{"id":39643,"date":"2020-01-09T13:26:53","date_gmt":"2020-01-09T10:26:53","guid":{"rendered":"https:\/\/bilimvegelecek.com.tr\/?p=39643"},"modified":"2020-01-09T13:26:53","modified_gmt":"2020-01-09T10:26:53","slug":"2600-yillik-insan-beyni-gunumuze-kadar-nasil-korundu","status":"publish","type":"post","link":"https:\/\/bilimvegelecek.com.tr\/index.php\/2020\/01\/09\/2600-yillik-insan-beyni-gunumuze-kadar-nasil-korundu","title":{"rendered":"2600 y\u0131ll\u0131k insan beyni g\u00fcn\u00fcm\u00fcze kadar nas\u0131l korundu?"},"content":{"rendered":"

Binlerce y\u0131l \u00f6nce, \u015fimdilerde \u0130ngiltere’de bir k\u00f6y olan Heslington b\u00f6lgesinde bir insan\u0131n cesedi \u00e7evre \u015fartlar\u0131n\u0131n etkisiyle par\u00e7alanmaya ba\u015flad\u0131. Bu par\u00e7alanma s\u0131ras\u0131nda organlar\u0131 \u00e7amurla\u015ft\u0131, sa\u00e7\u0131 toza d\u00f6n\u00fc\u015ft\u00fc. Sonunda, kemikleri ve beyninin k\u00fc\u00e7\u00fck bir par\u00e7as\u0131 kald\u0131. Kemiklerinin g\u00fcn\u00fcm\u00fcze kadar korunarak aktar\u0131lmas\u0131 ola\u011fand\u0131. Ancak beyin par\u00e7as\u0131n\u0131n g\u00fcn\u00fcm\u00fcze kadar darbe almadan ve par\u00e7alanmadan gelmesi s\u0131ra d\u0131\u015f\u0131 bir durumdu. Biliminsanlar\u0131 bu s\u0131ra d\u0131\u015f\u0131 durumu, beyin dokusu \u00fczerinde yapt\u0131klar\u0131 \u00e7al\u0131\u015fmayla birlikte daha iyi anlamam\u0131za yard\u0131mc\u0131 oldu.<\/p>\n

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Kaz\u0131 \u00e7al\u0131\u015fmas\u0131nda elde edilen kafatas\u0131 ve beyin yap\u0131s\u0131.<\/figcaption><\/figure>\n

2008 y\u0131l\u0131nda \u0130ngiltere’de ke\u015ffedilen bu beyin yap\u0131s\u0131, en eski insan sinir dokusu \u00f6rneklerinden biri ve ayn\u0131 zamanda \u00e7\u00f6z\u00fcm\u00fc zor bilmeceleri de ta\u015f\u0131yor. Tipik bir \u00f6l\u00fcmde beyin dokusu ayr\u0131\u015fmaya ba\u015flar. Di\u011fer organlarla ve v\u00fccut par\u00e7alar\u0131 ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda bu ayr\u0131\u015fma b\u00fcy\u00fck bir h\u0131za sahiptir. \u00c7e\u015fitli proteinler h\u00fccresel alt yap\u0131y\u0131 y\u0131kmak i\u00e7in \u00e7al\u0131\u015facak ve \u00e7\u00fcr\u00fcme ba\u015flayacakt\u0131r. Biliminsanlar\u0131 \u00e7\u00fcr\u00fcmeye kar\u015f\u0131 koruma \u00f6zelli\u011fi kazanan bu \u00f6rnekteki beyin dokusu \u00fczerinde \u00e7al\u0131\u015fmalar yaparak bu koruma \u00f6zelli\u011finin nas\u0131l geli\u015fti\u011fini inceledi. Koruma \u00f6zelli\u011finin iyi anla\u015f\u0131lmas\u0131n\u0131n beynin nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131na ili\u015fkin yeni verileri de sa\u011flayaca\u011f\u0131 d\u00fc\u015f\u00fcn\u00fclmekte.<\/p>\n

Kaz\u0131 alanlar\u0131nda \u00e7al\u0131\u015fma yapan arkeologlar, \u00e7amurla kapl\u0131 bir insan kafatas\u0131 buldular, kafatas\u0131n\u0131n i\u00e7erisinde bir par\u00e7as\u0131 korunmu\u015f olan insan beyni ile kar\u015f\u0131la\u015ft\u0131klar\u0131nda ise \u00e7ok \u015fa\u015f\u0131rd\u0131lar. Ard\u0131ndan buluntu \u00fczerinde yap\u0131lan ya\u015f tayini ara\u015ft\u0131rmalar\u0131, bu insan\u0131n M\u00d6 673 ila M\u00d6 482 y\u0131llar\u0131 aras\u0131nda ya\u015fam\u0131n\u0131 yitirdi\u011fini g\u00f6sterdi.<\/p>\n

