{"id":37545,"date":"2019-10-15T03:20:14","date_gmt":"2019-10-15T00:20:14","guid":{"rendered":"https:\/\/bilimvegelecek.com.tr\/?p=37545"},"modified":"2019-10-15T03:41:22","modified_gmt":"2019-10-15T00:41:22","slug":"bagisiklik-sistemi-hafizamizin-isleyisini-etkileyebilir-mi","status":"publish","type":"post","link":"https:\/\/bilimvegelecek.com.tr\/index.php\/2019\/10\/15\/bagisiklik-sistemi-hafizamizin-isleyisini-etkileyebilir-mi","title":{"rendered":"Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi, haf\u0131zam\u0131z\u0131n i\u015fleyi\u015fini etkileyebilir mi?"},"content":{"rendered":"<p>Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi, yabanc\u0131 maddelerin v\u00fccuda giri\u015fini \u00f6nler ve bir bi\u00e7imde v\u00fccuda giren bu maddelerin yok edilmesini sa\u011flar. Herhangi bir hastal\u0131k geli\u015fiminde de, hastal\u0131\u011f\u0131n olu\u015fumuna neden olan maddelerle sava\u015f\u0131r ve hastal\u0131\u011f\u0131n atlat\u0131lmas\u0131na yard\u0131m eder. Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi&#8217;ne ili\u015fkin yeni \u00e7al\u0131\u015fma, bu sistemin herhangi bir hastal\u0131k durumu s\u00f6z konusu olmad\u0131\u011f\u0131nda nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131na odakland\u0131. Bu durumda Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi, haf\u0131zan\u0131n i\u015fleyi\u015fini d\u00fczenlenmesine yard\u0131mc\u0131 oluyor. Ara\u015ft\u0131rma, Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi&#8217;nin haf\u0131zan\u0131n i\u015fleyi\u015fini d\u00fczenleyecek ve haf\u0131zan\u0131n g\u00fcc\u00fcn\u00fc artt\u0131racak bir t\u00fcr kimyasal mekanizma i\u015fleterek beyne yard\u0131mc\u0131 oldu\u011funu ortaya koydu.<\/p>\n<p>Portekiz&#8217;de bulunan Lizbon \u00dcniversitesi&#8217;nde \u00e7al\u0131\u015fma y\u00fcr\u00fcten Bruno Silva-Santos, insanlarda haf\u0131zan\u0131n geli\u015fimi konusuna e\u011fildiklerini ve Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi&#8217;nin sadece enfeksiyon ve t\u00fcm\u00f6rlerle sava\u015fan bir sistem oldu\u011funu s\u00f6yleyen geleneksel g\u00f6r\u00fc\u015f\u00fcn de\u011fi\u015febilece\u011fi sonucuna ula\u015ft\u0131klar\u0131n\u0131 ifade etti.<\/p>\n<figure id=\"attachment_37546\" aria-describedby=\"caption-attachment-37546\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-37546 size-medium\" src=\"https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2019\/10\/beyin-1-300x169.jpg\" alt=\"\" width=\"300\" height=\"169\" srcset=\"https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2019\/10\/beyin-1-300x169.jpg 300w, https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2019\/10\/beyin-1-768x432.jpg 768w, https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2019\/10\/beyin-1-600x338.jpg 600w, https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2019\/10\/beyin-1.jpg 800w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-37546\" class=\"wp-caption-text\">Deneysel \u00e7al\u0131\u015fmalar, IL-17 molek\u00fcl\u00fcn\u00fcn haf\u0131za \u00fczerinde etkili oldu\u011funu g\u00f6steriyor.<\/figcaption><\/figure>\n<p>Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi\u2019nin \u00e7e\u015fitli yan rollere sahip oldu\u011fu bilinmekteydi ancak yeni \u00e7al\u0131\u015fmayla ula\u015f\u0131lan sonu\u00e7lar, bu sistemin haf\u0131zaya etkilerini ortaya \u00e7\u0131kard\u0131. \u00c7al\u0131\u015fma ekibinden Julie Ribot, hastal\u0131k etmeni ile sava\u015fan beyaz kan h\u00fccrelerini (akyuvar\/l\u00f6kosit) ta\u015f\u0131yan damarlar\u0131n menenj ad\u0131 verilen beyin zar\u0131nda bulundu\u011funu s\u00f6yl\u00fcyor. Ribot a\u00e7\u0131klamalar\u0131na devam ederek, \u201cBu ger\u00e7ekten olduk\u00e7a \u00f6nemli. \u00c7\u00fcnk\u00fc bu durum, beyin ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemimizin hasta olmad\u0131\u011f\u0131m\u0131z zamanlarda bile s\u00fcrekli ileti\u015fim halinde oldu\u011funu g\u00f6steriyor\u201d dedi.