Bir vir\u00fcs\u00fcn neden oldu\u011fu raporlanan salg\u0131n hastal\u0131k, \u00c7in\u2019in Hubei eyaletinin ba\u015fkenti olan ve 11 milyon insan\u0131n ya\u015fad\u0131\u011f\u0131 Wuhan \u015fehrinde ortaya \u00e7\u0131kt\u0131.<\/p>\n
Vir\u00fcs d\u00fcnya \u00fczerinde nerelere yay\u0131ld\u0131? Vir\u00fcs\u00fcn kayna\u011f\u0131 ne?<\/strong><\/h4>\nSolunum yolu yetersizli\u011fi \u015fik\u00e2yetleri ilk olarak \u00c7in\u2019in Wuhan b\u00f6lgesinden geldi. Ard\u0131ndan enfeksiyon vakalar\u0131n\u0131n Vietnam, Tayland, Japonya ve G\u00fcney Kore\u2019de de g\u00f6r\u00fcld\u00fc\u011f\u00fc raporland\u0131. Bu vakalar\u0131n haricinde Amerika Birle\u015fik Devletleri, Suudi Arabistan ve \u0130ngiltere\u2019de de bu vir\u00fcsten kaynakl\u0131 hastal\u0131k vakalar\u0131 g\u00f6zlendi.<\/p>\n
Vir\u00fcs nedeniyle \u00f6l\u00fcmler \u015fimdilik sadece Wuhan b\u00f6lgesinde g\u00f6r\u00fcld\u00fc. Ancak Wuhan, daha geni\u015f bir \u00e7evreye yay\u0131lacak olan yeni bir salg\u0131n\u0131n ba\u015flang\u0131\u00e7 noktas\u0131 olabilir. Wuhan b\u00f6lgesi, vah\u015fi hayvan etlerinin sat\u0131ld\u0131\u011f\u0131 ve deniz \u00fcr\u00fcnleri pazarlar\u0131n\u0131n bulundu\u011fu bir b\u00f6lge. Vir\u00fcs\u00fcn temel kayna\u011f\u0131n\u0131n da bu noktalarda sat\u0131lan hayvanlar oldu\u011fu d\u00fc\u015f\u00fcn\u00fcl\u00fcyor. Biliminsanlar\u0131, vir\u00fcs\u00fcn bir hayvandan bir insana ge\u00e7ti\u011fi ve \u015fimdi de insanlar aras\u0131nda yay\u0131ld\u0131\u011f\u0131 konusunda hemfikir. Ara\u015ft\u0131rmac\u0131lar, vir\u00fcs\u00fcn mutasyon ge\u00e7irebilece\u011fini ve daha b\u00fcy\u00fck salg\u0131n\u0131 beraberinde getirebilece\u011fini hat\u0131rlat\u0131yor.<\/p>\n
Salg\u0131n\u0131n ortaya \u00e7\u0131kmas\u0131n\u0131n ard\u0131ndan yap\u0131lan bir \u00e7al\u0131\u015fmada, hastal\u0131\u011fa yakalanan ilk ki\u015filerin, k\u00fcmes hayvanlar\u0131n\u0131n, y\u0131lanlar\u0131n, yarasalar\u0131n ve di\u011fer vah\u015fi hayvanlar\u0131n sat\u0131ld\u0131\u011f\u0131 Huanan deniz \u00fcr\u00fcnleri toptanc\u0131 pazar\u0131na gitmi\u015f ki\u015filer olduklar\u0131 belirtildi. Buna g\u00f6re bu pazara giden ki\u015filer, burada bulunan hayvanlardan bu vir\u00fcs\u00fc kapt\u0131. Vir\u00fcs \u00fczerinde gen dizileme \u00e7al\u0131\u015fmalar\u0131 yapan biliminsanlar\u0131 bu vir\u00fcs\u00fcn kayna\u011f\u0131n\u0131n yarasa ile beslenmi\u015f y\u0131lanlar olabilece\u011fi g\u00f6r\u00fc\u015f\u00fcnde.<\/p>\n
Wuhan’da hastal\u0131\u011fa neden olan vir\u00fcs nedir?<\/strong><\/h4>\nWuhan\u2019da g\u00f6r\u00fclen ve d\u00fcnya geneline yay\u0131lmaya ba\u015flayan bu vir\u00fcs\u00fcn koronavir\u00fcs ailesi i\u00e7erisinde yer alan bir vir\u00fcs t\u00fcr\u00fc oldu\u011fu a\u00e7\u0131kland\u0131. Biliminsanlar\u0131 taraf\u0131ndan yap\u0131lan \u00e7al\u0131\u015fmalar bu vir\u00fcs\u00fcn kayna\u011f\u0131n\u0131 i\u015faret etmekte ancak tedavi metotlar\u0131 konusunda net bir \u00e7al\u0131\u015fma yap\u0131lm\u0131\u015f de\u011fil. Bu vir\u00fcs, daha \u00f6nce tan\u0131mlanmam\u0131\u015f olan yeni bir t\u00fcr koronavir\u00fcst\u00fcr.<\/p>\n
![\"\"](\"https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2020\/01\/koronavir\u00fcs-\u00e7in-300x200.jpg\")
<\/p>\n
Koronavir\u00fcs, hayvanlar aras\u0131nda yayg\u0131n olarak g\u00f6zlenen geni\u015f bir vir\u00fcs ailesidir. Koronavir\u00fcsler (CoV\u2019lar), zarf yap\u0131s\u0131 ta\u015f\u0131yan RNA vir\u00fcsleridir. Y\u00fczeylerinde sivri u\u00e7lar bulunur ve vir\u00fcsler al\u0131\u015f\u0131lmad\u0131k derecede b\u00fcy\u00fck bir RNA genomu ta\u015f\u0131rlar. Benzersiz bir \u00e7o\u011falma kabiliyetleri vard\u0131r. Koronavir\u00fcsler, memelilerde ve ku\u015flarda g\u00f6zlenirler ve insanlarda \u00f6l\u00fcmc\u00fcl solunum yolu enfeksiyonlar\u0131na neden olurlar. Koronavir\u00fcslerin, zoonotik etkiye sahip olduklar\u0131 raporlanm\u0131\u015ft\u0131r. Zoonotik etki, hayvanlardan insanlara ge\u00e7i\u015fi a\u00e7\u0131klar.<\/p>\n
Vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131\u011f\u0131n belirtileri nelerdir? Hastal\u0131k can kayb\u0131na yol a\u00e7t\u0131 m\u0131, vir\u00fcs \u00f6l\u00fcmc\u00fcl m\u00fc?<\/strong><\/h4>\nHastal\u0131k vakalar\u0131 ilk olarak Aral\u0131k ay\u0131n\u0131n son g\u00fcnlerinde ortaya \u00e7\u0131kt\u0131. Vir\u00fcs kaynakl\u0131 bu hastal\u0131\u011f\u0131n tespit edildi\u011fi ilk g\u00fcnden bu yana 17 ki\u015fi ya\u015fam\u0131n\u0131 yitirdi. D\u00fcnya genelinde 600\u2019den fazla enfeksiyon vakas\u0131n\u0131n g\u00f6r\u00fcld\u00fc\u011f\u00fc raporland\u0131. Ya\u015fam\u0131n\u0131 yitiren 17 ki\u015finin tamam\u0131n\u0131n salg\u0131n\u0131n ilk g\u00f6r\u00fcld\u00fc\u011f\u00fc yer olan Wuhan\u2019\u0131n ba\u015fkentli\u011fini yapt\u0131\u011f\u0131 Hubei eyaletinde oldu\u011fu bildirildi. Buna g\u00f6re hastal\u0131\u011f\u0131n \u00f6l\u00fcmc\u00fcl olma oran\u0131 y\u00fczde 11 seviyesinde.<\/p>\n
Wuhan koronavir\u00fcs\u00fc veya \u201c2019-nCoV\u201d olarak adland\u0131r\u0131lan bu vir\u00fcs, \u015fiddetli zat\u00fcrreeye neden oluyor. Hastalar \u00f6ks\u00fcr\u00fck, y\u00fcksek ate\u015f ve nefes alma g\u00fc\u00e7l\u00fc\u011f\u00fc \u015fik\u00e2yetleri ile hastanelere ba\u015fvuruyor. 2003 y\u0131l\u0131nda SARS koronavir\u00fcs\u00fcn\u00fcn neden oldu\u011fu salg\u0131nda oldu\u011fu gibi \u015fiddetli solunum yolu yetersizliklerinin g\u00f6r\u00fcld\u00fc\u011f\u00fc ifade ediliyor.<\/p>\n
Vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131k bula\u015f\u0131c\u0131 m\u0131?<\/strong><\/h4>\nWuhan vir\u00fcs\u00fcn\u00fcn neden oldu\u011fu hastal\u0131\u011f\u0131n insandan insana ge\u00e7ebildi\u011fi ve bula\u015f\u0131c\u0131 etki ta\u015f\u0131d\u0131\u011f\u0131 \u00c7in Ulusal Sa\u011fl\u0131k Komisyonu taraf\u0131ndan a\u00e7\u0131kland\u0131. Ancak bu bula\u015f\u0131c\u0131 etkinin hen\u00fcz 2003 y\u0131l\u0131nda d\u00fcnya genelinde 774 ki\u015finin \u00f6l\u00fcm\u00fcne neden olan SARS vir\u00fcs\u00fcn\u00fcn ta\u015f\u0131d\u0131\u011f\u0131 bula\u015f\u0131c\u0131 etki kadar g\u00fc\u00e7l\u00fc olmad\u0131\u011f\u0131 ifade ediliyor.<\/p>\n
Vir\u00fcs\u00fcn neden oldu\u011fu salg\u0131n \u00f6nceki salg\u0131nlara benziyor mu?<\/strong><\/h4>\n\u015eiddetli akut solunum yolu yetersizli\u011fi olarak da bilinen SARS hastal\u0131\u011f\u0131 da, Orta Do\u011fu solunum yolu sendromu olarak bilinen MERS de hayvanlardan insanlara ge\u00e7en koronavir\u00fcslerden kaynaklanmaktayd\u0131. MERS\u2019in develerden insanlara ge\u00e7ti\u011fi tahmin edilse de hem SARS i\u00e7in hem de MERS i\u00e7in muhtemel kayna\u011f\u0131n yarasalar oldu\u011fu da d\u00fc\u015f\u00fcn\u00fclmektedir. SARS\u2019\u0131n ilk vakalar\u0131 yine \u00c7in\u2019de g\u00f6r\u00fclm\u00fc\u015ft\u00fc. D\u00fcnya genelinde 8500\u2019den fazla ki\u015finin SARS vir\u00fcs\u00fcnden etkilendi\u011fi ve 750\u2019den fazla insan\u0131n SARS vir\u00fcs\u00fc (SARS-CoV) nedeniyle ya\u015fam\u0131n\u0131 yitirdi\u011fi d\u00fc\u015f\u00fcn\u00fclmektedir. MERS vir\u00fcs\u00fcn\u00fcn (MERS-CoV) neden oldu\u011fu hastal\u0131k ise d\u00fcnya genelinde 37 \u00fclkeye yay\u0131lm\u0131\u015f ve hasta olan yakla\u015f\u0131k 2500 ki\u015finin y\u00fczde 35\u2019i ya\u015fam\u0131n\u0131 yitirmi\u015ftir.<\/p>\n
Wuhan\u2019da etkili olan vir\u00fcs de SARS ve MERS vir\u00fcslerinin bulundu\u011fu vir\u00fcs ailesinde yer al\u0131yor. \u201c2019-nCoV\u201d olarak isimlendirilen bu vir\u00fcs\u00fcn de \u00f6nceki salg\u0131nlara benzer y\u0131k\u0131c\u0131 etkilere sahip oldu\u011fu ifade edilmekte.<\/p>\n
