{"id":44725,"date":"2020-06-07T11:00:39","date_gmt":"2020-06-07T08:00:39","guid":{"rendered":"https:\/\/bilimvegelecek.com.tr\/?p=44725"},"modified":"2020-06-08T12:06:18","modified_gmt":"2020-06-08T09:06:18","slug":"solucanlar-kolonilerine-fayda-saglamak-icin-yasamin-erken-evrelerinde-oluyor","status":"publish","type":"post","link":"https:\/\/bilimvegelecek.com.tr\/index.php\/2020\/06\/07\/solucanlar-kolonilerine-fayda-saglamak-icin-yasamin-erken-evrelerinde-oluyor","title":{"rendered":"Solucanlar, kendilerini ya\u015fam\u0131n erken evrelerinde \u00f6l\u00fcme programlayabiliyor"},"content":{"rendered":"

\u0130ngiltere\u2019den ara\u015ft\u0131rmac\u0131lar genetik yap\u0131s\u0131 ya\u015fl\u0131l\u0131\u011fa ula\u015fmadan \u00f6nce \u00f6lmeye yatk\u0131n olan solucanlar ke\u015ffettiklerini ve solucanlardaki bu mekanizman\u0131n g\u0131da talebini azaltarak koloniye fayda sa\u011flamak amac\u0131yla i\u015fledi\u011fini a\u00e7\u0131klad\u0131. Bu durum, toplulu\u011fun yarar\u0131n\u0131 \u00f6nceleyerek evrimle\u015fen bir hayvanda programlanm\u0131\u015f \u00f6l\u00fcm\u00fcn ilk kan\u0131t\u0131d\u0131r.<\/p>\n

Aging Cell<\/em> portal\u0131nda yay\u0131nlanan \u00e7al\u0131\u015fmada Caenorhabditis elegans<\/em> t\u00fcr\u00fc solucanlara odaklan\u0131ld\u0131. Makalenin ba\u015fyazar\u0131 Evgeniy Galimov, \u201cProgramlanm\u0131\u015f h\u00fccre \u00f6l\u00fcm\u00fcn\u00fcn canl\u0131 organizmalara fayda sa\u011flad\u0131\u011f\u0131n\u0131 y\u0131llard\u0131r biliyoruz. Ancak art\u0131k hayvan kolonilerine fayda sa\u011flayabilecek programlanm\u0131\u015f \u00f6l\u00fcm\u00fcn organizma d\u00fczeyinde de oldu\u011funun fark\u0131nday\u0131z\u201d a\u00e7\u0131klamalar\u0131nda bulundu. Ara\u015ft\u0131rmac\u0131lar s\u00f6z konusu durumun, ya\u015fam d\u00f6ng\u00fcleri b\u00f6ylesi bir mekanizma i\u00e7in uygun olan solucanlara \u00f6zg\u00fc oldu\u011funu ifade ediyor.<\/p>\n

Bununla beraber, bu ara\u015ft\u0131rman\u0131n C. elegans<\/em> kullan\u0131larak y\u00fcr\u00fct\u00fclen ya\u015flanma biyolojisi \u00e7al\u0131\u015fmalar\u0131 i\u00e7in b\u00fcy\u00fck etkilerinin olaca\u011f\u0131 ileri s\u00fcr\u00fclmektedir. Di\u011fer hayvanlarda da ya\u015fam\u0131n ge\u00e7 d\u00f6nemlerinde g\u00f6r\u00fclen hastal\u0131klar\u0131n geli\u015fimini te\u015fvik eden, solucanlarda ya\u015fam s\u00fcresini k\u0131saltan benzer genler bulundu\u011fu ifade edilmektedir.<\/p>\n