<\/p>\n<p>Beyin ile ba\u011f\u0131\u015f\u0131kl\u0131k sistemi aras\u0131ndaki ili\u015fkinin varl\u0131\u011f\u0131, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi h\u00fccrelerinden T lenfositlerinin \u00f6\u011frenme ve davran\u0131\u015flarda anahtar \u00f6neme sahip oldu\u011funu g\u00f6steren son \u00e7al\u0131\u015fmalarla ortaya konmu\u015ftu. Ancak ekip bu \u00e7al\u0131\u015fmalar\u0131n \u00f6tesinde bir ba\u011flant\u0131 aray\u0131\u015f\u0131na girdi. Beyin zar\u0131na yerle\u015fmi\u015f olan T lenfosit h\u00fccrelerinin haf\u0131za i\u00e7in \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcnen biliminsanlar\u0131, bu durumun analiz edilmesi i\u00e7in \u00e7e\u015fitli deney d\u00fczenekleri geli\u015ftirdiler. Deneyler sonucunda buradaki bili\u015fsel durumla ilgili olan molek\u00fcl\u00fc ke\u015ffettiler. Bu molek\u00fcl, iltihaplanma \u00f6nleyici \u00f6zelli\u011fi ile ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n sa\u011flanmas\u0131nda \u00f6nemli bir role sahip olan IL-17 molek\u00fcl\u00fcd\u00fcr. Deneysel \u00e7al\u0131\u015fmalar, bu molek\u00fcl\u00fcn, beynin haf\u0131za merkezi olan hipokamp\u00fcsteki beyin h\u00fccrelerinde \u00fcretkenli\u011fi artt\u0131ran bir tetikleyici g\u00f6revi g\u00f6rd\u00fc\u011f\u00fcn\u00fc ortaya koymu\u015ftur.<\/p>\n<p>Science Immunology dergisinde yay\u0131nlanan \u00e7al\u0131\u015fman\u0131n y\u00fcr\u00fct\u00fcc\u00fclerinden Silva-Santos, bu \u00f6nemli molek\u00fcl\u00fcn v\u00fccudu al\u0131m\u0131n\u0131n \u00f6nemini vurgularken, vitaminlerin bu s\u00fcrecin i\u015fleyi\u015finde etkili oldu\u011funun alt\u0131n\u0131 \u00e7iziyor.<\/p>\n<p><strong>Kaynak:<\/strong> https:\/\/cosmosmagazine.com\/biology\/immune-system-lends-a-hand-to-the-brain<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi, yabanc\u0131 maddelerin v\u00fccuda giri\u015fini \u00f6nler ve bir bi\u00e7imde v\u00fccuda giren bu maddelerin yok edilmesini sa\u011flar. Herhangi bir hastal\u0131k geli\u015fiminde de, hastal\u0131\u011f\u0131n olu\u015fumuna neden olan maddelerle sava\u015f\u0131r ve hastal\u0131\u011f\u0131n atlat\u0131lmas\u0131na yard\u0131m eder. Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi&#8217;ne ili\u015fkin yeni \u00e7al\u0131\u015fma, bu sistemin herhangi bir hastal\u0131k durumu s\u00f6z konusu olmad\u0131\u011f\u0131nda nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131na odakland\u0131. Bu durumda Ba\u011f\u0131\u015f\u0131kl\u0131k Sistemi, haf\u0131zan\u0131n [&hellip;]<\/p>\n","protected":false},"author":1390,"featured_media":37547,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[2413,254,1875,298,2660],"class_list":["post-37545","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-bagisiklik-sistemi","tag-beyin","tag-enfeksiyon","tag-hafiza","tag-tumor"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/37545","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1390"}],"replies":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=37545"}],"version-history":[{"count":0,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/37545\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media\/37547"}],"wp:attachment":[{"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=37545"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=37545"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bilimvegelecek.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=37545"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}