Hastal\u0131k ne kadar yay\u0131ld\u0131, salg\u0131n d\u00fcnyay\u0131 tehdit ediyor mu?<\/strong><\/h4>\n![\"\"](\"https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2020\/01\/\u00e7in-koronavir\u00fcs-salg\u0131n\u0131-300x169.jpg\")
<\/p>\n
23 Ocak itibariyle \u00c7in\u2019de 517 enfeksiyon vakas\u0131n\u0131n oldu\u011fu ve 17 ki\u015finin de ya\u015fam\u0131n\u0131 yitirdi\u011fi raporland\u0131. Ge\u00e7ti\u011fimiz haftadan beri etkinli\u011fini art\u0131ran bu vir\u00fcs\u00fcn Pekin, \u015eangay, Chongqing ve Tianjin gibi 13 b\u00f6lgeye yay\u0131ld\u0131\u011f\u0131 a\u00e7\u0131kland\u0131. Hen\u00fcz hastal\u0131\u011f\u0131n ba\u015flang\u0131c\u0131nda olan ve semptomlar\u0131 hen\u00fcz hafif seviyede g\u00f6zlenen ki\u015filerin salg\u0131ndan etkilenip etkilenmedikleri do\u011frudan anla\u015f\u0131lamad\u0131\u011f\u0131 i\u00e7in vir\u00fcs\u00fc ta\u015f\u0131y\u0131p ta\u015f\u0131mad\u0131klar\u0131 da bilinemiyor. Bu nedenle vir\u00fcs\u00fcn d\u00fcnya \u00fczerine ne kadar yay\u0131ld\u0131\u011f\u0131 hen\u00fcz tespit edilebilmi\u015f de\u011fil. Biliminsanlar\u0131, vir\u00fcs\u00fc ta\u015f\u0131yan ki\u015filerin ger\u00e7ek say\u0131s\u0131n\u0131n \u00e7ok daha y\u00fcksek olabilece\u011fini a\u00e7\u0131klad\u0131. Konuya ili\u015fkin olarak yap\u0131lan bir ba\u015fka \u00e7al\u0131\u015fma d\u00fcnya genelinde 4.000 vakan\u0131n olabilece\u011fini ve vaka say\u0131s\u0131n\u0131n 9700\u2019e kadar ula\u015fabilece\u011fini ortaya koydu.<\/p>\n
\u00c7in Yeni Y\u0131l\u0131 i\u00e7in 24 Ocak g\u00fcn\u00fc tatilin ba\u015flayaca\u011f\u0131 \u00c7in\u2019de salg\u0131n\u0131n yay\u0131labilece\u011finden endi\u015fe ediliyor. Grip ve benzeri vir\u00fctik hastal\u0131klarda ve mikroorganizmalar\u0131n neden oldu\u011fu di\u011fer hastal\u0131klarda oldu\u011fu gibi ba\u011f\u0131\u015f\u0131kl\u0131k sistemi g\u00fc\u00e7l\u00fc olmayan ki\u015filer risk grubunu olu\u015fturuyor. \u00d6zellikle de \u00fclke d\u0131\u015f\u0131na seyahatlerin vir\u00fcs\u00fcn yay\u0131lma h\u0131z\u0131n\u0131 artt\u0131rmas\u0131ndan endi\u015fe ediliyor.<\/p>\n
Bu vir\u00fcsle sava\u015fmakta en etkin yolun g\u00fc\u00e7l\u00fc bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemi oldu\u011funu vurgulayan biliminsanlar\u0131, d\u00fcnya genelindeki vakalar\u0131n \u00e7o\u011funlu\u011funun ya\u015fl\u0131lar oldu\u011funu ifade etti. Az say\u0131da \u00e7ocu\u011fun bu vir\u00fcsten etkilendi\u011fi a\u00e7\u0131kland\u0131.<\/p>\n
Wuhan vir\u00fcs\u00fcne kar\u015f\u0131 geli\u015ftirilen tedavi metotlar\u0131 var m\u0131?<\/strong><\/h4>\nHastal\u0131k vir\u00fcs k\u00f6kenli oldu\u011fu i\u00e7in kullan\u0131lan antibiyotiklerin tedavi edici i\u015flevi yoktur. Bu durumda antiviral \u00f6zellik g\u00f6steren ila\u00e7lar kullan\u0131labilir. Ancak bu ila\u00e7lar genellikle vir\u00fcs\u00fcn etkileri ile m\u00fccadele etmek i\u00e7in tasarlanm\u0131\u015ft\u0131r. Bu nedenle sadece semptomlar\u0131n y\u0131k\u0131c\u0131 etkisini azalt\u0131r, vir\u00fcs ile do\u011frudan bir m\u00fccadele y\u00fcr\u00fctmez. Hastane ko\u015fullar\u0131nda ise solunum deste\u011fi, s\u0131v\u0131 deste\u011fi gibi uygulamalarla ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fc\u00e7l\u00fc kalmas\u0131 sa\u011flanabilir. Ancak bu y\u00f6ntem sadece ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 g\u00fc\u00e7lendirmek i\u00e7in i\u015fe yarayacakt\u0131r. Vir\u00fcs ve di\u011fer mikroorganizmalar kaynakl\u0131 hastal\u0131klarda ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fcc\u00fc olduk\u00e7a \u00f6nemlidir. Bu nedenle bu y\u00f6ntem hastalar\u0131 do\u011frudan tedavi etmese de geli\u015ftirilen tedavi metotlar\u0131n\u0131n etkili olmas\u0131n\u0131 sa\u011flayabilir.<\/p>\n
Bu noktada bu vir\u00fcs nedeniyle ya\u015fam\u0131n\u0131 yitiren ki\u015filerin ba\u011f\u0131\u015f\u0131kl\u0131k sistemi g\u00fc\u00e7l\u00fc olmayan ve hali haz\u0131rda grip ve benzeri hastal\u0131klara yakalanm\u0131\u015f olan ki\u015filer oldu\u011fu belirtiliyor.<\/p>\n
Vir\u00fcs\u00fcn genetik dizisini bilmek tedavi i\u00e7in yeni metotlar sunar m\u0131?<\/strong><\/h4>\n![\"\"](\"https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2020\/01\/koronavir\u00fcs-300x169.jpg\")
Wuhan vir\u00fcs\u00fcn\u00fcn genetik yap\u0131s\u0131 hakk\u0131nda bilgi sahibi olunmas\u0131, bu vir\u00fcs\u00fcn k\u00f6kenleri ve yay\u0131l\u0131m\u0131 hakk\u0131nda ipu\u00e7lar\u0131 sunar. \u00c7in ve Tayland\u2019da bulunan laboratuvarlarda bu vir\u00fcs taraf\u0131ndan enfekte edilmi\u015f insanlardan al\u0131nan \u00f6rnekler incelendi. Haz\u0131rlanan 19 su\u015fun genom dizilimi yap\u0131ld\u0131. Biliminsanlar\u0131, bu vir\u00fcs t\u00fcr\u00fcndeki \u00e7e\u015fitlili\u011fi de incelediler. Genetik \u00e7e\u015fitlili\u011fin beklenenden az oldu\u011funu belirten ara\u015ft\u0131rmac\u0131lar, bunun nedenleri hakk\u0131nda da a\u00e7\u0131klamalarda bulundu. Biliminsanlar\u0131na g\u00f6re, bu vir\u00fcs Kas\u0131m ve Aral\u0131k aylar\u0131nda ortaya \u00e7\u0131kt\u0131, h\u0131zla yay\u0131ld\u0131 ancak bu s\u00fcre i\u00e7erisinde genetik \u00e7e\u015fitlili\u011fi y\u00fcksek oranda sa\u011flayacak kadar mutasyon ge\u00e7irmedi. Ara\u015ft\u0131rmac\u0131lar, vir\u00fcslerin ge\u00e7irdi\u011fi mutasyonlarla birlikte kazand\u0131\u011f\u0131 mevcut \u00e7e\u015fitlili\u011fin insanlarda m\u0131 yoksa vir\u00fcs\u00fcn ana kayna\u011f\u0131 olan hayvanlar da m\u0131 ger\u00e7ekle\u015fti\u011fini hen\u00fcz tespit edemediler.<\/p>\n
Biliminsalar\u0131, \u00e7al\u0131\u015fmalar\u0131na devam ederek bu vir\u00fcs\u00fcn hayvanlardan insanlara ge\u00e7i\u015findeki genetik de\u011fi\u015fimleri inceleyeceklerini ifade ediyor. Ayr\u0131ca bu vir\u00fcs\u00fcn insandan insana ge\u00e7erek daha kolay bir yay\u0131l\u0131m g\u00f6sterip g\u00f6stermedi\u011fi de analiz edilecek.<\/p>\n
Vir\u00fcs ve yay\u0131lma s\u00fcreciyle ilgili \u015fimdiye kadar neler yap\u0131ld\u0131?<\/strong><\/h4>\n\u00c7in\u2019de ortaya \u00e7\u0131kan bu vir\u00fcs\u00fcn daha da yay\u0131lmas\u0131n\u0131n \u00f6n\u00fcne ge\u00e7mek i\u00e7in Wuhan i\u00e7indeki ve d\u0131\u015f\u0131ndaki t\u00fcm seyahatler durduruldu. 23 Ocak itibariyle bu \u015fehirden kalkan u\u00e7aklar\u0131n ve bir ba\u015fka ula\u015f\u0131m arac\u0131 olan trenlerin kullan\u0131m\u0131 yasakland\u0131, \u015fehirde karantina uygulamas\u0131 ba\u015flat\u0131ld\u0131. Otob\u00fcs ile metro seferleri de durduruldu. Bu uygulaman\u0131n \u00fclkeler aras\u0131 yay\u0131l\u0131mda etkili olabilece\u011fi ancak vir\u00fcs\u00fcn \u00fclke i\u00e7erisindeki yay\u0131l\u0131m\u0131n\u0131 \u00f6nlemeyece\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n
![\"\"](\"https:\/\/bilimvegelecek.com.tr\/wp-content\/uploads\/2020\/01\/wuhan-300x169.jpg\")
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Yetkililer Wuhan\u2019da ya\u015fayan ki\u015filerin \u015fehri terk etmemesi gerekti\u011fini vurguluyor. Wuhan\u2019da otoyol kontrol noktalar\u0131na, tren istasyonlar\u0131na ve havaalanlar\u0131na y\u00fcksek ate\u015fi fark eden taray\u0131c\u0131lar yerle\u015ftirildi. Wuhan\u2019daki uluslararas\u0131 havaliman\u0131 104 noktaya hizmet sa\u011fl\u0131yor. Havaliman\u0131nda bulunan u\u00e7aklar\u0131n kullan\u0131m\u0131 bu nedenle durduruldu. Wuhan\u2019dan u\u00e7u\u015flar\u0131n yap\u0131ld\u0131\u011f\u0131 ABD\u2019deki \u00fc\u00e7 havaliman\u0131nda ve Do\u011fu Asya\u2019daki \u00fclkelerin havalimanlar\u0131nda da kontroller ba\u015flat\u0131ld\u0131.<\/p>\n
D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc ise, salg\u0131n\u0131n k\u00fcresel bir halk sa\u011fl\u0131\u011f\u0131 problemi olarak benimsenip acil durum ilan edilip edilmemesi \u00fczerine toplant\u0131lar d\u00fczenliyor. 22 Ocak\u2019ta yap\u0131lan toplant\u0131n\u0131n ard\u0131ndan acil durum ilan\u0131n\u0131n ertelendi\u011fi ifade edilmi\u015fti.<\/p>\n
