UBC n\u00f6rologlar\u0131n\u0131n yeni bir \u00e7al\u0131\u015fmas\u0131na g\u00f6re, genlerimiz \u00e7evremizdeki duygusal uyaranlara ne kadar duyarl\u0131 oldu\u011fumuzu etkiliyor olabilir. Journal of Neuroscience\u2019de yay\u0131mlanan yeni makalede, bir tip gen varyasyonu ta\u015f\u0131yan bireyler, pozitif ve negatif imajlar\u0131, beynin belli bir b\u00f6lgesinde g\u00f6sterilmek \u00fczere \u00e7ok daha \u201ccanl\u0131\u201d alg\u0131layabiliyor.<\/p>\n
UBC\u2019nin Psikoloji B\u00f6l\u00fcm\u00fc\u2019nden uzman Rebecca Todd\u2019a g\u00f6re, \u201cBu insanlar d\u00fcnyay\u0131 ger\u00e7ekten farkl\u0131 g\u00f6r\u00fcyor.\u201d S\u00f6z\u00fc edilen genetik farkl\u0131la\u015fmal\u0131 ki\u015filerde ise duygularla ba\u011flant\u0131l\u0131 olarak bu daha da g\u00f6ze \u00e7arpar hale geliyor.<\/p>\n
Norepinefrin hormonu, sinir h\u00fccrelerindeki sinyalleri kom\u015fu sinir h\u00fccresine ta\u015f\u0131yan kimyasallardan birdir (n\u00f6rotransmitter). Bu hormonun v\u00fccutta fazla salg\u0131lanmas\u0131, ki\u015finin k\u00f6t\u00fc an\u0131larla s\u00fcrekli bo\u011fu\u015fmas\u0131na sebep olmaktad\u0131r. ADRA2B geni ise kodlad\u0131\u011f\u0131 Alpha-2B adrenerjik resept\u00f6r ad\u0131ndaki ba\u015fka bir protein ile norepinefrinin bu k\u00f6t\u00fc etkisini normal d\u00fczeye indirir. ADRA2B geninin delesyonunda (gen kayb\u0131nda), norepinefrin hormonu v\u00fccutta artarak, ki\u015finin s\u00fcrekli k\u00f6t\u00fc an\u0131larla bo\u011fu\u015fmas\u0131na ve depresyona girmesine sebep olur. Todd\u2019un son \u00e7al\u0131\u015fmas\u0131, gen etkisiyle insan alg\u0131s\u0131n\u0131n \u00e7evresel etmenlerden nas\u0131l canl\u0131 bir \u015fekilde etkilendi\u011fini beyin g\u00f6r\u00fcnt\u00fcleme y\u00f6ntemiyle incelemesi a\u00e7\u0131s\u0131ndan bir ilktir. Ve sonu\u00e7lar \u015fa\u015f\u0131rt\u0131c\u0131 olmu\u015ftur.<\/p>\n
21\u2019i gen kay\u0131pl\u0131 39 g\u00f6n\u00fcll\u00fcde yap\u0131lan beyin g\u00f6r\u00fcnt\u00fclenmesinde ekip, delesyonlu ki\u015filerde beklediklerinden \u00e7ok daha fazla ve farkl\u0131 duygusal canl\u0131l\u0131k izlemi\u015flerdir. Gen varyasyonu ta\u015f\u0131yan g\u00f6n\u00fcll\u00fclerin beyinlerinin, \u00f6d\u00fcl-tehdit sisteminden ve dolay\u0131s\u0131yla duygusal dengelenmesinden sorumlu b\u00f6lgelerinde belirgin aktivite art\u0131\u015f\u0131 g\u00f6zlemlenmi\u015ftir. Todd\u2019a g\u00f6re bu, baz\u0131 bireylerin neden travma sonras\u0131 stres bozuklu\u011funa (PTSD) daha duyarl\u0131 olduklar\u0131n\u0131 ve s\u00fcrekli araya giren k\u00f6t\u00fc an\u0131larla u\u011fra\u015ft\u0131klar\u0131n\u0131 a\u00e7\u0131klayabilecektir.<\/p>\n
Duygular sadece d\u0131\u015f d\u00fcnyay\u0131 nas\u0131l hissetti\u011fimizle de\u011fil, beynimizin bu d\u00fcnyay\u0131 nas\u0131l alg\u0131lad\u0131\u011f\u0131na ba\u011fl\u0131 olarak \u015fekillenir. Cornell \u00dcniversitesi\u2019nde insan geli\u015fimi \u00fczerine \u00e7al\u0131\u015fan Prof. Adam Anderson\u2019a g\u00f6re, genlerin etkisiyle tam olarak \u201cpozitif\u201d ve \u201cnegatif\u201d a\u00e7\u0131dan d\u0131\u015f d\u00fcnyay\u0131 alg\u0131lad\u0131\u011f\u0131m\u0131zda, bu alg\u0131m\u0131z da \u201c\u00f6d\u00fcl\u201d ve\u201d tehdit\u201d olarak \u015fekillenebilecektir. Todd\u2019a g\u00f6re gen varyasyonunun baz\u0131 faydalar\u0131 mevcuttur. Varyasyonu ta\u015f\u0131yan bireyler, d\u0131\u015f d\u00fcnya de\u011fi\u015fikliklerini alg\u0131lamada ve buna g\u00f6re duygusal dengelemeyi sa\u011flamada, beyinlerinde adeta ek bir bilgisayar a\u011f\u0131ndan faydalanmaktalar.<\/p>\n
Todd\u2019a g\u00f6re buna verilecek en g\u00fczel \u00f6rnek, edebiyat d\u00fcnyas\u0131n\u0131n \u00fcnl\u00fc ismi Proust ve \u00fcnl\u00fc kurabiyeleridir. Malum, bunlar haf\u0131zan\u0131n kurabiyeleridir. Proust, annesinin g\u00f6nderdi\u011fi kurabiyenin ucunu \u00e7aya bat\u0131r\u0131r ve bu a\u011fz\u0131na de\u011fdi\u011fi anda bir anda \u00e7ocuklu\u011funa, teyzesinin odas\u0131na gitti\u011fini, teyzesinin de bir par\u00e7a madeleine\u2019i \u00e7aya bat\u0131r\u0131p onun a\u011fz\u0131na verdi\u011fi an\u0131 hat\u0131rlar, b\u00fct\u00fcn o k\u00f6y, b\u00fct\u00fcn bah\u00e7e, ev, \u00e7ocuklu\u011fu, \u00e7ay fincan\u0131ndan \u00e7\u0131kar ve odas\u0131na dolar. Mutluluk duygusu ruhuna dolar. Todd\u2019a g\u00f6re Proust kesinlikle bir varyant ta\u015f\u0131y\u0131c\u0131s\u0131d\u0131r!!<\/p>\n
