\u00c7in ve Almanya\u2019daki kurulu\u015flarla ba\u011flant\u0131l\u0131 bir ara\u015ft\u0131rma ekibi, kandaki y\u00fcksek glikoz seviyelerinin baz\u0131 grip hastalar\u0131nda neden daha \u015fiddetli semptomlar\u0131n g\u00f6r\u00fcld\u00fc\u011f\u00fcn\u00fc a\u00e7\u0131klayabilece\u011fini ortaya koydu.<\/p>\n
Science Advances<\/em> dergisinde yay\u0131mlanan makalede, fare modelleri ve grip hastalar\u0131 ile yap\u0131lan \u00e7al\u0131\u015fman\u0131n \u00e7\u0131kt\u0131lar\u0131na yer verildi.<\/p>\n Koronavir\u00fcs k\u00fcresel salg\u0131n\u0131 s\u00fcrecinde sa\u011fl\u0131k \u00e7al\u0131\u015fanlar\u0131 ve ara\u015ft\u0131rmac\u0131lar diyabet hastalar\u0131n\u0131n altta yatan bir hastal\u0131\u011f\u0131 olmayan ki\u015filere k\u0131yasla daha k\u00f6t\u00fc neticelere sahip olduklar\u0131n\u0131 belirttiler. Ayn\u0131 durum grip enfeksiyonu ta\u015f\u0131yan ki\u015filer i\u00e7in de ge\u00e7erlidir. Yeni \u00e7al\u0131\u015fmada ise, ara\u015ft\u0131rmac\u0131lar bu t\u00fcr hastal\u0131klara sahip olan ki\u015filerin, zat\u00fcrre ve \u00f6l\u00fcme yol a\u00e7abilecek bir yang\u0131sal yan\u0131ta neden daha duyarl\u0131 olduklar\u0131n\u0131 anlamaya \u00e7al\u0131\u015ft\u0131lar.<\/p>\n Daha \u00f6nce yap\u0131lan \u00e7al\u0131\u015fmalara g\u00f6re, grip etmeni olan Influenza vir\u00fcs\u00fc (veya SARS-CoV-2) insan v\u00fccuduna giri\u015f yapt\u0131\u011f\u0131nda ba\u011f\u0131\u015f\u0131kl\u0131k sistemi, tehdide kar\u015f\u0131 sava\u015fmak i\u00e7in enfeksiyonun ba\u015flad\u0131\u011f\u0131 b\u00f6lgeye ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri g\u00f6ndererek yan\u0131t \u00fcretir. Sitokinler de bu yan\u0131t\u0131n bir par\u00e7as\u0131 olarak \u00fcretilirler, sitokinlerin g\u00f6revi h\u00fccreler aras\u0131 ileti\u015fimi kontrol alt\u0131nda tutmakt\u0131r. Bununla beraber, baz\u0131 insanlarda v\u00fccutta \u00e7ok fazla sitokin \u00fcretimi olur ve sitokin f\u0131rt\u0131nas\u0131 ad\u0131 verilen durum ya\u015fan\u0131r. Sitokin f\u0131rt\u0131nas\u0131, zat\u00fcrre ve \u00f6l\u00fcm gibi \u00e7ok ciddi sa\u011fl\u0131k sorunlar\u0131na yol a\u00e7abilir.<\/p>\n Biliminsanlar\u0131, sitokin f\u0131rt\u0131nas\u0131n\u0131n neden baz\u0131 hastalarda ortaya \u00e7\u0131karken di\u011fer hastalarda g\u00f6r\u00fclmedi\u011fini hen\u00fcz bilmiyorlar. S\u00f6z konusu yeni \u00e7al\u0131\u015fmada yer alan ara\u015ft\u0131rmac\u0131lar sitokin f\u0131rt\u0131nas\u0131nda kan dola\u015f\u0131m\u0131ndaki y\u00fcksek glikoz d\u00fczeylerinin rol oynayabilece\u011finden \u015f\u00fcphelendi. Grip etmeni Influenza vir\u00fcs\u00fcn\u00fcn enfekte etti\u011fi bir grup farede, y\u00fcksek glikoz oran\u0131n\u0131n sitokin f\u0131rt\u0131nas\u0131na etki edip etmeyece\u011fini g\u00f6rmek i\u00e7in deney yap\u0131ld\u0131.<\/p>\n \u00c7al\u0131\u015fman\u0131n bir di\u011fer k\u0131sm\u0131, k\u00fcresel salg\u0131n \u00f6ncesinde \u00c7in\u2019in Wuhan kentinde bulunan iki hastanedeki 119 grip hastas\u0131ndan al\u0131nan kan \u00f6rneklerinin analiz edilmesini kaps\u0131yordu. Ara\u015ft\u0131rmac\u0131lar, normal kan \u00f6rneklerinden elde edilen sonu\u00e7lar ile bulgular\u0131n\u0131 kar\u015f\u0131la\u015ft\u0131rd\u0131. Daha y\u00fcksek glikoz seviyesine sahip hastalar\u0131n sitokin f\u0131rt\u0131nas\u0131 ya\u015fama olas\u0131l\u0131\u011f\u0131n\u0131n daha y\u00fcksek olabilece\u011fine i\u015faret eden sonu\u00e7lara ula\u015ft\u0131lar. S\u00f6z konusu \u00e7al\u0131\u015fma, diyabet hastalar\u0131n\u0131n sitokin f\u0131rt\u0131nas\u0131 ya\u015fama ve grip enfeksiyonlar\u0131nda hastal\u0131\u011f\u0131n daha a\u011f\u0131r bir seyir izlemesi gibi durumlar\u0131 ya\u015fama ihtimallerinin daha y\u00fcksek oldu\u011funu g\u00f6steriyor. Biliminsanlar\u0131 bu durumun COVID-19 i\u00e7in de ge\u00e7erli olabilece\u011fi g\u00f6r\u00fc\u015f\u00fcnde.<\/p>\n Kaynak:<\/strong> https:\/\/medicalxpress.com\/news\/2020-04-high-glucose-flu-patients-severe.html<\/p>\n","protected":false},"excerpt":{"rendered":" \u00c7in ve Almanya\u2019daki kurulu\u015flarla ba\u011flant\u0131l\u0131 bir ara\u015ft\u0131rma ekibi, kandaki y\u00fcksek glikoz seviyelerinin baz\u0131 grip hastalar\u0131nda neden daha \u015fiddetli semptomlar\u0131n g\u00f6r\u00fcld\u00fc\u011f\u00fcn\u00fc a\u00e7\u0131klayabilece\u011fini ortaya koydu. Science Advances dergisinde yay\u0131mlanan makalede, fare modelleri ve grip hastalar\u0131 ile yap\u0131lan \u00e7al\u0131\u015fman\u0131n \u00e7\u0131kt\u0131lar\u0131na yer verildi. Koronavir\u00fcs k\u00fcresel salg\u0131n\u0131 s\u00fcrecinde sa\u011fl\u0131k \u00e7al\u0131\u015fanlar\u0131 ve ara\u015ft\u0131rmac\u0131lar diyabet hastalar\u0131n\u0131n altta yatan bir hastal\u0131\u011f\u0131 olmayan ki\u015filere […]<\/p>\n","protected":false},"author":1390,"featured_media":42974,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[6356,5851,6357,6292,492],"class_list":["post-42973","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-glikoz","tag-influenza","tag-kan-dolasimi","tag-sitokin-firtinasi","tag-virus"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t