(Bu i\u00e7erik, Wuhan koronavir\u00fcs\u00fcne ili\u015fkin 23 Ocak g\u00fcn\u00fcne kadar elde edilen verilerden ve konuya ili\u015fkin \u00e7al\u0131\u015fmalardan yararlan\u0131larak haz\u0131rlanm\u0131\u015ft\u0131r. Wuhan koronavir\u00fcs\u00fcne ili\u015fkin ara\u015ft\u0131rmalara her ge\u00e7en g\u00fcn yenisi eklenmektedir. Vir\u00fcs d\u00fcnya genelinde yay\u0131lmaktad\u0131r ancak biliminsanlar\u0131 hem vir\u00fcs\u00fcn k\u00f6keni hem de uygulanabilecek tedavi metotlar\u0131 \u00fczerine \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcr\u00fcyorlar.)<\/p>\n
Kaynak:<\/strong> https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4369385\/
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00166-6
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/where-has-coronavirus-spread
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/23\/what-is-the-wuhan-coronavirus-and-how-worried-should-we-be
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/coronavirus-heathrow-to-create-separate-arrival-area
\nhttps:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jmv.25682?fbclid=IwAR3bLSJdOTW-ZbgEDyWaSrPiBl2bVQeipBnR5ExF40ZOq-_5UXOZ5ZXdxR0
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00154-w<\/p>\n","protected":false},"excerpt":{"rendered":"Biliminsanlar\u0131 ve d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131nda \u00e7al\u0131\u015fma y\u00fcr\u00fcten sa\u011fl\u0131k personeli, ge\u00e7en ay ortaya \u00e7\u0131kan bir vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131k nedeniyle olduk\u00e7a endi\u015feli. \u015eiddetli solunum yolu yetersizli\u011fine neden olan bu vir\u00fcs\u00fcn zamanla yay\u0131l\u0131yor olmas\u0131 endi\u015felerin b\u00fcy\u00fcmesine neden oluyor. Peki bu salg\u0131n d\u00fcnya geneline yay\u0131lacak m\u0131? Bu hastal\u0131\u011f\u0131n kayna\u011f\u0131 ne? Tedavi metotlar\u0131 var m\u0131? 10 soru ve […]<\/p>\n","protected":false},"author":1390,"featured_media":39835,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[609,5765,5763,5764,492,5762],"class_list":["post-39831","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-cin","tag-karantina","tag-koronavirus","tag-salgin","tag-virus","tag-wuhan"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t
Wuhan\u2019da g\u00f6r\u00fclen ve d\u00fcnya geneline yay\u0131lmaya ba\u015flayan bu vir\u00fcs\u00fcn koronavir\u00fcs ailesi i\u00e7erisinde yer alan bir vir\u00fcs t\u00fcr\u00fc oldu\u011fu a\u00e7\u0131kland\u0131. Biliminsanlar\u0131 taraf\u0131ndan yap\u0131lan \u00e7al\u0131\u015fmalar bu vir\u00fcs\u00fcn kayna\u011f\u0131n\u0131 i\u015faret etmekte ancak tedavi metotlar\u0131 konusunda net bir \u00e7al\u0131\u015fma yap\u0131lm\u0131\u015f de\u011fil. Bu vir\u00fcs, daha \u00f6nce tan\u0131mlanmam\u0131\u015f olan yeni bir t\u00fcr koronavir\u00fcst\u00fcr.<\/p>\n
<\/p>\n
Koronavir\u00fcs, hayvanlar aras\u0131nda yayg\u0131n olarak g\u00f6zlenen geni\u015f bir vir\u00fcs ailesidir. Koronavir\u00fcsler (CoV\u2019lar), zarf yap\u0131s\u0131 ta\u015f\u0131yan RNA vir\u00fcsleridir. Y\u00fczeylerinde sivri u\u00e7lar bulunur ve vir\u00fcsler al\u0131\u015f\u0131lmad\u0131k derecede b\u00fcy\u00fck bir RNA genomu ta\u015f\u0131rlar. Benzersiz bir \u00e7o\u011falma kabiliyetleri vard\u0131r. Koronavir\u00fcsler, memelilerde ve ku\u015flarda g\u00f6zlenirler ve insanlarda \u00f6l\u00fcmc\u00fcl solunum yolu enfeksiyonlar\u0131na neden olurlar. Koronavir\u00fcslerin, zoonotik etkiye sahip olduklar\u0131 raporlanm\u0131\u015ft\u0131r. Zoonotik etki, hayvanlardan insanlara ge\u00e7i\u015fi a\u00e7\u0131klar.<\/p>\n
Vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131\u011f\u0131n belirtileri nelerdir? Hastal\u0131k can kayb\u0131na yol a\u00e7t\u0131 m\u0131, vir\u00fcs \u00f6l\u00fcmc\u00fcl m\u00fc?<\/strong><\/h4>\nHastal\u0131k vakalar\u0131 ilk olarak Aral\u0131k ay\u0131n\u0131n son g\u00fcnlerinde ortaya \u00e7\u0131kt\u0131. Vir\u00fcs kaynakl\u0131 bu hastal\u0131\u011f\u0131n tespit edildi\u011fi ilk g\u00fcnden bu yana 17 ki\u015fi ya\u015fam\u0131n\u0131 yitirdi. D\u00fcnya genelinde 600\u2019den fazla enfeksiyon vakas\u0131n\u0131n g\u00f6r\u00fcld\u00fc\u011f\u00fc raporland\u0131. Ya\u015fam\u0131n\u0131 yitiren 17 ki\u015finin tamam\u0131n\u0131n salg\u0131n\u0131n ilk g\u00f6r\u00fcld\u00fc\u011f\u00fc yer olan Wuhan\u2019\u0131n ba\u015fkentli\u011fini yapt\u0131\u011f\u0131 Hubei eyaletinde oldu\u011fu bildirildi. Buna g\u00f6re hastal\u0131\u011f\u0131n \u00f6l\u00fcmc\u00fcl olma oran\u0131 y\u00fczde 11 seviyesinde.<\/p>\n
Wuhan koronavir\u00fcs\u00fc veya \u201c2019-nCoV\u201d olarak adland\u0131r\u0131lan bu vir\u00fcs, \u015fiddetli zat\u00fcrreeye neden oluyor. Hastalar \u00f6ks\u00fcr\u00fck, y\u00fcksek ate\u015f ve nefes alma g\u00fc\u00e7l\u00fc\u011f\u00fc \u015fik\u00e2yetleri ile hastanelere ba\u015fvuruyor. 2003 y\u0131l\u0131nda SARS koronavir\u00fcs\u00fcn\u00fcn neden oldu\u011fu salg\u0131nda oldu\u011fu gibi \u015fiddetli solunum yolu yetersizliklerinin g\u00f6r\u00fcld\u00fc\u011f\u00fc ifade ediliyor.<\/p>\n
Vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131k bula\u015f\u0131c\u0131 m\u0131?<\/strong><\/h4>\nWuhan vir\u00fcs\u00fcn\u00fcn neden oldu\u011fu hastal\u0131\u011f\u0131n insandan insana ge\u00e7ebildi\u011fi ve bula\u015f\u0131c\u0131 etki ta\u015f\u0131d\u0131\u011f\u0131 \u00c7in Ulusal Sa\u011fl\u0131k Komisyonu taraf\u0131ndan a\u00e7\u0131kland\u0131. Ancak bu bula\u015f\u0131c\u0131 etkinin hen\u00fcz 2003 y\u0131l\u0131nda d\u00fcnya genelinde 774 ki\u015finin \u00f6l\u00fcm\u00fcne neden olan SARS vir\u00fcs\u00fcn\u00fcn ta\u015f\u0131d\u0131\u011f\u0131 bula\u015f\u0131c\u0131 etki kadar g\u00fc\u00e7l\u00fc olmad\u0131\u011f\u0131 ifade ediliyor.<\/p>\n
Vir\u00fcs\u00fcn neden oldu\u011fu salg\u0131n \u00f6nceki salg\u0131nlara benziyor mu?<\/strong><\/h4>\n\u015eiddetli akut solunum yolu yetersizli\u011fi olarak da bilinen SARS hastal\u0131\u011f\u0131 da, Orta Do\u011fu solunum yolu sendromu olarak bilinen MERS de hayvanlardan insanlara ge\u00e7en koronavir\u00fcslerden kaynaklanmaktayd\u0131. MERS\u2019in develerden insanlara ge\u00e7ti\u011fi tahmin edilse de hem SARS i\u00e7in hem de MERS i\u00e7in muhtemel kayna\u011f\u0131n yarasalar oldu\u011fu da d\u00fc\u015f\u00fcn\u00fclmektedir. SARS\u2019\u0131n ilk vakalar\u0131 yine \u00c7in\u2019de g\u00f6r\u00fclm\u00fc\u015ft\u00fc. D\u00fcnya genelinde 8500\u2019den fazla ki\u015finin SARS vir\u00fcs\u00fcnden etkilendi\u011fi ve 750\u2019den fazla insan\u0131n SARS vir\u00fcs\u00fc (SARS-CoV) nedeniyle ya\u015fam\u0131n\u0131 yitirdi\u011fi d\u00fc\u015f\u00fcn\u00fclmektedir. MERS vir\u00fcs\u00fcn\u00fcn (MERS-CoV) neden oldu\u011fu hastal\u0131k ise d\u00fcnya genelinde 37 \u00fclkeye yay\u0131lm\u0131\u015f ve hasta olan yakla\u015f\u0131k 2500 ki\u015finin y\u00fczde 35\u2019i ya\u015fam\u0131n\u0131 yitirmi\u015ftir.<\/p>\n
Wuhan\u2019da etkili olan vir\u00fcs de SARS ve MERS vir\u00fcslerinin bulundu\u011fu vir\u00fcs ailesinde yer al\u0131yor. \u201c2019-nCoV\u201d olarak isimlendirilen bu vir\u00fcs\u00fcn de \u00f6nceki salg\u0131nlara benzer y\u0131k\u0131c\u0131 etkilere sahip oldu\u011fu ifade edilmekte.<\/p>\n
Hastal\u0131k ne kadar yay\u0131ld\u0131, salg\u0131n d\u00fcnyay\u0131 tehdit ediyor mu?<\/strong><\/h4>\n<\/p>\n