Biliminsanlar\u0131 yumu\u015fak dokular\u0131n kurutulduklar\u0131nda, dondurulduklar\u0131nda, oksijensiz veya asidik bir ortamda tutulduklar\u0131nda korunabildiklerini ifade ediyor. Buluntuda ise sa\u00e7 dahil olmak \u00fczere v\u00fccudun hi\u00e7bir par\u00e7as\u0131 korunamam\u0131\u015f olmas\u0131na ra\u011fmen beyin yap\u0131s\u0131n\u0131n bir b\u00f6l\u00fcm\u00fcn\u00fcn korunarak g\u00fcn\u00fcm\u00fcze kadar gelebilmi\u015f olmas\u0131 olduk\u00e7a ilgin\u00e7.<\/p>\n

Korunarak g\u00fcn\u00fcm\u00fcze aktar\u0131lan materyali \u00f6zel yapan \u015feyin ne oldu\u011funu ara\u015ft\u0131rmak isteyen biliminsanlar\u0131, buluntudan elde edilen proteinler \u00fczerinde incelemelerde bulundu. \u00c7o\u011fu organ\u0131n aksine beyin, n\u00f6ronlar\u0131n ve kendisinin de bir bile\u015feni oldu\u011fu ba\u011flant\u0131lar\u0131n korunabilmesi i\u00e7in h\u00fccresel d\u00fczeyde de desteklenmek durumundad\u0131r. “IF” ad\u0131 verilen bu proteinler, bahsedilen g\u00f6revi hen\u00fcz canl\u0131 olan beyin dokular\u0131nda yerine getirir. Bu proteinlerin do\u011fru ko\u015fullar alt\u0131nda koruma g\u00f6revi sa\u011flayabilece\u011fi, dolay\u0131s\u0131yla beynin bozulmadan g\u00fcn\u00fcm\u00fcze aktar\u0131lmas\u0131nda role sahip olduklar\u0131 d\u00fc\u015f\u00fcn\u00fclmekte.<\/p>\n

Heslington b\u00f6lgesinden elde edilen buluntuda yap\u0131lan incelemelerde IF ad\u0131 verilen bu protein yap\u0131lar\u0131n\u0131n a\u011f\u0131na rastland\u0131. Ayn\u0131 zamanda bu buluntunun yer ald\u0131\u011f\u0131 b\u00f6lge b\u00f6ylesi bir koruma i\u00e7in uygun asidik \u00f6zellik g\u00f6stermekteydi. 2600 ya\u015f\u0131nda olan bu insan beyninin proteinleri \u00fczerinde yap\u0131lan \u00e7al\u0131\u015fmalara g\u00f6re protein agregatlar (y\u0131\u011f\u0131n) yap\u0131n\u0131n korunmas\u0131na verdikleri destek a\u00e7\u0131s\u0131ndan olduk\u00e7a \u00f6nemli bir yerde duruyor.<\/p>\n

The Royal Society’nin bir yay\u0131n\u0131nda \u00e7\u0131kan makaleye imza atan biliminsanlar\u0131, protein agregatlar \u00fczerindeki \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcrecek. Heslington’dan elde edilen bu beyin yap\u0131s\u0131n\u0131n bize \u00f6\u011fretece\u011fi daha \u00e7ok \u015fey var gibi g\u00f6r\u00fcn\u00fcyor.<\/p>\n

Kaynak:<\/strong>https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rsif.2019.0775
\nhttps:\/\/www.sciencealert.com\/this-study-could-explain-how-human-brain-tissue-remained-intact-for-2-600-years<\/p>\n","protected":false},"excerpt":{"rendered":"

Binlerce y\u0131l \u00f6nce, \u015fimdilerde \u0130ngiltere’de bir k\u00f6y olan Heslington b\u00f6lgesinde bir insan\u0131n cesedi \u00e7evre \u015fartlar\u0131n\u0131n etkisiyle par\u00e7alanmaya ba\u015flad\u0131. Bu par\u00e7alanma s\u0131ras\u0131nda organlar\u0131 \u00e7amurla\u015ft\u0131, sa\u00e7\u0131 toza d\u00f6n\u00fc\u015ft\u00fc. Sonunda, kemikleri ve beyninin k\u00fc\u00e7\u00fck bir par\u00e7as\u0131 kald\u0131. Kemiklerinin g\u00fcn\u00fcm\u00fcze kadar korunarak aktar\u0131lmas\u0131 ola\u011fand\u0131. Ancak beyin par\u00e7as\u0131n\u0131n g\u00fcn\u00fcm\u00fcze kadar darbe almadan ve par\u00e7alanmadan gelmesi s\u0131ra d\u0131\u015f\u0131 bir durumdu. Biliminsanlar\u0131 […]<\/p>\n","protected":false},"author":1390,"featured_media":39645,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[254,5736,1137,1171],"class_list":["post-39643","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-beyin","tag-heslington","tag-kafatasi","tag-protein"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t