\u0130nsan g\u00f6z\u00fcn\u00fcn en d\u0131\u015f katman\u0131 olan kornea, g\u00f6r\u00fcnt\u00fcy\u00fc odaklamak a\u00e7\u0131s\u0131ndan \u00e7ok \u00f6nemli bir role sahip.<\/p>\n
D\u00fcnya \u00e7ap\u0131nda, trahom ve bula\u015f\u0131c\u0131 g\u00f6z bozuklu\u011fu gibi hastal\u0131klar\u0131n sonucu olarak ortaya \u00e7\u0131kan kornea k\u00f6rl\u00fc\u011f\u00fcn\u00fc \u00f6nlemek i\u00e7in ameliyat olmay\u0131 bekleyen on milyon insan var. Buna kar\u015f\u0131n hen\u00fcz \u00e7ok s\u0131n\u0131rl\u0131 say\u0131da kornea nakil i\u00e7in uygun durumda.<\/p>\n
Buna ek olarak, yanma, yaralanma, kesilme, s\u0131yr\u0131lma veya \u00e7e\u015fitli hastal\u0131klar sonucu korneada olu\u015fan tahribatlar nedeniyle g\u00f6rme yetene\u011fini tamamen yitirmi\u015f yakla\u015f\u0131k be\u015f milyon insan daha var.<\/p>\n
Biyo-m\u00fcrekkep<\/strong><\/p>\n Experimental Eye Research<\/em>‘te yeni yay\u0131mlanan \u00e7al\u0131\u015fma, sa\u011fl\u0131kl\u0131 don\u00f6r korneadan al\u0131nan k\u00f6k h\u00fccrelerin alginat (deniz yosununda bulunan asidik bir tuz) ve kolajen (hayvanlardan elde edilen esneklik sa\u011flayan bir \u00e7e\u015fit protein) ile kar\u0131\u015ft\u0131r\u0131larak nas\u0131l sol\u00fcsyon, yani “biyo-m\u00fcrekkep” haz\u0131rland\u0131\u011f\u0131n\u0131 anlat\u0131yor.<\/p>\n Basit, d\u00fc\u015f\u00fck maliyetli bir \u00fc\u00e7 boyutlu biyo-yaz\u0131c\u0131 kullanarak, bu biyo-m\u00fcrekkep insan kornea \u015feklini olu\u015fturmak i\u00e7in e\u015fmerkezli \u00e7emberlere ba\u015far\u0131yla kal\u0131planm\u0131\u015f. Yazd\u0131rma i\u015flemi on dakikadan daha az s\u00fcrm\u00fc\u015f. K\u00f6k h\u00fccreler \u00fcreme veya ba\u015fka bir deyi\u015fle b\u00fcy\u00fcme g\u00f6stermi\u015f.<\/p>\n \u00c7al\u0131\u015fman\u0131n y\u00fcr\u00fct\u00fcc\u00fcs\u00fc, Newcastle \u00dcniversitesi Doku M\u00fchendisli\u011fi B\u00f6l\u00fcm\u00fc\u2019nde \u00f6\u011fretim \u00fcyesi olan Che Connon: “Alginat ve kolajenin bir kombinasyonu olan e\u015fsiz jellerimiz, malzemeyi \u00fcretirken k\u00f6k h\u00fccreleri canl\u0131 tutar. Jeller ayr\u0131ca \u00fcretilen malzeme \u015feklini koruyacak kadar sert, \u00fc\u00e7 boyutlu bir yaz\u0131c\u0131n\u0131n a\u011fz\u0131ndan s\u0131k\u0131lacak kadar da yumu\u015fak olmas\u0131n\u0131 sa\u011flar. Bu deney, benzer bir hidrojel i\u00e7inde oda s\u0131cakl\u0131\u011f\u0131nda haftalarca canl\u0131 tuttu\u011fumuz h\u00fccreler \u00fczerine olan bir \u00f6nceki \u00e7al\u0131\u015fmam\u0131z baz al\u0131narak kurguland\u0131. \u015eimdi, kullan\u0131c\u0131lar\u0131n k\u00f6k h\u00fccreleri ayr\u0131 ayr\u0131 yeti\u015ftirme zorlu\u011funu ortadan kald\u0131rarak dokular\u0131 basmaya ba\u015flamas\u0131na olanak tan\u0131yan bu biyo-m\u00fcrekkebi kullanmaya haz\u0131r\u0131z” diyor.<\/p>\n \u00c7al\u0131\u015fman\u0131n gelece\u011fi<\/strong><\/p>\n Ekipteki biliminsanlar\u0131 ayr\u0131ca, hastan\u0131n kendine has \u00f6zellikleri ile uyu\u015fan kornea da \u00fcretebileceklerini g\u00f6sterdiler.<\/p>\n Bas\u0131l\u0131 dokunun boyutlar\u0131n\u0131n belirlemesinde ger\u00e7ek kornea boyutlar\u0131 esas al\u0131nm\u0131\u015f. Hastan\u0131n g\u00f6z\u00fc taranarak boyut ve \u015fekil gibi elde edilen veriler ile uygun kornean\u0131n h\u0131zl\u0131 bir \u015fekilde bas\u0131labilmesi sa\u011flanabilir.<\/p>\n Connon \u015funu da ekliyor: “\u00dc\u00e7 boyutlu kornealar\u0131m\u0131z \u00fczerinde daha fazla test yapmam\u0131z ve nakil i\u00e7in kullanabilece\u011fimiz noktaya gelebilmemiz i\u00e7in muhtemelen birka\u00e7 y\u0131l ge\u00e7mesi gerekecek. Ancak g\u00f6sterdi\u011fimiz \u015fey, bir hastan\u0131n g\u00f6z\u00fcnden al\u0131nan koordinatlar\u0131 kullanarak kornea basman\u0131n ve bu yakla\u015f\u0131m\u0131n d\u00fcnya \u00e7ap\u0131nda kornea yetersizli\u011fi ile m\u00fccadele etme potansiyeline sahip oldu\u011fu.”<\/p>\n","protected":false},"excerpt":{"rendered":" \u0130lk \u00fc\u00e7 boyutlu insan korneas\u0131, \u0130ngiltere Newcastle \u00dcniversitesi\u2019ndeki biliminsanlar\u0131 taraf\u0131ndan \u00fc\u00e7 boyutlu yaz\u0131c\u0131lar kullan\u0131larak yazd\u0131r\u0131ld\u0131. Bu, gelecekte s\u0131n\u0131rs\u0131z say\u0131da kornea kayna\u011f\u0131n\u0131 garantilemek i\u00e7in bir teknik olarak kullan\u0131labilir. Milyonlarca insan\u0131n ihtiyac\u0131 \u0130nsan g\u00f6z\u00fcn\u00fcn en d\u0131\u015f katman\u0131 olan kornea, g\u00f6r\u00fcnt\u00fcy\u00fc odaklamak a\u00e7\u0131s\u0131ndan \u00e7ok \u00f6nemli bir role sahip. D\u00fcnya \u00e7ap\u0131nda, trahom ve bula\u015f\u0131c\u0131 g\u00f6z bozuklu\u011fu gibi hastal\u0131klar\u0131n sonucu […]<\/p>\n","protected":false},"author":812,"featured_media":26010,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19,21,33],"tags":[1986,3355,3356,425],"class_list":["post-26009","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","category-biyoloji","category-saglik-bilimleri","tag-goz","tag-kornea","tag-kornea-nakli","tag-saglik"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t![\"\"](\"https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2018\/05\/kornea-2.jpg\")