23 Ocak itibariyle \u00c7in\u2019de 517 enfeksiyon vakas\u0131n\u0131n oldu\u011fu ve 17 ki\u015finin de ya\u015fam\u0131n\u0131 yitirdi\u011fi raporland\u0131. Ge\u00e7ti\u011fimiz haftadan beri etkinli\u011fini art\u0131ran bu vir\u00fcs\u00fcn Pekin, \u015eangay, Chongqing ve Tianjin gibi 13 b\u00f6lgeye yay\u0131ld\u0131\u011f\u0131 a\u00e7\u0131kland\u0131. Hen\u00fcz hastal\u0131\u011f\u0131n ba\u015flang\u0131c\u0131nda olan ve semptomlar\u0131 hen\u00fcz hafif seviyede g\u00f6zlenen ki\u015filerin salg\u0131ndan etkilenip etkilenmedikleri do\u011frudan anla\u015f\u0131lamad\u0131\u011f\u0131 i\u00e7in vir\u00fcs\u00fc ta\u015f\u0131y\u0131p ta\u015f\u0131mad\u0131klar\u0131 da bilinemiyor. Bu nedenle vir\u00fcs\u00fcn d\u00fcnya \u00fczerine ne kadar yay\u0131ld\u0131\u011f\u0131 hen\u00fcz tespit edilebilmi\u015f de\u011fil. Biliminsanlar\u0131, vir\u00fcs\u00fc ta\u015f\u0131yan ki\u015filerin ger\u00e7ek say\u0131s\u0131n\u0131n \u00e7ok daha y\u00fcksek olabilece\u011fini a\u00e7\u0131klad\u0131. Konuya ili\u015fkin olarak yap\u0131lan bir ba\u015fka \u00e7al\u0131\u015fma d\u00fcnya genelinde 4.000 vakan\u0131n olabilece\u011fini ve vaka say\u0131s\u0131n\u0131n 9700\u2019e kadar ula\u015fabilece\u011fini ortaya koydu.<\/p>\n
\u00c7in Yeni Y\u0131l\u0131 i\u00e7in 24 Ocak g\u00fcn\u00fc tatilin ba\u015flayaca\u011f\u0131 \u00c7in\u2019de salg\u0131n\u0131n yay\u0131labilece\u011finden endi\u015fe ediliyor. Grip ve benzeri vir\u00fctik hastal\u0131klarda ve mikroorganizmalar\u0131n neden oldu\u011fu di\u011fer hastal\u0131klarda oldu\u011fu gibi ba\u011f\u0131\u015f\u0131kl\u0131k sistemi g\u00fc\u00e7l\u00fc olmayan ki\u015filer risk grubunu olu\u015fturuyor. \u00d6zellikle de \u00fclke d\u0131\u015f\u0131na seyahatlerin vir\u00fcs\u00fcn yay\u0131lma h\u0131z\u0131n\u0131 artt\u0131rmas\u0131ndan endi\u015fe ediliyor.<\/p>\n
Bu vir\u00fcsle sava\u015fmakta en etkin yolun g\u00fc\u00e7l\u00fc bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemi oldu\u011funu vurgulayan biliminsanlar\u0131, d\u00fcnya genelindeki vakalar\u0131n \u00e7o\u011funlu\u011funun ya\u015fl\u0131lar oldu\u011funu ifade etti. Az say\u0131da \u00e7ocu\u011fun bu vir\u00fcsten etkilendi\u011fi a\u00e7\u0131kland\u0131.<\/p>\n
Wuhan vir\u00fcs\u00fcne kar\u015f\u0131 geli\u015ftirilen tedavi metotlar\u0131 var m\u0131?<\/strong><\/h4>\nHastal\u0131k vir\u00fcs k\u00f6kenli oldu\u011fu i\u00e7in kullan\u0131lan antibiyotiklerin tedavi edici i\u015flevi yoktur. Bu durumda antiviral \u00f6zellik g\u00f6steren ila\u00e7lar kullan\u0131labilir. Ancak bu ila\u00e7lar genellikle vir\u00fcs\u00fcn etkileri ile m\u00fccadele etmek i\u00e7in tasarlanm\u0131\u015ft\u0131r. Bu nedenle sadece semptomlar\u0131n y\u0131k\u0131c\u0131 etkisini azalt\u0131r, vir\u00fcs ile do\u011frudan bir m\u00fccadele y\u00fcr\u00fctmez. Hastane ko\u015fullar\u0131nda ise solunum deste\u011fi, s\u0131v\u0131 deste\u011fi gibi uygulamalarla ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fc\u00e7l\u00fc kalmas\u0131 sa\u011flanabilir. Ancak bu y\u00f6ntem sadece ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 g\u00fc\u00e7lendirmek i\u00e7in i\u015fe yarayacakt\u0131r. Vir\u00fcs ve di\u011fer mikroorganizmalar kaynakl\u0131 hastal\u0131klarda ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fcc\u00fc olduk\u00e7a \u00f6nemlidir. Bu nedenle bu y\u00f6ntem hastalar\u0131 do\u011frudan tedavi etmese de geli\u015ftirilen tedavi metotlar\u0131n\u0131n etkili olmas\u0131n\u0131 sa\u011flayabilir.<\/p>\n
Bu noktada bu vir\u00fcs nedeniyle ya\u015fam\u0131n\u0131 yitiren ki\u015filerin ba\u011f\u0131\u015f\u0131kl\u0131k sistemi g\u00fc\u00e7l\u00fc olmayan ve hali haz\u0131rda grip ve benzeri hastal\u0131klara yakalanm\u0131\u015f olan ki\u015filer oldu\u011fu belirtiliyor.<\/p>\n
Vir\u00fcs\u00fcn genetik dizisini bilmek tedavi i\u00e7in yeni metotlar sunar m\u0131?<\/strong><\/h4>\nWuhan vir\u00fcs\u00fcn\u00fcn genetik yap\u0131s\u0131 hakk\u0131nda bilgi sahibi olunmas\u0131, bu vir\u00fcs\u00fcn k\u00f6kenleri ve yay\u0131l\u0131m\u0131 hakk\u0131nda ipu\u00e7lar\u0131 sunar. \u00c7in ve Tayland\u2019da bulunan laboratuvarlarda bu vir\u00fcs taraf\u0131ndan enfekte edilmi\u015f insanlardan al\u0131nan \u00f6rnekler incelendi. Haz\u0131rlanan 19 su\u015fun genom dizilimi yap\u0131ld\u0131. Biliminsanlar\u0131, bu vir\u00fcs t\u00fcr\u00fcndeki \u00e7e\u015fitlili\u011fi de incelediler. Genetik \u00e7e\u015fitlili\u011fin beklenenden az oldu\u011funu belirten ara\u015ft\u0131rmac\u0131lar, bunun nedenleri hakk\u0131nda da a\u00e7\u0131klamalarda bulundu. Biliminsanlar\u0131na g\u00f6re, bu vir\u00fcs Kas\u0131m ve Aral\u0131k aylar\u0131nda ortaya \u00e7\u0131kt\u0131, h\u0131zla yay\u0131ld\u0131 ancak bu s\u00fcre i\u00e7erisinde genetik \u00e7e\u015fitlili\u011fi y\u00fcksek oranda sa\u011flayacak kadar mutasyon ge\u00e7irmedi. Ara\u015ft\u0131rmac\u0131lar, vir\u00fcslerin ge\u00e7irdi\u011fi mutasyonlarla birlikte kazand\u0131\u011f\u0131 mevcut \u00e7e\u015fitlili\u011fin insanlarda m\u0131 yoksa vir\u00fcs\u00fcn ana kayna\u011f\u0131 olan hayvanlar da m\u0131 ger\u00e7ekle\u015fti\u011fini hen\u00fcz tespit edemediler.<\/p>\n
Biliminsalar\u0131, \u00e7al\u0131\u015fmalar\u0131na devam ederek bu vir\u00fcs\u00fcn hayvanlardan insanlara ge\u00e7i\u015findeki genetik de\u011fi\u015fimleri inceleyeceklerini ifade ediyor. Ayr\u0131ca bu vir\u00fcs\u00fcn insandan insana ge\u00e7erek daha kolay bir yay\u0131l\u0131m g\u00f6sterip g\u00f6stermedi\u011fi de analiz edilecek.<\/p>\n
Vir\u00fcs ve yay\u0131lma s\u00fcreciyle ilgili \u015fimdiye kadar neler yap\u0131ld\u0131?<\/strong><\/h4>\n\u00c7in\u2019de ortaya \u00e7\u0131kan bu vir\u00fcs\u00fcn daha da yay\u0131lmas\u0131n\u0131n \u00f6n\u00fcne ge\u00e7mek i\u00e7in Wuhan i\u00e7indeki ve d\u0131\u015f\u0131ndaki t\u00fcm seyahatler durduruldu. 23 Ocak itibariyle bu \u015fehirden kalkan u\u00e7aklar\u0131n ve bir ba\u015fka ula\u015f\u0131m arac\u0131 olan trenlerin kullan\u0131m\u0131 yasakland\u0131, \u015fehirde karantina uygulamas\u0131 ba\u015flat\u0131ld\u0131. Otob\u00fcs ile metro seferleri de durduruldu. Bu uygulaman\u0131n \u00fclkeler aras\u0131 yay\u0131l\u0131mda etkili olabilece\u011fi ancak vir\u00fcs\u00fcn \u00fclke i\u00e7erisindeki yay\u0131l\u0131m\u0131n\u0131 \u00f6nlemeyece\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n
<\/p>\n
Yetkililer Wuhan\u2019da ya\u015fayan ki\u015filerin \u015fehri terk etmemesi gerekti\u011fini vurguluyor. Wuhan\u2019da otoyol kontrol noktalar\u0131na, tren istasyonlar\u0131na ve havaalanlar\u0131na y\u00fcksek ate\u015fi fark eden taray\u0131c\u0131lar yerle\u015ftirildi. Wuhan\u2019daki uluslararas\u0131 havaliman\u0131 104 noktaya hizmet sa\u011fl\u0131yor. Havaliman\u0131nda bulunan u\u00e7aklar\u0131n kullan\u0131m\u0131 bu nedenle durduruldu. Wuhan\u2019dan u\u00e7u\u015flar\u0131n yap\u0131ld\u0131\u011f\u0131 ABD\u2019deki \u00fc\u00e7 havaliman\u0131nda ve Do\u011fu Asya\u2019daki \u00fclkelerin havalimanlar\u0131nda da kontroller ba\u015flat\u0131ld\u0131.<\/p>\n
D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc ise, salg\u0131n\u0131n k\u00fcresel bir halk sa\u011fl\u0131\u011f\u0131 problemi olarak benimsenip acil durum ilan edilip edilmemesi \u00fczerine toplant\u0131lar d\u00fczenliyor. 22 Ocak\u2019ta yap\u0131lan toplant\u0131n\u0131n ard\u0131ndan acil durum ilan\u0131n\u0131n ertelendi\u011fi ifade edilmi\u015fti.<\/p>\n
(Bu i\u00e7erik, Wuhan koronavir\u00fcs\u00fcne ili\u015fkin 23 Ocak g\u00fcn\u00fcne kadar elde edilen verilerden ve konuya ili\u015fkin \u00e7al\u0131\u015fmalardan yararlan\u0131larak haz\u0131rlanm\u0131\u015ft\u0131r. Wuhan koronavir\u00fcs\u00fcne ili\u015fkin ara\u015ft\u0131rmalara her ge\u00e7en g\u00fcn yenisi eklenmektedir. Vir\u00fcs d\u00fcnya genelinde yay\u0131lmaktad\u0131r ancak biliminsanlar\u0131 hem vir\u00fcs\u00fcn k\u00f6keni hem de uygulanabilecek tedavi metotlar\u0131 \u00fczerine \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcr\u00fcyorlar.)<\/p>\n
