Ba\u011f\u0131\u015f\u0131kl\u0131kta olduk\u00e7a \u00f6nemli bir yere sahip olan T h\u00fccreleri ya\u015fl\u0131 farelerde yeni sinir h\u00fccresi \u00fcretimini azaltabilir.<\/p>\n
Ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri; normalde faydal\u0131 olan h\u00fccrelerin hi\u00e7bir faydas\u0131 yokmu\u015f gibi g\u00f6r\u00fcnd\u00fc\u011f\u00fc durumlarda, ya\u015fl\u0131 farelerin beyinlerine zarar verebilir. 3 Temmuz\u2019da Nature dergisinde yay\u0131mlanan \u00e7al\u0131\u015fma \u00e7\u0131kt\u0131lar\u0131, ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerinin ya\u015flanmada rol oynayabilece\u011fi ihtimalini artt\u0131r\u0131yor.<\/p>\n
Stanford \u00dcniversitesi T\u0131p Fak\u00fcltesi’nden Anne Brunet ve \u00e7al\u0131\u015fma arkada\u015flar\u0131, fare beyinlerinde bulunan ve yeni sinir h\u00fccrelerinin do\u011fdu\u011fu subventrik\u00fcler b\u00f6lgedeki her t\u00fcrl\u00fc h\u00fccreyi tan\u0131mlamak i\u00e7in gen aktivitesi \u00fczerinde \u00e7al\u0131\u015ft\u0131. Gen\u00e7 farelere k\u0131yasla, ya\u015fl\u0131 farelerde o b\u00f6lgede daha fazla \u00f6ld\u00fcr\u00fcc\u00fc T h\u00fccresi vard\u0131. Nomalde ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin bu sava\u015f\u00e7\u0131lar\u0131, v\u00fccudun geri kalan k\u0131sm\u0131nda hasar g\u00f6rm\u00fc\u015f veya enfekte olmu\u015f h\u00fccreleri yok eder, ancak genellikle beyinde g\u00f6r\u00fclmesi beklenmez.<\/p>\n
\u00d6l\u00fcm sonras\u0131 insan beyni dokusu \u00fczerinde yap\u0131lan deneyler ya\u015fl\u0131 insanlarda da benzer bir durum oldu\u011funu g\u00f6sterdi. Ara\u015ft\u0131rmac\u0131lar, T h\u00fccrelerinin 79 ila 93 ya\u015f aral\u0131\u011f\u0131ndaki insanlar\u0131n dokular\u0131nda, 20 ila 44 ya\u015f aral\u0131\u011f\u0131ndaki insanlara g\u00f6re daha fazla bulundu\u011funu ke\u015ffetti.<\/p>\n
\u00d6ld\u00fcr\u00fcc\u00fc T h\u00fccreleri, farelerin beyinlerinde, interferon-gamma denilen bir bile\u015fik \u00fcretir. Bu molek\u00fcl, ya\u015fl\u0131l\u0131kla birlikte gelen yeni sinir h\u00fccrelerinin say\u0131ca azalmas\u0131ndan sorumlu olabilir.<\/p>\n
Bu sonu\u00e7lar, insan beyninin eri\u015fkin olarak yeni sinir h\u00fccreleri olu\u015fturmaya devam edip etmedi\u011fi konusunu yeniden g\u00fcndeme getirdi. E\u011fer devam ediyorsa; T h\u00fccrelerini beyinden ay\u0131ran tedaviler, ya\u015flanmayla gelen baz\u0131 zihinsel gerilemeleri engelleyebilecek bir yenileme olarak sinir h\u00fccresi \u00fcretiminin ya\u015fl\u0131l\u0131kta bile s\u00fcrmesine yard\u0131mc\u0131 olabilir.<\/p>\n
Kaynak:<\/strong> https:\/\/www.sciencenews.org\/article\/rogue-immune-cells-can-infiltrate-old-brains?tgt=nr<\/p>\n","protected":false},"excerpt":{"rendered":" Ba\u011f\u0131\u015f\u0131kl\u0131kta olduk\u00e7a \u00f6nemli bir yere sahip olan T h\u00fccreleri ya\u015fl\u0131 farelerde yeni sinir h\u00fccresi \u00fcretimini azaltabilir. Ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri; normalde faydal\u0131 olan h\u00fccrelerin hi\u00e7bir faydas\u0131 yokmu\u015f gibi g\u00f6r\u00fcnd\u00fc\u011f\u00fc durumlarda, ya\u015fl\u0131 farelerin beyinlerine zarar verebilir. 3 Temmuz\u2019da Nature dergisinde yay\u0131mlanan \u00e7al\u0131\u015fma \u00e7\u0131kt\u0131lar\u0131, ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerinin ya\u015flanmada rol oynayabilece\u011fi ihtimalini artt\u0131r\u0131yor. Stanford \u00dcniversitesi T\u0131p Fak\u00fcltesi’nden Anne Brunet ve \u00e7al\u0131\u015fma […]<\/p>\n","protected":false},"author":2049,"featured_media":35287,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[1194,4990,5018],"class_list":["post-35286","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-bagisiklik","tag-sinir-hucreleri","tag-t-hucreleri"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/35286","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/users\/2049"}],"replies":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=35286"}],"version-history":[{"count":0,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/35286\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media\/35287"}],"wp:attachment":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=35286"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=35286"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=35286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}