Ya\u015flanman\u0131n, topluluk i\u00e7indeki gen\u00e7 bireylerin g\u0131daya ula\u015f\u0131m\u0131n\u0131 artt\u0131rmak amac\u0131yla n\u00fcfusun azalt\u0131lmas\u0131 i\u00e7in evrimle\u015fti\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyordu. Ancak biliminsanlar\u0131 bu durumun \u00e7o\u011fu hayvan t\u00fcr\u00fc i\u00e7in ge\u00e7erli olmad\u0131\u011f\u0131n\u0131 g\u00f6sterdi. Bununla beraber baz\u0131 organizmalar kendi kendini yok edebilen mekanizmalara sahiptir. B\u00f6ylesi mekanizmalar t\u00fcrlerin belirli bir ya\u015f\u0131n \u00f6tesinde ya\u015famalar\u0131n\u0131 \u00f6nler. Bu mekanizmalar\u0131n i\u015flevsizle\u015fmesi ise ya\u015fam s\u00fcresinin uzamas\u0131n\u0131 sa\u011flayabilir. \u00d6rne\u011fin, C. elegans<\/em> genomundaki belirli genlerde ger\u00e7ekle\u015fen mutasyonlar, ya\u015fam\u0131 k\u0131saltan mekanizmalar\u0131n i\u015flevsizle\u015fmesini sa\u011flayarak \u00f6mr\u00fc uzatabilir.<\/p>\n

Yap\u0131lan son ara\u015ft\u0131rmada, s\u0131n\u0131rland\u0131r\u0131lm\u0131\u015f bir g\u0131da tedari\u011finin bulundu\u011fu ortamda b\u00fcy\u00fcyen bir C. elegans<\/em> kolonisinin bilgisayar modellemesi geli\u015ftirildi ve daha k\u0131sa ya\u015fam s\u00fcrelerinin koloninin \u00fcreme kapasitesini art\u0131r\u0131p art\u0131rmayaca\u011f\u0131 test edildi. Ara\u015ft\u0131rmac\u0131lar, daha k\u0131sa bir ya\u015fam s\u00fcresi, daha k\u0131sa \u00fcreme s\u00fcresi ve yeti\u015fkin bireylerin beslenme oran\u0131n\u0131n azalmas\u0131 gibi durumlar\u0131n koloninin \u00fcreme ba\u015far\u0131s\u0131n\u0131 art\u0131rd\u0131\u011f\u0131n\u0131 buldular.<\/p>\n

Biliminsanlar\u0131, bir sonraki a\u015famada, ger\u00e7ek C. elegans<\/em> kolonilerini inceleyerek programlanabilir \u00f6l\u00fcm\u00fc daha iyi anlayabilmek i\u00e7in daha ger\u00e7ek\u00e7i modeller kullan\u0131labilece\u011fini ifade ediyor.<\/p>\n

Kaynak:<\/strong> https:\/\/cosmosmagazine.com\/biology\/researchers-find-worms-programmed-to-die-early\/<\/p>\n","protected":false},"excerpt":{"rendered":"

\u0130ngiltere\u2019den ara\u015ft\u0131rmac\u0131lar genetik yap\u0131s\u0131 ya\u015fl\u0131l\u0131\u011fa ula\u015fmadan \u00f6nce \u00f6lmeye yatk\u0131n olan solucanlar ke\u015ffettiklerini ve solucanlardaki bu mekanizman\u0131n g\u0131da talebini azaltarak koloniye fayda sa\u011flamak amac\u0131yla i\u015fledi\u011fini a\u00e7\u0131klad\u0131. Bu durum, toplulu\u011fun yarar\u0131n\u0131 \u00f6nceleyerek evrimle\u015fen bir hayvanda programlanm\u0131\u015f \u00f6l\u00fcm\u00fcn ilk kan\u0131t\u0131d\u0131r. Aging Cell portal\u0131nda yay\u0131nlanan \u00e7al\u0131\u015fmada Caenorhabditis elegans t\u00fcr\u00fc solucanlara odaklan\u0131ld\u0131. Makalenin ba\u015fyazar\u0131 Evgeniy Galimov, \u201cProgramlanm\u0131\u015f h\u00fccre \u00f6l\u00fcm\u00fcn\u00fcn canl\u0131 […]<\/p>\n","protected":false},"author":1390,"featured_media":44726,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[6797,6798,5302,595,6799],"class_list":["post-44725","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-koloni","tag-programlanmis-olum","tag-solucan","tag-yasam","tag-yaslanma-biyolojisi"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t