Kaynak:<\/strong> https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4369385\/
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00166-6
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/where-has-coronavirus-spread
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/23\/what-is-the-wuhan-coronavirus-and-how-worried-should-we-be
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/coronavirus-heathrow-to-create-separate-arrival-area
\nhttps:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jmv.25682?fbclid=IwAR3bLSJdOTW-ZbgEDyWaSrPiBl2bVQeipBnR5ExF40ZOq-_5UXOZ5ZXdxR0
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00154-w<\/p>\n","protected":false},"excerpt":{"rendered":"Biliminsanlar\u0131 ve d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131nda \u00e7al\u0131\u015fma y\u00fcr\u00fcten sa\u011fl\u0131k personeli, ge\u00e7en ay ortaya \u00e7\u0131kan bir vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131k nedeniyle olduk\u00e7a endi\u015feli. \u015eiddetli solunum yolu yetersizli\u011fine neden olan bu vir\u00fcs\u00fcn zamanla yay\u0131l\u0131yor olmas\u0131 endi\u015felerin b\u00fcy\u00fcmesine neden oluyor. Peki bu salg\u0131n d\u00fcnya geneline yay\u0131lacak m\u0131? Bu hastal\u0131\u011f\u0131n kayna\u011f\u0131 ne? Tedavi metotlar\u0131 var m\u0131? 10 soru ve […]<\/p>\n","protected":false},"author":1390,"featured_media":39835,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[609,5765,5763,5764,492,5762],"class_list":["post-39831","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-cin","tag-karantina","tag-koronavirus","tag-salgin","tag-virus","tag-wuhan"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t
Wuhan vir\u00fcs\u00fcn\u00fcn neden oldu\u011fu hastal\u0131\u011f\u0131n insandan insana ge\u00e7ebildi\u011fi ve bula\u015f\u0131c\u0131 etki ta\u015f\u0131d\u0131\u011f\u0131 \u00c7in Ulusal Sa\u011fl\u0131k Komisyonu taraf\u0131ndan a\u00e7\u0131kland\u0131. Ancak bu bula\u015f\u0131c\u0131 etkinin hen\u00fcz 2003 y\u0131l\u0131nda d\u00fcnya genelinde 774 ki\u015finin \u00f6l\u00fcm\u00fcne neden olan SARS vir\u00fcs\u00fcn\u00fcn ta\u015f\u0131d\u0131\u011f\u0131 bula\u015f\u0131c\u0131 etki kadar g\u00fc\u00e7l\u00fc olmad\u0131\u011f\u0131 ifade ediliyor.<\/p>\n
Vir\u00fcs\u00fcn neden oldu\u011fu salg\u0131n \u00f6nceki salg\u0131nlara benziyor mu?<\/strong><\/h4>\n\u015eiddetli akut solunum yolu yetersizli\u011fi olarak da bilinen SARS hastal\u0131\u011f\u0131 da, Orta Do\u011fu solunum yolu sendromu olarak bilinen MERS de hayvanlardan insanlara ge\u00e7en koronavir\u00fcslerden kaynaklanmaktayd\u0131. MERS\u2019in develerden insanlara ge\u00e7ti\u011fi tahmin edilse de hem SARS i\u00e7in hem de MERS i\u00e7in muhtemel kayna\u011f\u0131n yarasalar oldu\u011fu da d\u00fc\u015f\u00fcn\u00fclmektedir. SARS\u2019\u0131n ilk vakalar\u0131 yine \u00c7in\u2019de g\u00f6r\u00fclm\u00fc\u015ft\u00fc. D\u00fcnya genelinde 8500\u2019den fazla ki\u015finin SARS vir\u00fcs\u00fcnden etkilendi\u011fi ve 750\u2019den fazla insan\u0131n SARS vir\u00fcs\u00fc (SARS-CoV) nedeniyle ya\u015fam\u0131n\u0131 yitirdi\u011fi d\u00fc\u015f\u00fcn\u00fclmektedir. MERS vir\u00fcs\u00fcn\u00fcn (MERS-CoV) neden oldu\u011fu hastal\u0131k ise d\u00fcnya genelinde 37 \u00fclkeye yay\u0131lm\u0131\u015f ve hasta olan yakla\u015f\u0131k 2500 ki\u015finin y\u00fczde 35\u2019i ya\u015fam\u0131n\u0131 yitirmi\u015ftir.<\/p>\n
Wuhan\u2019da etkili olan vir\u00fcs de SARS ve MERS vir\u00fcslerinin bulundu\u011fu vir\u00fcs ailesinde yer al\u0131yor. \u201c2019-nCoV\u201d olarak isimlendirilen bu vir\u00fcs\u00fcn de \u00f6nceki salg\u0131nlara benzer y\u0131k\u0131c\u0131 etkilere sahip oldu\u011fu ifade edilmekte.<\/p>\n
Hastal\u0131k ne kadar yay\u0131ld\u0131, salg\u0131n d\u00fcnyay\u0131 tehdit ediyor mu?<\/strong><\/h4>\n<\/p>\n
23 Ocak itibariyle \u00c7in\u2019de 517 enfeksiyon vakas\u0131n\u0131n oldu\u011fu ve 17 ki\u015finin de ya\u015fam\u0131n\u0131 yitirdi\u011fi raporland\u0131. Ge\u00e7ti\u011fimiz haftadan beri etkinli\u011fini art\u0131ran bu vir\u00fcs\u00fcn Pekin, \u015eangay, Chongqing ve Tianjin gibi 13 b\u00f6lgeye yay\u0131ld\u0131\u011f\u0131 a\u00e7\u0131kland\u0131. Hen\u00fcz hastal\u0131\u011f\u0131n ba\u015flang\u0131c\u0131nda olan ve semptomlar\u0131 hen\u00fcz hafif seviyede g\u00f6zlenen ki\u015filerin salg\u0131ndan etkilenip etkilenmedikleri do\u011frudan anla\u015f\u0131lamad\u0131\u011f\u0131 i\u00e7in vir\u00fcs\u00fc ta\u015f\u0131y\u0131p ta\u015f\u0131mad\u0131klar\u0131 da bilinemiyor. Bu nedenle vir\u00fcs\u00fcn d\u00fcnya \u00fczerine ne kadar yay\u0131ld\u0131\u011f\u0131 hen\u00fcz tespit edilebilmi\u015f de\u011fil. Biliminsanlar\u0131, vir\u00fcs\u00fc ta\u015f\u0131yan ki\u015filerin ger\u00e7ek say\u0131s\u0131n\u0131n \u00e7ok daha y\u00fcksek olabilece\u011fini a\u00e7\u0131klad\u0131. Konuya ili\u015fkin olarak yap\u0131lan bir ba\u015fka \u00e7al\u0131\u015fma d\u00fcnya genelinde 4.000 vakan\u0131n olabilece\u011fini ve vaka say\u0131s\u0131n\u0131n 9700\u2019e kadar ula\u015fabilece\u011fini ortaya koydu.<\/p>\n
\u00c7in Yeni Y\u0131l\u0131 i\u00e7in 24 Ocak g\u00fcn\u00fc tatilin ba\u015flayaca\u011f\u0131 \u00c7in\u2019de salg\u0131n\u0131n yay\u0131labilece\u011finden endi\u015fe ediliyor. Grip ve benzeri vir\u00fctik hastal\u0131klarda ve mikroorganizmalar\u0131n neden oldu\u011fu di\u011fer hastal\u0131klarda oldu\u011fu gibi ba\u011f\u0131\u015f\u0131kl\u0131k sistemi g\u00fc\u00e7l\u00fc olmayan ki\u015filer risk grubunu olu\u015fturuyor. \u00d6zellikle de \u00fclke d\u0131\u015f\u0131na seyahatlerin vir\u00fcs\u00fcn yay\u0131lma h\u0131z\u0131n\u0131 artt\u0131rmas\u0131ndan endi\u015fe ediliyor.<\/p>\n
Bu vir\u00fcsle sava\u015fmakta en etkin yolun g\u00fc\u00e7l\u00fc bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemi oldu\u011funu vurgulayan biliminsanlar\u0131, d\u00fcnya genelindeki vakalar\u0131n \u00e7o\u011funlu\u011funun ya\u015fl\u0131lar oldu\u011funu ifade etti. Az say\u0131da \u00e7ocu\u011fun bu vir\u00fcsten etkilendi\u011fi a\u00e7\u0131kland\u0131.<\/p>\n
Wuhan vir\u00fcs\u00fcne kar\u015f\u0131 geli\u015ftirilen tedavi metotlar\u0131 var m\u0131?<\/strong><\/h4>\nHastal\u0131k vir\u00fcs k\u00f6kenli oldu\u011fu i\u00e7in kullan\u0131lan antibiyotiklerin tedavi edici i\u015flevi yoktur. Bu durumda antiviral \u00f6zellik g\u00f6steren ila\u00e7lar kullan\u0131labilir. Ancak bu ila\u00e7lar genellikle vir\u00fcs\u00fcn etkileri ile m\u00fccadele etmek i\u00e7in tasarlanm\u0131\u015ft\u0131r. Bu nedenle sadece semptomlar\u0131n y\u0131k\u0131c\u0131 etkisini azalt\u0131r, vir\u00fcs ile do\u011frudan bir m\u00fccadele y\u00fcr\u00fctmez. Hastane ko\u015fullar\u0131nda ise solunum deste\u011fi, s\u0131v\u0131 deste\u011fi gibi uygulamalarla ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fc\u00e7l\u00fc kalmas\u0131 sa\u011flanabilir. Ancak bu y\u00f6ntem sadece ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 g\u00fc\u00e7lendirmek i\u00e7in i\u015fe yarayacakt\u0131r. Vir\u00fcs ve di\u011fer mikroorganizmalar kaynakl\u0131 hastal\u0131klarda ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fcc\u00fc olduk\u00e7a \u00f6nemlidir. Bu nedenle bu y\u00f6ntem hastalar\u0131 do\u011frudan tedavi etmese de geli\u015ftirilen tedavi metotlar\u0131n\u0131n etkili olmas\u0131n\u0131 sa\u011flayabilir.<\/p>\n
Bu noktada bu vir\u00fcs nedeniyle ya\u015fam\u0131n\u0131 yitiren ki\u015filerin ba\u011f\u0131\u015f\u0131kl\u0131k sistemi g\u00fc\u00e7l\u00fc olmayan ve hali haz\u0131rda grip ve benzeri hastal\u0131klara yakalanm\u0131\u015f olan ki\u015filer oldu\u011fu belirtiliyor.<\/p>\n
