Amerikan Ulusal Bilimler Akademisi\u2019nde (PNAS) yay\u0131mlanan makalede, uzun s\u00fcre marihuana kullanm\u0131\u015f ki\u015filerin beyin yap\u0131s\u0131 ve fonksiyonlar\u0131ndaki anormallikler, \u00e7e\u015fitli manyetik rezonans g\u00f6r\u00fcnt\u00fcleme (MRI) teknikleri ile ilk defa kapsaml\u0131 bir bi\u00e7imde g\u00f6sterildi. Sonu\u00e7lar, uzun s\u00fcreli marihuana kullan\u0131c\u0131lar\u0131nda, beynin ba\u011f\u0131ml\u0131l\u0131kla ili\u015fkili orbitofrontal korteks hacminde k\u00fc\u00e7\u00fclme oldu\u011funu ve bunun yan\u0131nda beyin i\u00e7i ba\u011flant\u0131lar\u0131n artt\u0131\u011f\u0131n\u0131 g\u00f6steriyor.<\/p>\n
Texas \u00dcniversitesi Beyin ve Davran\u0131\u015f Bilimleri B\u00f6l\u00fcm\u00fc\u2019nden Do\u00e7. Dr. Francesca Filbey, 2007\u2019den bu yana esrar kullan\u0131m oran\u0131n\u0131n s\u00fcrekli artt\u0131\u011f\u0131n\u0131 belirtiyor. Filbey\u2019e g\u00f6re, toplum sa\u011fl\u0131\u011f\u0131n\u0131 ilgilendiren bu konuyla ilgili \u00e7e\u015fitli g\u00f6r\u00fc\u015fmeler ve yasal d\u00fczenlemeler yap\u0131lm\u0131\u015f olsa da, esrar\u0131n uzun vadeli etkileriyle ilgili ara\u015ft\u0131rmalar yetersiz.<\/p>\n
Ara\u015ft\u0131rma ekibi, 48 yeti\u015fkin esrar kullan\u0131c\u0131s\u0131 ve esrar kullanmam\u0131\u015f 62 ki\u015fi \u00fczerinde \u00e7al\u0131\u015ft\u0131. Olas\u0131 tarafl\u0131l\u0131klar\u0131 engellemek i\u00e7in, ayn\u0131 ya\u015f, cinsiyet ve etnik k\u00f6kene sahip olacak \u015fekilde e\u015fle\u015ftirilen kat\u0131l\u0131mc\u0131lar\u0131n t\u00fct\u00fcn ve alkol kullan\u0131mlar\u0131 da ayr\u0131ca de\u011ferlendirildi. Ara\u015ft\u0131rmaya dahil olan esrar kullan\u0131c\u0131lar\u0131n\u0131n g\u00fcnde ortalama 3 defa esrar kulland\u0131klar\u0131 ortaya \u00e7\u0131kt\u0131. Bili\u015fsel testlerin sonu\u00e7lar\u0131na g\u00f6re esrar kullan\u0131c\u0131lar\u0131, ayn\u0131 ya\u015f ve cinsiyetteki kontrol grubuna g\u00f6re daha d\u00fc\u015f\u00fck IQ seviyelerine sahipti. Fakat bu farkl\u0131l\u0131\u011f\u0131n beyindeki anormalliklerle do\u011frudan ili\u015fkili oldu\u011fu s\u00f6ylenemez, \u00e7\u00fcnk\u00fc kat\u0131l\u0131mc\u0131lar\u0131n orbitofrontal korteks hacimleri ile IQ farklar\u0131 aras\u0131nda do\u011frudan bir ba\u011flant olmad\u0131\u011f\u0131 g\u00f6zlendi.<\/p>\n
MRI LLC \u015eirketi ve Texas \u00dcniversitesi\u2019nden Yard. Do\u00e7. Dr. Sina Aslan, bu \u00e7al\u0131\u015fmay\u0131 \u00f6zel k\u0131lan \u015feyin, \u00fc\u00e7 farkl\u0131 MRI tekni\u011fi kullan\u0131larak beynin de\u011fi\u015fik \u00f6zelliklerinin de\u011ferlendirilmesi oldu\u011funu s\u00f6yl\u00fcyor. Dr. Aslan\u2019a g\u00f6re sonu\u00e7lar, esrar kullan\u0131c\u0131lar\u0131nda beyindeki yap\u0131sal ve fonksiyonel ba\u011flant\u0131lar\u0131n artt\u0131\u011f\u0131n\u0131 