fakt\u00f6r\u00fcn yakalanmas\u0131nda,\u00a0y\u00fcr\u00fct\u00fclmekte olan DNA bazl\u0131 ara\u015ft\u0131rmalar\u0131n\u00a0kullan\u0131labilece\u011fi anlam\u0131na geliyor.\u201d<\/p>\n
10.000\u2019i a\u015fk\u0131n \u00e7ocu\u011fun verilerinin kullan\u0131ld\u0131\u011f\u0131 ara\u015ft\u0131rma, Erken Genetik ve Ya\u015fam Seyri Epidemiyolojisi Birli\u011fi\u2019nde (EArly Genetics and Lifecourse Epidemiology Consortium; EAGLE) \u00e7al\u0131\u015fan biliminsanlar\u0131n\u0131n olu\u015fturdu\u011fu uluslararas\u0131 bir tak\u0131m taraf\u0131ndan yap\u0131ld\u0131.<\/p>\n","protected":false},"excerpt":{"rendered":"
Bristol \u00dcniversitesi T\u0131bbi Ara\u015ft\u0131rmalar Konseyi (Medical Research Council-MRC) B\u00fct\u00fcnc\u00fcl Epidemiyoloji B\u00f6l\u00fcm\u00fc\u2019nden biliminsanlar\u0131, d\u00fcnyan\u0131n \u00e7e\u015fitli yerlerindeki meslekta\u015flar\u0131yla birlikte, ROBO2 geni yak\u0131n\u0131ndaki genetik de\u011fi\u015fimlerle dil geli\u015fiminin erken evrelerinde \u00e7ocuklar\u0131n s\u00f6yleyebildi\u011fi kelime say\u0131lar\u0131 aras\u0131nda \u00f6nemli bir ba\u011flant\u0131 ke\u015ffettiler. Bizler 10-15 ayl\u0131kken kelimeleri s\u00f6ylemeye ba\u015flar\u0131z ve kelime hazinemiz bizimle birlikte b\u00fcy\u00fcr. 15-18 ayl\u0131kken 50, 18-30 ayl\u0131kken 200, alt\u0131 ya\u015f\u0131ndayken […]<\/p>\n","protected":false},"author":448,"featured_media":13276,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[165,19,214,231],"tags":[431,1192,494],"class_list":["post-132","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-128-sayi","category-bilim-gundemi","category-dilbilim","category-molekuler-biyoloji-ve-genetik","tag-gen","tag-konusma","tag-ogrenme"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/users\/448"}],"replies":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=132"}],"version-history":[{"count":0,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/132\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media\/13276"}],"wp:attachment":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}