Vir\u00fcs\u00fcn genetik dizisini bilmek tedavi i\u00e7in yeni metotlar sunar m\u0131?<\/strong><\/h4>\nWuhan vir\u00fcs\u00fcn\u00fcn genetik yap\u0131s\u0131 hakk\u0131nda bilgi sahibi olunmas\u0131, bu vir\u00fcs\u00fcn k\u00f6kenleri ve yay\u0131l\u0131m\u0131 hakk\u0131nda ipu\u00e7lar\u0131 sunar. \u00c7in ve Tayland\u2019da bulunan laboratuvarlarda bu vir\u00fcs taraf\u0131ndan enfekte edilmi\u015f insanlardan al\u0131nan \u00f6rnekler incelendi. Haz\u0131rlanan 19 su\u015fun genom dizilimi yap\u0131ld\u0131. Biliminsanlar\u0131, bu vir\u00fcs t\u00fcr\u00fcndeki \u00e7e\u015fitlili\u011fi de incelediler. Genetik \u00e7e\u015fitlili\u011fin beklenenden az oldu\u011funu belirten ara\u015ft\u0131rmac\u0131lar, bunun nedenleri hakk\u0131nda da a\u00e7\u0131klamalarda bulundu. Biliminsanlar\u0131na g\u00f6re, bu vir\u00fcs Kas\u0131m ve Aral\u0131k aylar\u0131nda ortaya \u00e7\u0131kt\u0131, h\u0131zla yay\u0131ld\u0131 ancak bu s\u00fcre i\u00e7erisinde genetik \u00e7e\u015fitlili\u011fi y\u00fcksek oranda sa\u011flayacak kadar mutasyon ge\u00e7irmedi. Ara\u015ft\u0131rmac\u0131lar, vir\u00fcslerin ge\u00e7irdi\u011fi mutasyonlarla birlikte kazand\u0131\u011f\u0131 mevcut \u00e7e\u015fitlili\u011fin insanlarda m\u0131 yoksa vir\u00fcs\u00fcn ana kayna\u011f\u0131 olan hayvanlar da m\u0131 ger\u00e7ekle\u015fti\u011fini hen\u00fcz tespit edemediler.<\/p>\n
Biliminsalar\u0131, \u00e7al\u0131\u015fmalar\u0131na devam ederek bu vir\u00fcs\u00fcn hayvanlardan insanlara ge\u00e7i\u015findeki genetik de\u011fi\u015fimleri inceleyeceklerini ifade ediyor. Ayr\u0131ca bu vir\u00fcs\u00fcn insandan insana ge\u00e7erek daha kolay bir yay\u0131l\u0131m g\u00f6sterip g\u00f6stermedi\u011fi de analiz edilecek.<\/p>\n
Vir\u00fcs ve yay\u0131lma s\u00fcreciyle ilgili \u015fimdiye kadar neler yap\u0131ld\u0131?<\/strong><\/h4>\n\u00c7in\u2019de ortaya \u00e7\u0131kan bu vir\u00fcs\u00fcn daha da yay\u0131lmas\u0131n\u0131n \u00f6n\u00fcne ge\u00e7mek i\u00e7in Wuhan i\u00e7indeki ve d\u0131\u015f\u0131ndaki t\u00fcm seyahatler durduruldu. 23 Ocak itibariyle bu \u015fehirden kalkan u\u00e7aklar\u0131n ve bir ba\u015fka ula\u015f\u0131m arac\u0131 olan trenlerin kullan\u0131m\u0131 yasakland\u0131, \u015fehirde karantina uygulamas\u0131 ba\u015flat\u0131ld\u0131. Otob\u00fcs ile metro seferleri de durduruldu. Bu uygulaman\u0131n \u00fclkeler aras\u0131 yay\u0131l\u0131mda etkili olabilece\u011fi ancak vir\u00fcs\u00fcn \u00fclke i\u00e7erisindeki yay\u0131l\u0131m\u0131n\u0131 \u00f6nlemeyece\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n
<\/p>\n
Yetkililer Wuhan\u2019da ya\u015fayan ki\u015filerin \u015fehri terk etmemesi gerekti\u011fini vurguluyor. Wuhan\u2019da otoyol kontrol noktalar\u0131na, tren istasyonlar\u0131na ve havaalanlar\u0131na y\u00fcksek ate\u015fi fark eden taray\u0131c\u0131lar yerle\u015ftirildi. Wuhan\u2019daki uluslararas\u0131 havaliman\u0131 104 noktaya hizmet sa\u011fl\u0131yor. Havaliman\u0131nda bulunan u\u00e7aklar\u0131n kullan\u0131m\u0131 bu nedenle durduruldu. Wuhan\u2019dan u\u00e7u\u015flar\u0131n yap\u0131ld\u0131\u011f\u0131 ABD\u2019deki \u00fc\u00e7 havaliman\u0131nda ve Do\u011fu Asya\u2019daki \u00fclkelerin havalimanlar\u0131nda da kontroller ba\u015flat\u0131ld\u0131.<\/p>\n
D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc ise, salg\u0131n\u0131n k\u00fcresel bir halk sa\u011fl\u0131\u011f\u0131 problemi olarak benimsenip acil durum ilan edilip edilmemesi \u00fczerine toplant\u0131lar d\u00fczenliyor. 22 Ocak\u2019ta yap\u0131lan toplant\u0131n\u0131n ard\u0131ndan acil durum ilan\u0131n\u0131n ertelendi\u011fi ifade edilmi\u015fti.<\/p>\n
(Bu i\u00e7erik, Wuhan koronavir\u00fcs\u00fcne ili\u015fkin 23 Ocak g\u00fcn\u00fcne kadar elde edilen verilerden ve konuya ili\u015fkin \u00e7al\u0131\u015fmalardan yararlan\u0131larak haz\u0131rlanm\u0131\u015ft\u0131r. Wuhan koronavir\u00fcs\u00fcne ili\u015fkin ara\u015ft\u0131rmalara her ge\u00e7en g\u00fcn yenisi eklenmektedir. Vir\u00fcs d\u00fcnya genelinde yay\u0131lmaktad\u0131r ancak biliminsanlar\u0131 hem vir\u00fcs\u00fcn k\u00f6keni hem de uygulanabilecek tedavi metotlar\u0131 \u00fczerine \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcr\u00fcyorlar.)<\/p>\n
Kaynak:<\/strong> https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4369385\/
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00166-6
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/where-has-coronavirus-spread
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/23\/what-is-the-wuhan-coronavirus-and-how-worried-should-we-be
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/coronavirus-heathrow-to-create-separate-arrival-area
\nhttps:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jmv.25682?fbclid=IwAR3bLSJdOTW-ZbgEDyWaSrPiBl2bVQeipBnR5ExF40ZOq-_5UXOZ5ZXdxR0
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00154-w<\/p>\n","protected":false},"excerpt":{"rendered":"Biliminsanlar\u0131 ve d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131nda \u00e7al\u0131\u015fma y\u00fcr\u00fcten sa\u011fl\u0131k personeli, ge\u00e7en ay ortaya \u00e7\u0131kan bir vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131k nedeniyle olduk\u00e7a endi\u015feli. \u015eiddetli solunum yolu yetersizli\u011fine neden olan bu vir\u00fcs\u00fcn zamanla yay\u0131l\u0131yor olmas\u0131 endi\u015felerin b\u00fcy\u00fcmesine neden oluyor. Peki bu salg\u0131n d\u00fcnya geneline yay\u0131lacak m\u0131? Bu hastal\u0131\u011f\u0131n kayna\u011f\u0131 ne? Tedavi metotlar\u0131 var m\u0131? 10 soru ve […]<\/p>\n","protected":false},"author":1390,"featured_media":39835,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[609,5765,5763,5764,492,5762],"class_list":["post-39831","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-cin","tag-karantina","tag-koronavirus","tag-salgin","tag-virus","tag-wuhan"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t
<\/p>\n
23 Ocak itibariyle \u00c7in\u2019de 517 enfeksiyon vakas\u0131n\u0131n oldu\u011fu ve 17 ki\u015finin de ya\u015fam\u0131n\u0131 yitirdi\u011fi raporland\u0131. Ge\u00e7ti\u011fimiz haftadan beri etkinli\u011fini art\u0131ran bu vir\u00fcs\u00fcn Pekin, \u015eangay, Chongqing ve Tianjin gibi 13 b\u00f6lgeye yay\u0131ld\u0131\u011f\u0131 a\u00e7\u0131kland\u0131. Hen\u00fcz hastal\u0131\u011f\u0131n ba\u015flang\u0131c\u0131nda olan ve semptomlar\u0131 hen\u00fcz hafif seviyede g\u00f6zlenen ki\u015filerin salg\u0131ndan etkilenip etkilenmedikleri do\u011frudan anla\u015f\u0131lamad\u0131\u011f\u0131 i\u00e7in vir\u00fcs\u00fc ta\u015f\u0131y\u0131p ta\u015f\u0131mad\u0131klar\u0131 da bilinemiyor. Bu nedenle vir\u00fcs\u00fcn d\u00fcnya \u00fczerine ne kadar yay\u0131ld\u0131\u011f\u0131 hen\u00fcz tespit edilebilmi\u015f de\u011fil. Biliminsanlar\u0131, vir\u00fcs\u00fc ta\u015f\u0131yan ki\u015filerin ger\u00e7ek say\u0131s\u0131n\u0131n \u00e7ok daha y\u00fcksek olabilece\u011fini a\u00e7\u0131klad\u0131. Konuya ili\u015fkin olarak yap\u0131lan bir ba\u015fka \u00e7al\u0131\u015fma d\u00fcnya genelinde 4.000 vakan\u0131n olabilece\u011fini ve vaka say\u0131s\u0131n\u0131n 9700\u2019e kadar ula\u015fabilece\u011fini ortaya koydu.<\/p>\n
\u00c7in Yeni Y\u0131l\u0131 i\u00e7in 24 Ocak g\u00fcn\u00fc tatilin ba\u015flayaca\u011f\u0131 \u00c7in\u2019de salg\u0131n\u0131n yay\u0131labilece\u011finden endi\u015fe ediliyor. Grip ve benzeri vir\u00fctik hastal\u0131klarda ve mikroorganizmalar\u0131n neden oldu\u011fu di\u011fer hastal\u0131klarda oldu\u011fu gibi ba\u011f\u0131\u015f\u0131kl\u0131k sistemi g\u00fc\u00e7l\u00fc olmayan ki\u015filer risk grubunu olu\u015fturuyor. \u00d6zellikle de \u00fclke d\u0131\u015f\u0131na seyahatlerin vir\u00fcs\u00fcn yay\u0131lma h\u0131z\u0131n\u0131 artt\u0131rmas\u0131ndan endi\u015fe ediliyor.<\/p>\n
