{"id":36099,"date":"2019-08-17T03:20:29","date_gmt":"2019-08-17T00:20:29","guid":{"rendered":"https:\/\/bilimvegelecek.com.tr\/?p=36099"},"modified":"2019-08-08T17:24:46","modified_gmt":"2019-08-08T14:24:46","slug":"yuksek-insulin-duzeyi-ile-pankreas-kanseri-arasinda-bir-baglanti-var","status":"publish","type":"post","link":"https:\/\/bilimvegelecek.com.tr\/index.php\/2019\/08\/17\/yuksek-insulin-duzeyi-ile-pankreas-kanseri-arasinda-bir-baglanti-var","title":{"rendered":"Y\u00fcksek ins\u00fclin d\u00fczeyi ile pankreas kanseri aras\u0131nda bir ba\u011flant\u0131 var!"},"content":{"rendered":"

British Kolombiya \u00dcniversitesi\u2019nde \u00e7al\u0131\u015fma y\u00fcr\u00fcten biliminsanlar\u0131 ilk defa, y\u00fcksek ins\u00fclin d\u00fczeyleri ile pankreas kanseri aras\u0131nda bir ba\u011flant\u0131 oldu\u011funu g\u00f6steren bir \u00e7al\u0131\u015fma yapt\u0131. 5 A\u011fustos g\u00fcn\u00fc Cell Matabolism\u2019de yay\u0131mlanan \u00e7al\u0131\u015fmada ara\u015ft\u0131rmac\u0131lar, pankreas kanseri olmaya yatk\u0131n farelerde hastal\u0131\u011f\u0131n geli\u015fmesinin \u00f6nlenip \u00f6nlenmeyece\u011fini g\u00f6zlemlemek i\u00e7in ins\u00fclin seviyelerini d\u00fc\u015f\u00fcr\u00fcld\u00fc. \u00c7al\u0131\u015fma ile birlikte ins\u00fclin seviyesinin d\u00fc\u015f\u00fcr\u00fclmesinin farelerde hastal\u0131k geli\u015fimini \u00f6nledi\u011fi g\u00f6zlendi. \u00c7al\u0131\u015fman\u0131n \u00e7\u0131kt\u0131lar\u0131, insanlarda pankreas kanserinin erken evrelerde te\u015fhis edilmesi ve kansere y\u00f6nelik \u00f6nlemler i\u00e7in umut vaat ediyor.<\/p>\n

Ara\u015ft\u0131rman\u0131n y\u00fcr\u00fct\u00fcc\u00fclerinden James Johnson, \u201cPankreas kanseri olduk\u00e7a ge\u00e7 a\u015famalarda fark edilebiliyor. Bu durum da onu, \u00f6l\u00fcmc\u00fcl kanser hastal\u0131klar\u0131ndan biri yap\u0131yor\u201d dedi ve ekledi: \u201cKanser hastal\u0131\u011f\u0131n\u0131n te\u015fhis edilmesinin ard\u0131ndan ge\u00e7en 5 y\u0131ll\u0131k s\u00fcre i\u00e7erisindeki sa\u011fkal\u0131m oranlar\u0131 y\u00fczde 5\u2019in alt\u0131nda. Ayr\u0131ca hastal\u0131\u011f\u0131n etkisi, obezite ile birlikte art\u0131\u015f g\u00f6steriyor.\u201d<\/p>\n

Bu noktada, v\u00fccudun kan \u015fekeri seviyesini kontrol alt\u0131nda tutmak i\u00e7in \u00fcretti\u011fi hormonlardan biri olan ins\u00fclinin haddinden fazla \u00fcretilmesi ile ortaya \u00e7\u0131kan “Hiperins\u00fclinemi” hastal\u0131\u011f\u0131na odaklanal\u0131m. Bu hastal\u0131k, obezite hastas\u0131 yeti\u015fkinlerin \u00fc\u00e7te birinde yayg\u0131n bir bi\u00e7imde g\u00f6r\u00fclen ve diyet ile ya\u015fam tarz\u0131 gibi fakt\u00f6rler taraf\u0131ndan d\u00fczenlenebilen bir hastal\u0131k olarak tan\u0131mlanmaktad\u0131r.<\/p>\n

\u00dcniversitenin H\u00fccresel ve Fizyolojik Bilimler b\u00f6l\u00fcm\u00fcnde \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcren Yard\u0131mc\u0131 Do\u00e7ent Jamel Kopp, \u201cHiperins\u00fclinemi ile pek \u00e7ok kanser t\u00fcr\u00fc aras\u0131nda bir ba\u011flant\u0131 oldu\u011fu ortaya \u00e7\u0131kt\u0131. Meme kanseri de dahil olmak \u00fczere pek \u00e7ok kanser ile aras\u0131ndaki ili\u015fki tan\u0131mland\u0131 ancak \u00f6zellikle de pankreas kanseri ile bu hastal\u0131k aras\u0131nda s\u0131k\u0131 bir ba\u011f oldu\u011fu ortaya \u00e7\u0131kar\u0131ld\u0131\u201d dedi ve ekledi: \u201cBu \u00e7al\u0131\u015fma, bu alana dair yap\u0131lm\u0131\u015f ilk \u00e7al\u0131\u015fma ve biz bu hipotezi test eden ilk ekibiz.\u201d<\/p>\n