g\u00f6steriyor. Bunun sebebi de, gri madde hacminde meydana gelen kayb\u0131 dengelemek olabilir. Ancak uzun vadeli kullan\u0131mda bu yap\u0131sal ba\u011flant\u0131lar da zarar g\u00f6rmeye ba\u015fl\u0131yor. Filbey\u2019e g\u00f6re bu \u00e7al\u0131\u015fma, her ne kadar beyinde ortaya \u00e7\u0131kan herhangi bir de\u011fi\u015fimin esrar kullan\u0131m\u0131n\u0131n do\u011frudan bir sonucu oldu\u011funu kan\u0131tlam\u0131yor olsa da, bu de\u011fi\u015fimlerin esrara ba\u015flama ya\u015f\u0131 ve kullan\u0131m s\u00fcresiyle ili\u015fkili oldu\u011funu destekliyor. Bu de\u011fi\u015fimlerin esrar kullan\u0131m\u0131 sona erince normale d\u00f6n\u00fcp d\u00f6nmedi\u011fi, arada bir kullanan ki\u015filer ve kronik kullan\u0131c\u0131larda benzer etkilerin g\u00f6r\u00fcl\u00fcp g\u00f6r\u00fclmedi\u011fi, esrar kullan\u0131m\u0131n\u0131n s\u00f6z konusu etkiler a\u00e7\u0131s\u0131ndan kesin bir sebep mi yoksa bir risk fakt\u00f6r\u00fc m\u00fc oldu\u011fu gibi sorular\u0131n yan\u0131tlar\u0131 i\u00e7in yeni ara\u015ft\u0131rmalara ihtiya\u00e7 var.<\/p>\n","protected":false},"excerpt":{"rendered":"
Amerikan Ulusal Bilimler Akademisi\u2019nde (PNAS) yay\u0131mlanan makalede, uzun s\u00fcre marihuana kullanm\u0131\u015f ki\u015filerin beyin yap\u0131s\u0131 ve fonksiyonlar\u0131ndaki anormallikler, \u00e7e\u015fitli manyetik rezonans g\u00f6r\u00fcnt\u00fcleme (MRI) teknikleri ile ilk defa kapsaml\u0131 bir bi\u00e7imde g\u00f6sterildi. Sonu\u00e7lar, uzun s\u00fcreli marihuana kullan\u0131c\u0131lar\u0131nda, beynin ba\u011f\u0131ml\u0131l\u0131kla ili\u015fkili orbitofrontal korteks hacminde k\u00fc\u00e7\u00fclme oldu\u011funu ve bunun yan\u0131nda beyin i\u00e7i ba\u011flant\u0131lar\u0131n artt\u0131\u011f\u0131n\u0131 g\u00f6steriyor. Texas \u00dcniversitesi Beyin ve […]<\/p>\n","protected":false},"author":847,"featured_media":12274,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[167,19,35,33],"tags":[254,2359,347,425],"class_list":["post-1451","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-130-sayi","category-bilim-gundemi","category-noroloji","category-saglik-bilimleri","tag-beyin","tag-esrar","tag-noroloji","tag-saglik"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/1451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/users\/847"}],"replies":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=1451"}],"version-history":[{"count":0,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/1451\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media\/12274"}],"wp:attachment":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=1451"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=1451"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=1451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}