Bu vir\u00fcsle sava\u015fmakta en etkin yolun g\u00fc\u00e7l\u00fc bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemi oldu\u011funu vurgulayan biliminsanlar\u0131, d\u00fcnya genelindeki vakalar\u0131n \u00e7o\u011funlu\u011funun ya\u015fl\u0131lar oldu\u011funu ifade etti. Az say\u0131da \u00e7ocu\u011fun bu vir\u00fcsten etkilendi\u011fi a\u00e7\u0131kland\u0131.<\/p>\n
Wuhan vir\u00fcs\u00fcne kar\u015f\u0131 geli\u015ftirilen tedavi metotlar\u0131 var m\u0131?<\/strong><\/h4>\nHastal\u0131k vir\u00fcs k\u00f6kenli oldu\u011fu i\u00e7in kullan\u0131lan antibiyotiklerin tedavi edici i\u015flevi yoktur. Bu durumda antiviral \u00f6zellik g\u00f6steren ila\u00e7lar kullan\u0131labilir. Ancak bu ila\u00e7lar genellikle vir\u00fcs\u00fcn etkileri ile m\u00fccadele etmek i\u00e7in tasarlanm\u0131\u015ft\u0131r. Bu nedenle sadece semptomlar\u0131n y\u0131k\u0131c\u0131 etkisini azalt\u0131r, vir\u00fcs ile do\u011frudan bir m\u00fccadele y\u00fcr\u00fctmez. Hastane ko\u015fullar\u0131nda ise solunum deste\u011fi, s\u0131v\u0131 deste\u011fi gibi uygulamalarla ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fc\u00e7l\u00fc kalmas\u0131 sa\u011flanabilir. Ancak bu y\u00f6ntem sadece ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 g\u00fc\u00e7lendirmek i\u00e7in i\u015fe yarayacakt\u0131r. Vir\u00fcs ve di\u011fer mikroorganizmalar kaynakl\u0131 hastal\u0131klarda ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fcc\u00fc olduk\u00e7a \u00f6nemlidir. Bu nedenle bu y\u00f6ntem hastalar\u0131 do\u011frudan tedavi etmese de geli\u015ftirilen tedavi metotlar\u0131n\u0131n etkili olmas\u0131n\u0131 sa\u011flayabilir.<\/p>\n
Bu noktada bu vir\u00fcs nedeniyle ya\u015fam\u0131n\u0131 yitiren ki\u015filerin ba\u011f\u0131\u015f\u0131kl\u0131k sistemi g\u00fc\u00e7l\u00fc olmayan ve hali haz\u0131rda grip ve benzeri hastal\u0131klara yakalanm\u0131\u015f olan ki\u015filer oldu\u011fu belirtiliyor.<\/p>\n
Vir\u00fcs\u00fcn genetik dizisini bilmek tedavi i\u00e7in yeni metotlar sunar m\u0131?<\/strong><\/h4>\nWuhan vir\u00fcs\u00fcn\u00fcn genetik yap\u0131s\u0131 hakk\u0131nda bilgi sahibi olunmas\u0131, bu vir\u00fcs\u00fcn k\u00f6kenleri ve yay\u0131l\u0131m\u0131 hakk\u0131nda ipu\u00e7lar\u0131 sunar. \u00c7in ve Tayland\u2019da bulunan laboratuvarlarda bu vir\u00fcs taraf\u0131ndan enfekte edilmi\u015f insanlardan al\u0131nan \u00f6rnekler incelendi. Haz\u0131rlanan 19 su\u015fun genom dizilimi yap\u0131ld\u0131. Biliminsanlar\u0131, bu vir\u00fcs t\u00fcr\u00fcndeki \u00e7e\u015fitlili\u011fi de incelediler. Genetik \u00e7e\u015fitlili\u011fin beklenenden az oldu\u011funu belirten ara\u015ft\u0131rmac\u0131lar, bunun nedenleri hakk\u0131nda da a\u00e7\u0131klamalarda bulundu. Biliminsanlar\u0131na g\u00f6re, bu vir\u00fcs Kas\u0131m ve Aral\u0131k aylar\u0131nda ortaya \u00e7\u0131kt\u0131, h\u0131zla yay\u0131ld\u0131 ancak bu s\u00fcre i\u00e7erisinde genetik \u00e7e\u015fitlili\u011fi y\u00fcksek oranda sa\u011flayacak kadar mutasyon ge\u00e7irmedi. Ara\u015ft\u0131rmac\u0131lar, vir\u00fcslerin ge\u00e7irdi\u011fi mutasyonlarla birlikte kazand\u0131\u011f\u0131 mevcut \u00e7e\u015fitlili\u011fin insanlarda m\u0131 yoksa vir\u00fcs\u00fcn ana kayna\u011f\u0131 olan hayvanlar da m\u0131 ger\u00e7ekle\u015fti\u011fini hen\u00fcz tespit edemediler.<\/p>\n
Biliminsalar\u0131, \u00e7al\u0131\u015fmalar\u0131na devam ederek bu vir\u00fcs\u00fcn hayvanlardan insanlara ge\u00e7i\u015findeki genetik de\u011fi\u015fimleri inceleyeceklerini ifade ediyor. Ayr\u0131ca bu vir\u00fcs\u00fcn insandan insana ge\u00e7erek daha kolay bir yay\u0131l\u0131m g\u00f6sterip g\u00f6stermedi\u011fi de analiz edilecek.<\/p>\n
Vir\u00fcs ve yay\u0131lma s\u00fcreciyle ilgili \u015fimdiye kadar neler yap\u0131ld\u0131?<\/strong><\/h4>\n\u00c7in\u2019de ortaya \u00e7\u0131kan bu vir\u00fcs\u00fcn daha da yay\u0131lmas\u0131n\u0131n \u00f6n\u00fcne ge\u00e7mek i\u00e7in Wuhan i\u00e7indeki ve d\u0131\u015f\u0131ndaki t\u00fcm seyahatler durduruldu. 23 Ocak itibariyle bu \u015fehirden kalkan u\u00e7aklar\u0131n ve bir ba\u015fka ula\u015f\u0131m arac\u0131 olan trenlerin kullan\u0131m\u0131 yasakland\u0131, \u015fehirde karantina uygulamas\u0131 ba\u015flat\u0131ld\u0131. Otob\u00fcs ile metro seferleri de durduruldu. Bu uygulaman\u0131n \u00fclkeler aras\u0131 yay\u0131l\u0131mda etkili olabilece\u011fi ancak vir\u00fcs\u00fcn \u00fclke i\u00e7erisindeki yay\u0131l\u0131m\u0131n\u0131 \u00f6nlemeyece\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n
<\/p>\n
Yetkililer Wuhan\u2019da ya\u015fayan ki\u015filerin \u015fehri terk etmemesi gerekti\u011fini vurguluyor. Wuhan\u2019da otoyol kontrol noktalar\u0131na, tren istasyonlar\u0131na ve havaalanlar\u0131na y\u00fcksek ate\u015fi fark eden taray\u0131c\u0131lar yerle\u015ftirildi. Wuhan\u2019daki uluslararas\u0131 havaliman\u0131 104 noktaya hizmet sa\u011fl\u0131yor. Havaliman\u0131nda bulunan u\u00e7aklar\u0131n kullan\u0131m\u0131 bu nedenle durduruldu. Wuhan\u2019dan u\u00e7u\u015flar\u0131n yap\u0131ld\u0131\u011f\u0131 ABD\u2019deki \u00fc\u00e7 havaliman\u0131nda ve Do\u011fu Asya\u2019daki \u00fclkelerin havalimanlar\u0131nda da kontroller ba\u015flat\u0131ld\u0131.<\/p>\n
D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc ise, salg\u0131n\u0131n k\u00fcresel bir halk sa\u011fl\u0131\u011f\u0131 problemi olarak benimsenip acil durum ilan edilip edilmemesi \u00fczerine toplant\u0131lar d\u00fczenliyor. 22 Ocak\u2019ta yap\u0131lan toplant\u0131n\u0131n ard\u0131ndan acil durum ilan\u0131n\u0131n ertelendi\u011fi ifade edilmi\u015fti.<\/p>\n
(Bu i\u00e7erik, Wuhan koronavir\u00fcs\u00fcne ili\u015fkin 23 Ocak g\u00fcn\u00fcne kadar elde edilen verilerden ve konuya ili\u015fkin \u00e7al\u0131\u015fmalardan yararlan\u0131larak haz\u0131rlanm\u0131\u015ft\u0131r. Wuhan koronavir\u00fcs\u00fcne ili\u015fkin ara\u015ft\u0131rmalara her ge\u00e7en g\u00fcn yenisi eklenmektedir. Vir\u00fcs d\u00fcnya genelinde yay\u0131lmaktad\u0131r ancak biliminsanlar\u0131 hem vir\u00fcs\u00fcn k\u00f6keni hem de uygulanabilecek tedavi metotlar\u0131 \u00fczerine \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcr\u00fcyorlar.)<\/p>\n
Kaynak:<\/strong> https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4369385\/
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00166-6
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/where-has-coronavirus-spread
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/23\/what-is-the-wuhan-coronavirus-and-how-worried-should-we-be
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/coronavirus-heathrow-to-create-separate-arrival-area
\nhttps:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jmv.25682?fbclid=IwAR3bLSJdOTW-ZbgEDyWaSrPiBl2bVQeipBnR5ExF40ZOq-_5UXOZ5ZXdxR0
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00154-w<\/p>\n","protected":false},"excerpt":{"rendered":"Biliminsanlar\u0131 ve d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131nda \u00e7al\u0131\u015fma y\u00fcr\u00fcten sa\u011fl\u0131k personeli, ge\u00e7en ay ortaya \u00e7\u0131kan bir vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131k nedeniyle olduk\u00e7a endi\u015feli. \u015eiddetli solunum yolu yetersizli\u011fine neden olan bu vir\u00fcs\u00fcn zamanla yay\u0131l\u0131yor olmas\u0131 endi\u015felerin b\u00fcy\u00fcmesine neden oluyor. Peki bu salg\u0131n d\u00fcnya geneline yay\u0131lacak m\u0131? Bu hastal\u0131\u011f\u0131n kayna\u011f\u0131 ne? Tedavi metotlar\u0131 var m\u0131? 10 soru ve […]<\/p>\n","protected":false},"author":1390,"featured_media":39835,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[609,5765,5763,5764,492,5762],"class_list":["post-39831","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-cin","tag-karantina","tag-koronavirus","tag-salgin","tag-virus","tag-wuhan"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t