\"\"
\u0130ns\u00fclin metabolizmas\u0131ndaki dengesizlik, d\u0131\u015far\u0131dan takviye ile d\u00fczenlenebiliyor<\/figcaption><\/figure>\n

\u00c7al\u0131\u015fman\u0131n y\u00fcr\u00fct\u00fcc\u00fclerinden doktora \u00f6\u011frencisi Anni Zhang, \u00e7al\u0131\u015fmaya ili\u015fkin olarak yapt\u0131\u011f\u0131 a\u00e7\u0131klamada “Pankreas kanseri geli\u015fmeye yatk\u0131n olan bir fare t\u00fcr\u00fc ile y\u00fcksek ins\u00fclin seviyelerine \u00e7\u0131kamayan bir fare t\u00fcr\u00fc se\u00e7ildi. Bu t\u00fcrlere ve kontrol farelerine bir y\u0131l boyunca, ins\u00fclin seviyesini artt\u0131ran ve pankreas kanserine yatk\u0131nl\u0131\u011f\u0131 art\u0131ran bir t\u00fcr diyet verildi. Bir y\u0131ll\u0131k \u00e7al\u0131\u015fman\u0131n sonucunda, d\u00fc\u015f\u00fck ins\u00fclin seviyesine sahip farelerin pankreas kanserinden korundu\u011fu ortaya \u00e7\u0131kar\u0131ld\u0131” dedi.<\/p>\n

Konuya ili\u015fkin a\u00e7\u0131klamalar\u0131na devam eden Johnson, \u201cD\u00fc\u015f\u00fck ins\u00fclin d\u00fczeyi, pankreasta kanserli h\u00fccre geli\u015fiminde azalmaya neden oldu\u201d dedi. Kopp ise, \u201cBunun di\u011fer kanser t\u00fcrleri i\u00e7in de ge\u00e7erli oldu\u011funu s\u00f6ylemekte bir s\u0131k\u0131nt\u0131 g\u00f6rm\u00fcyoruz\u201d a\u00e7\u0131klamalar\u0131nda bulundu ve ekledi: \u201c\u0130nsanlarda pankreas kanserinin y\u00fczde 90\u2019\u0131nda benzer mutasyonlar g\u00f6r\u00fclmektedir.\u201d<\/p>\n

\u0130ns\u00fclin d\u00fczeyi ile kanserle\u015fme aras\u0131ndaki ba\u011flant\u0131y\u0131 inceleyen biliminsanlar\u0131, bu noktada ileri bir ad\u0131m daha atma iste\u011fi i\u00e7indeler. \u015eimdi, ins\u00fclin d\u00fczeyi d\u00fc\u015f\u00fcr\u00fcld\u00fc\u011f\u00fcnde pankreas kanserinin daha sonraki a\u015famalar\u0131nda olumlu y\u00f6nde bir etki olup olmad\u0131\u011f\u0131n\u0131 ara\u015ft\u0131rmak istiyorlar.<\/p>\n

Kaynak:<\/strong> https:\/\/medicalxpress.com\/news\/2019-08-high-insulin-production-contribute-pancreatic.html<\/p>\n","protected":false},"excerpt":{"rendered":"

British Kolombiya \u00dcniversitesi\u2019nde \u00e7al\u0131\u015fma y\u00fcr\u00fcten biliminsanlar\u0131 ilk defa, y\u00fcksek ins\u00fclin d\u00fczeyleri ile pankreas kanseri aras\u0131nda bir ba\u011flant\u0131 oldu\u011funu g\u00f6steren bir \u00e7al\u0131\u015fma yapt\u0131. 5 A\u011fustos g\u00fcn\u00fc Cell Matabolism\u2019de yay\u0131mlanan \u00e7al\u0131\u015fmada ara\u015ft\u0131rmac\u0131lar, pankreas kanseri olmaya yatk\u0131n farelerde hastal\u0131\u011f\u0131n geli\u015fmesinin \u00f6nlenip \u00f6nlenmeyece\u011fini g\u00f6zlemlemek i\u00e7in ins\u00fclin seviyelerini d\u00fc\u015f\u00fcr\u00fcld\u00fc. \u00c7al\u0131\u015fma ile birlikte ins\u00fclin seviyesinin d\u00fc\u015f\u00fcr\u00fclmesinin farelerde hastal\u0131k geli\u015fimini \u00f6nledi\u011fi g\u00f6zlendi. […]<\/p>\n","protected":false},"author":1390,"featured_media":36103,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[4059,1499,2994,444,5193],"class_list":["post-36099","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-arastirma","tag-baglanti","tag-insulin","tag-kanser","tag-pankreas"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t