Psikiyatrik bozukluklarla ve v\u00fccudun \u015feker ve ya\u011f depolar\u0131n\u0131n kontrol\u00fcyle ba\u011flant\u0131l\u0131 olan genler, y\u0131k\u0131c\u0131 yeme bozuklu\u011funun geneti\u011fi \u00fczerine yap\u0131lan en geni\u015f ara\u015ft\u0131rmalarda, Anoreksiya’ya\u00a0 ba\u011fland\u0131.<\/p>\n
Anoreksiya, ruhsal bozukluklarda en y\u00fcksek \u00f6l\u00fcm oran\u0131na sahip olan hastal\u0131k. \u00c7al\u0131\u015fmada, Anoreksiya hastas\u0131 yakla\u015f\u0131k 17.000 Avrupal\u0131n\u0131n genomlar\u0131na bak\u0131ld\u0131. Hastalar\u0131n genetik yap\u0131lar\u0131, yeme bozuklu\u011fu olmayan 55.000\u2019den fazla ki\u015fiyle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131.<\/p>\n
Kuzey Karolina \u00dcniversitesi\u2019nden Cynthia Bulik\u2019in liderli\u011findeki ara\u015ft\u0131rmac\u0131lar, baz\u0131lar\u0131 beyinde ifade edilen 100\u2019den fazla genle ba\u011flant\u0131s\u0131 olan hastal\u0131kla ili\u015fkili sekiz genetik b\u00f6lge ke\u015ffettiler.<\/p>\n
Ara\u015ft\u0131rmac\u0131lar, b\u00f6ylesi bir b\u00f6lgenin; hipokamp\u00fcs\u00fcn, yemekle motive etme ve \u00f6d\u00fcllendirme de dahil olmak \u00fczere farelerin beslenme davran\u0131\u015flar\u0131nda b\u00fcy\u00fck rol oynad\u0131\u011f\u0131n\u0131 belirtiyorlar.<\/p>\n
Geni\u015f genetik veri taban\u0131, ara\u015ft\u0131rmac\u0131lar\u0131n, Anoreksiya’n\u0131n genetik i\u015faretini di\u011fer psikolojik bozukluklar\u0131n veya metabolik de\u011fi\u015fikliklerinkilerle \u00f6rt\u00fc\u015f\u00fcp \u00f6rt\u00fc\u015fmedi\u011fini test etmelerine izin verdi.<\/p>\n
Ba\u015fta k\u0131z \u00e7ocuklar\u0131 ve gen\u00e7 kad\u0131nlar olmak \u00fczere yakla\u015f\u0131k 200 ki\u015fiden birini etkileyen Anoreksiya’n\u0131n, obsesif kompulsif bozuklukla son derece ba\u011flant\u0131l\u0131 oldu\u011fu; depresyon, \u015fizofreni ve anksiyete ile daha az fakat \u00f6nemli ba\u011flant\u0131lar\u0131 oldu\u011fu fark edildi.<\/p>\n
Ayr\u0131ca ara\u015ft\u0131rmac\u0131lar, y\u0131llarca s\u00fcren e\u011fitim, \u00fcniversite bitirme ve hastal\u0131ktaki ortak \u00f6zellikle tutarl\u0131 olarak fiziksel aktivite d\u00fczeyleri aras\u0131nda olumlu bir ili\u015fki oldu\u011funu ke\u015ffettiler.<\/p>\n
Fakat ayn\u0131 zamanda v\u00fccudun a\u00e7l\u0131k ve kan \u015fekeri kontrol\u00fcn\u00fc i\u00e7eren en \u00f6nemli hormonlardan ikisiyle de ba\u011flant\u0131s\u0131 vard\u0131: Yemekten sonra tokluk hissini veren leptin ve \u015feker seviyelerini d\u00fc\u015f\u00fcren ins\u00fclin.<\/p>\n
\u00d6l\u00fcmc\u00fcl hastal\u0131k Ger\u00e7ekten de, Anoreksiya i\u00e7in \u00f6l\u00fcm oranlar\u0131 \u015fok edici. Neredeyse sadece kad\u0131nlarda g\u00f6r\u00fclen bu hastal\u0131k i\u00e7in \u00f6l\u00fcm oran\u0131 (\u00e7al\u0131\u015fmada yakla\u015f\u0131k 15.000 kad\u0131n ve sadece 447 erkek bulunuyordu) 20 y\u0131lda % 20.<\/p>\n Temel metabolik d\u00fczensizli\u011fin, yeme bozuklu\u011fu olan bireylerin sa\u011fl\u0131kl\u0131 bir v\u00fccut k\u00fctle indeksini (terap\u00f6tik olarak yeniledikten sonra bile) korumadaki zorlu\u011funu daha da artt\u0131rabilece\u011fi belirtiliyor.<\/p>\n Son olarak ara\u015ft\u0131rmac\u0131lar, \u201cSonu\u00e7lar\u0131m\u0131z, bu \u00f6l\u00fcmc\u00fcl hastal\u0131\u011f\u0131 tedavi etmek i\u00e7in yeni yollar aran\u0131rken, yeme bozuklu\u011fundaki hem metabolik hem de psikolojik etmenlerin dikkate al\u0131nmas\u0131 gerekti\u011fini g\u00f6steriyor\u201d diyorlar.<\/p>\n Kaynak<\/strong>:https:\/\/cosmosmagazine.com\/biology\/genetic-insight-into-anorexia-nervosa<\/p>\n","protected":false},"excerpt":{"rendered":" Psikiyatrik bozukluklarla ve v\u00fccudun \u015feker ve ya\u011f depolar\u0131n\u0131n kontrol\u00fcyle ba\u011flant\u0131l\u0131 olan genler, y\u0131k\u0131c\u0131 yeme bozuklu\u011funun geneti\u011fi \u00fczerine yap\u0131lan en geni\u015f ara\u015ft\u0131rmalarda, Anoreksiya’ya\u00a0 ba\u011fland\u0131. Anoreksiya, ruhsal bozukluklarda en y\u00fcksek \u00f6l\u00fcm oran\u0131na sahip olan hastal\u0131k. \u00c7al\u0131\u015fmada, Anoreksiya hastas\u0131 yakla\u015f\u0131k 17.000 Avrupal\u0131n\u0131n genomlar\u0131na bak\u0131ld\u0131. Hastalar\u0131n genetik yap\u0131lar\u0131, yeme bozuklu\u011fu olmayan 55.000\u2019den fazla ki\u015fiyle kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131. Kuzey Karolina \u00dcniversitesi\u2019nden Cynthia […]<\/p>\n","protected":false},"author":2049,"featured_media":35409,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[5051,292,5044],"class_list":["post-35408","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-anoreksiya","tag-genetik","tag-obsesif-kompulsif-bozukluk"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/35408","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/users\/2049"}],"replies":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=35408"}],"version-history":[{"count":0,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/35408\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media\/35409"}],"wp:attachment":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=35408"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=35408"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=35408"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n<\/strong>Bulgular, Anoreksiya’n\u0131n nas\u0131l tedavi edilece\u011fine dair yol haritas\u0131n\u0131 yeniden \u00e7izebilir.<\/p>\n