Wuhan vir\u00fcs\u00fcn\u00fcn genetik yap\u0131s\u0131 hakk\u0131nda bilgi sahibi olunmas\u0131, bu vir\u00fcs\u00fcn k\u00f6kenleri ve yay\u0131l\u0131m\u0131 hakk\u0131nda ipu\u00e7lar\u0131 sunar. \u00c7in ve Tayland\u2019da bulunan laboratuvarlarda bu vir\u00fcs taraf\u0131ndan enfekte edilmi\u015f insanlardan al\u0131nan \u00f6rnekler incelendi. Haz\u0131rlanan 19 su\u015fun genom dizilimi yap\u0131ld\u0131. Biliminsanlar\u0131, bu vir\u00fcs t\u00fcr\u00fcndeki \u00e7e\u015fitlili\u011fi de incelediler. Genetik \u00e7e\u015fitlili\u011fin beklenenden az oldu\u011funu belirten ara\u015ft\u0131rmac\u0131lar, bunun nedenleri hakk\u0131nda da a\u00e7\u0131klamalarda bulundu. Biliminsanlar\u0131na g\u00f6re, bu vir\u00fcs Kas\u0131m ve Aral\u0131k aylar\u0131nda ortaya \u00e7\u0131kt\u0131, h\u0131zla yay\u0131ld\u0131 ancak bu s\u00fcre i\u00e7erisinde genetik \u00e7e\u015fitlili\u011fi y\u00fcksek oranda sa\u011flayacak kadar mutasyon ge\u00e7irmedi. Ara\u015ft\u0131rmac\u0131lar, vir\u00fcslerin ge\u00e7irdi\u011fi mutasyonlarla birlikte kazand\u0131\u011f\u0131 mevcut \u00e7e\u015fitlili\u011fin insanlarda m\u0131 yoksa vir\u00fcs\u00fcn ana kayna\u011f\u0131 olan hayvanlar da m\u0131 ger\u00e7ekle\u015fti\u011fini hen\u00fcz tespit edemediler.<\/p>\n
Biliminsalar\u0131, \u00e7al\u0131\u015fmalar\u0131na devam ederek bu vir\u00fcs\u00fcn hayvanlardan insanlara ge\u00e7i\u015findeki genetik de\u011fi\u015fimleri inceleyeceklerini ifade ediyor. Ayr\u0131ca bu vir\u00fcs\u00fcn insandan insana ge\u00e7erek daha kolay bir yay\u0131l\u0131m g\u00f6sterip g\u00f6stermedi\u011fi de analiz edilecek.<\/p>\n
Vir\u00fcs ve yay\u0131lma s\u00fcreciyle ilgili \u015fimdiye kadar neler yap\u0131ld\u0131?<\/strong><\/h4>\n\u00c7in\u2019de ortaya \u00e7\u0131kan bu vir\u00fcs\u00fcn daha da yay\u0131lmas\u0131n\u0131n \u00f6n\u00fcne ge\u00e7mek i\u00e7in Wuhan i\u00e7indeki ve d\u0131\u015f\u0131ndaki t\u00fcm seyahatler durduruldu. 23 Ocak itibariyle bu \u015fehirden kalkan u\u00e7aklar\u0131n ve bir ba\u015fka ula\u015f\u0131m arac\u0131 olan trenlerin kullan\u0131m\u0131 yasakland\u0131, \u015fehirde karantina uygulamas\u0131 ba\u015flat\u0131ld\u0131. Otob\u00fcs ile metro seferleri de durduruldu. Bu uygulaman\u0131n \u00fclkeler aras\u0131 yay\u0131l\u0131mda etkili olabilece\u011fi ancak vir\u00fcs\u00fcn \u00fclke i\u00e7erisindeki yay\u0131l\u0131m\u0131n\u0131 \u00f6nlemeyece\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n
<\/p>\n
Yetkililer Wuhan\u2019da ya\u015fayan ki\u015filerin \u015fehri terk etmemesi gerekti\u011fini vurguluyor. Wuhan\u2019da otoyol kontrol noktalar\u0131na, tren istasyonlar\u0131na ve havaalanlar\u0131na y\u00fcksek ate\u015fi fark eden taray\u0131c\u0131lar yerle\u015ftirildi. Wuhan\u2019daki uluslararas\u0131 havaliman\u0131 104 noktaya hizmet sa\u011fl\u0131yor. Havaliman\u0131nda bulunan u\u00e7aklar\u0131n kullan\u0131m\u0131 bu nedenle durduruldu. Wuhan\u2019dan u\u00e7u\u015flar\u0131n yap\u0131ld\u0131\u011f\u0131 ABD\u2019deki \u00fc\u00e7 havaliman\u0131nda ve Do\u011fu Asya\u2019daki \u00fclkelerin havalimanlar\u0131nda da kontroller ba\u015flat\u0131ld\u0131.<\/p>\n
D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc ise, salg\u0131n\u0131n k\u00fcresel bir halk sa\u011fl\u0131\u011f\u0131 problemi olarak benimsenip acil durum ilan edilip edilmemesi \u00fczerine toplant\u0131lar d\u00fczenliyor. 22 Ocak\u2019ta yap\u0131lan toplant\u0131n\u0131n ard\u0131ndan acil durum ilan\u0131n\u0131n ertelendi\u011fi ifade edilmi\u015fti.<\/p>\n
(Bu i\u00e7erik, Wuhan koronavir\u00fcs\u00fcne ili\u015fkin 23 Ocak g\u00fcn\u00fcne kadar elde edilen verilerden ve konuya ili\u015fkin \u00e7al\u0131\u015fmalardan yararlan\u0131larak haz\u0131rlanm\u0131\u015ft\u0131r. Wuhan koronavir\u00fcs\u00fcne ili\u015fkin ara\u015ft\u0131rmalara her ge\u00e7en g\u00fcn yenisi eklenmektedir. Vir\u00fcs d\u00fcnya genelinde yay\u0131lmaktad\u0131r ancak biliminsanlar\u0131 hem vir\u00fcs\u00fcn k\u00f6keni hem de uygulanabilecek tedavi metotlar\u0131 \u00fczerine \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcr\u00fcyorlar.)<\/p>\n
Kaynak:<\/strong> https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4369385\/
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00166-6
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/where-has-coronavirus-spread
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/23\/what-is-the-wuhan-coronavirus-and-how-worried-should-we-be
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/coronavirus-heathrow-to-create-separate-arrival-area
\nhttps:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jmv.25682?fbclid=IwAR3bLSJdOTW-ZbgEDyWaSrPiBl2bVQeipBnR5ExF40ZOq-_5UXOZ5ZXdxR0
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00154-w<\/p>\n","protected":false},"excerpt":{"rendered":"Biliminsanlar\u0131 ve d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131nda \u00e7al\u0131\u015fma y\u00fcr\u00fcten sa\u011fl\u0131k personeli, ge\u00e7en ay ortaya \u00e7\u0131kan bir vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131k nedeniyle olduk\u00e7a endi\u015feli. \u015eiddetli solunum yolu yetersizli\u011fine neden olan bu vir\u00fcs\u00fcn zamanla yay\u0131l\u0131yor olmas\u0131 endi\u015felerin b\u00fcy\u00fcmesine neden oluyor. Peki bu salg\u0131n d\u00fcnya geneline yay\u0131lacak m\u0131? Bu hastal\u0131\u011f\u0131n kayna\u011f\u0131 ne? Tedavi metotlar\u0131 var m\u0131? 10 soru ve […]<\/p>\n","protected":false},"author":1390,"featured_media":39835,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[609,5765,5763,5764,492,5762],"class_list":["post-39831","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-cin","tag-karantina","tag-koronavirus","tag-salgin","tag-virus","tag-wuhan"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t
<\/p>\n\nhttps:\/\/www.nature.com\/articles\/d41586-020-00166-6
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/where-has-coronavirus-spread
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/23\/what-is-the-wuhan-coronavirus-and-how-worried-should-we-be
\nhttps:\/\/www.theguardian.com\/science\/2020\/jan\/22\/coronavirus-heathrow-to-create-separate-arrival-area
\nhttps:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jmv.25682?fbclid=IwAR3bLSJdOTW-ZbgEDyWaSrPiBl2bVQeipBnR5ExF40ZOq-_5UXOZ5ZXdxR0
\nhttps:\/\/www.nature.com\/articles\/d41586-020-00154-w<\/p>\n","protected":false},"excerpt":{"rendered":"
Biliminsanlar\u0131 ve d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131nda \u00e7al\u0131\u015fma y\u00fcr\u00fcten sa\u011fl\u0131k personeli, ge\u00e7en ay ortaya \u00e7\u0131kan bir vir\u00fcs\u00fcn neden oldu\u011fu hastal\u0131k nedeniyle olduk\u00e7a endi\u015feli. \u015eiddetli solunum yolu yetersizli\u011fine neden olan bu vir\u00fcs\u00fcn zamanla yay\u0131l\u0131yor olmas\u0131 endi\u015felerin b\u00fcy\u00fcmesine neden oluyor. Peki bu salg\u0131n d\u00fcnya geneline yay\u0131lacak m\u0131? Bu hastal\u0131\u011f\u0131n kayna\u011f\u0131 ne? Tedavi metotlar\u0131 var m\u0131? 10 soru ve […]<\/p>\n","protected":false},"author":1390,"featured_media":39835,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[609,5765,5763,5764,492,5762],"class_list":["post-39831","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-cin","tag-karantina","tag-koronavirus","tag-salgin","tag-virus","tag-wuhan"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t