{"id":38941,"date":"2019-12-11T03:25:45","date_gmt":"2019-12-11T00:25:45","guid":{"rendered":"https:\/\/bilimvegelecek.com.tr\/?p=38941"},"modified":"2019-12-10T16:06:47","modified_gmt":"2019-12-10T13:06:47","slug":"alzheimer-hastaligi-ile-iliskili-olan-bir-protein-kesfedildi","status":"publish","type":"post","link":"https:\/\/bilimvegelecek.com.tr\/index.php\/2019\/12\/11\/alzheimer-hastaligi-ile-iliskili-olan-bir-protein-kesfedildi","title":{"rendered":"Alzheimer’\u0131 \u00f6nlemek i\u00e7in yeni bir umut"},"content":{"rendered":"

Biliminsanlar\u0131n\u0131n yeni ara\u015ft\u0131rmas\u0131, CD33 adl\u0131 proteinin insan beynindeki ilgili b\u00f6lgenin d\u00fczenlenmesiyle Alzheimer hastal\u0131\u011f\u0131na kar\u015f\u0131 m\u00fccadelede kullan\u0131labilecek bir ara\u00e7 olabilece\u011fini ortaya koydu.<\/p>\n

Ara\u015ft\u0131rma, bu proteini bir ki\u015finin Alzheimer hastal\u0131\u011f\u0131 olas\u0131l\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcrebilecek bir fakt\u00f6r olarak tan\u0131mlayan daha \u00f6nceki ara\u015ft\u0131rmalara dayan\u0131yor. Ancak insan populasyonunun yakla\u015f\u0131k y\u00fczde 10\u2019u bu proteinin tersine i\u015fleyen bir ba\u015fka proteine sahip.<\/p>\n

Bu ara\u015ft\u0131rman\u0131n y\u00fcr\u00fct\u00fcc\u00fclerinden olan kimyager Matthew Macauley, \u201cBeyinde bulunan mikroglia ismi verilen h\u00fccreler, Alzheimer hastal\u0131\u011f\u0131nda kritik bir rol oynar. Koruyucu da, zararl\u0131 da olabilirler\u201d a\u00e7\u0131klamalar\u0131nda bulundu. \u00c7al\u0131\u015fmaya kat\u0131lan biliminsalar\u0131ndan biri olan Abhishek Bhattacherjee ise, “CD33\u2019\u00fcn mikroglia h\u00fccreleri \u00fczerindeki etkisiyle birlikte Alzheimer hastal\u0131\u011f\u0131ndan korunmak m\u00fcmk\u00fcn\u201d dedi.<\/p>\n

Macauley, \u201c\u00c7al\u0131\u015fman\u0131n bulgular\u0131 CD33 ile Alzheimer hastal\u0131\u011f\u0131 aras\u0131ndaki nedensel ili\u015fkinin test edilmesinin yan\u0131 s\u0131ra CD33 proteini ile mikroglia h\u00fccreleri aras\u0131ndaki ili\u015fkinin anla\u015f\u0131lmas\u0131 i\u00e7in de yeni bir basamak sa\u011fl\u0131yor\u201d a\u00e7\u0131klamalar\u0131nda bulundu ve ekledi: \u201cMikroglia h\u00fccreleri, fagositoz ad\u0131 verilen i\u015flemi yapabilme yetene\u011fine sahiptir. Bu i\u015flem ile Alzheimer hastal\u0131\u011f\u0131na neden olan n\u00f6rodejeneratif plaklarda temizleme yap\u0131labilir. B\u00f6ylece bu hastal\u0131k i\u00e7in \u00f6nleyici veya tedavi edici yeni metotlar geli\u015ftirilebilir.\u201d<\/p>\n

Kaynak:<\/strong> https:\/\/medicalxpress.com\/news\/2019-12-protein-brain-alzheimer-disease.html<\/p>\n","protected":false},"excerpt":{"rendered":"

Biliminsanlar\u0131n\u0131n yeni ara\u015ft\u0131rmas\u0131, CD33 adl\u0131 proteinin insan beynindeki ilgili b\u00f6lgenin d\u00fczenlenmesiyle Alzheimer hastal\u0131\u011f\u0131na kar\u015f\u0131 m\u00fccadelede kullan\u0131labilecek bir ara\u00e7 olabilece\u011fini ortaya koydu. Ara\u015ft\u0131rma, bu proteini bir ki\u015finin Alzheimer hastal\u0131\u011f\u0131 olas\u0131l\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcrebilecek bir fakt\u00f6r olarak tan\u0131mlayan daha \u00f6nceki ara\u015ft\u0131rmalara dayan\u0131yor. Ancak insan populasyonunun yakla\u015f\u0131k y\u00fczde 10\u2019u bu proteinin tersine i\u015fleyen bir ba\u015fka proteine sahip. Bu ara\u015ft\u0131rman\u0131n y\u00fcr\u00fct\u00fcc\u00fclerinden […]<\/p>\n","protected":false},"author":1390,"featured_media":38942,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[982,254,5656,1171],"class_list":["post-38941","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-alzheimer","tag-beyin","tag-mikroglia-hucreleri","tag-protein"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t