\u00c7al\u0131\u015fmada g\u00f6n\u00fcll\u00fclerden \u201cses\u201d ya da belli imajlar\u0131n \u201cpozitif\u201d,\u201dnegatif\u201d veya \u201cn\u00f6tr\u201d olup olmad\u0131\u011f\u0131n\u0131 tahmin etmeleri istenmi\u015ftir. ADRA2b varyantl\u0131 g\u00f6n\u00fcll\u00fcler, artm\u0131\u015f duygusal canl\u0131l\u0131\u011f\u0131n etkisiyle, sesleri daha d\u00fc\u015f\u00fck seviyede alg\u0131larken (pozitif ve negatif imajlara ili\u015ftirilmi\u015f), n\u00f6tr imajlarda r\u00f6latif bir sonu\u00e7 ortaya \u00e7\u0131karm\u0131\u015flard\u0131r.<\/p>\n
Delesyon ta\u015f\u0131y\u0131c\u0131lar\u0131n\u0131n beynin duygusal y\u00f6nden hassasiyetten sorumlu kabul edilen belli b\u00f6lgelerinde belirgin \u015fekilde \u201ccanl\u0131\u201d aktiviteleri oldu\u011fu g\u00f6r\u00fcnt\u00fclenmi\u015ftir. ADRA2b varyasyonu \u00e7e\u015fitli etnik gruplarda farkl\u0131 d\u00fczeylerde a\u00e7\u0131\u011fa \u00e7\u0131kabilmektedir. Bu \u00e7al\u0131\u015fmada yard\u0131m\u0131na ba\u015fvurulan Kanadal\u0131 g\u00f6n\u00fcll\u00fclerin y\u00fczde 50\u2019si Kafkas k\u00f6kenliydi ve delesyonluydu, ancak di\u011fer etnik guruplarda da delesyon bildirilmi\u015ftir. \u00d6rne\u011fin bir \u00e7al\u0131\u015fmada y\u00fczde 10 oran\u0131nda Ruandal\u0131 ta\u015f\u0131y\u0131c\u0131 belirlenmi\u015ftir.<\/p>\n
Bundan sonra ki \u00e7al\u0131\u015fmalar, di\u011fer etnik guruplarda artm\u0131\u015f duygusal canl\u0131l\u0131\u011f\u0131 ortaya \u00e7\u0131karma ve ADRA2b\u2019nin kayg\u0131 bozuklu\u011fu, travma sonras\u0131 stres bozuklu\u011fu ve ba\u011f\u0131ml\u0131l\u0131k gibi sorunlarda nas\u0131l etkili olabilece\u011fini belirleme amac\u0131 i\u00e7erecektir<\/p>\n
Kaynaklar<\/strong><\/p>\n 1) http:\/\/www.sciencedaily.com\/releases\/2015\/05\/150507135919.htm UBC n\u00f6rologlar\u0131n\u0131n yeni bir \u00e7al\u0131\u015fmas\u0131na g\u00f6re, genlerimiz \u00e7evremizdeki duygusal uyaranlara ne kadar duyarl\u0131 oldu\u011fumuzu etkiliyor olabilir. Journal of Neuroscience\u2019de yay\u0131mlanan yeni makalede, bir tip gen varyasyonu ta\u015f\u0131yan bireyler, pozitif ve negatif imajlar\u0131, beynin belli bir b\u00f6lgesinde g\u00f6sterilmek \u00fczere \u00e7ok daha \u201ccanl\u0131\u201d alg\u0131layabiliyor. UBC\u2019nin Psikoloji B\u00f6l\u00fcm\u00fc\u2019nden uzman Rebecca Todd\u2019a g\u00f6re, \u201cBu insanlar d\u00fcnyay\u0131 ger\u00e7ekten farkl\u0131 g\u00f6r\u00fcyor.\u201d […]<\/p>\n","protected":false},"author":42,"featured_media":20301,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[173,19,231,35],"tags":[272,2187,292,347],"class_list":["post-2741","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-136-sayi","category-bilim-gundemi","category-molekuler-biyoloji-ve-genetik","category-noroloji","tag-dna","tag-duygular","tag-genetik","tag-noroloji"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/2741","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/users\/42"}],"replies":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=2741"}],"version-history":[{"count":0,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/2741\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media\/20301"}],"wp:attachment":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=2741"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=2741"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=2741"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n2) https:\/\/saltuerk.wordpress.com\/2011\/05\/12\/adra2b-geni-ve-kotu-anilarin-surekli-hatirlanmasi\/
\n3) http:\/\/atalet.blogspot.com.tr\/2011\/11\/frog-madeleine-mekik-proust-ve.html<\/p>\n","protected":false},"excerpt":{"rendered":"