{"id":48623,"date":"2010-09-01T12:19:38","date_gmt":"2010-09-01T09:19:38","guid":{"rendered":"https:\/\/bilimvegelecek.com.tr\/?p=48623"},"modified":"2021-02-05T12:26:29","modified_gmt":"2021-02-05T09:26:29","slug":"kanserin-yayilma-potansiyelini-tespit-eden-kromozomal-test-bulundu","status":"publish","type":"post","link":"https:\/\/bilimvegelecek.com.tr\/index.php\/2010\/09\/01\/kanserin-yayilma-potansiyelini-tespit-eden-kromozomal-test-bulundu","title":{"rendered":"Kanserin yay\u0131lma potansiyelini tespit eden kromozomal test bulundu!"},"content":{"rendered":"

Ok\u00fcler melanom ya da di\u011fer ad\u0131yla \u201cG\u00f6z Kanseri\u201d Amerika\u2019da her y\u0131l 2000 ki\u015fide tespit edilen ciddi bir hastal\u0131k. Nadir g\u00f6r\u00fclen bu hastal\u0131k en agresif kanser tiplerinden biri. Ok\u00fcler melanom hastalar\u0131n\u0131n yakla\u015f\u0131k yar\u0131s\u0131 hayat\u0131n\u0131 kaybediyor. Metastaz g\u00f6steren melanom alt tipine sahip hastalar, genelde yaln\u0131zca 6 ile 12 ay aras\u0131nda ya\u015fayabiliyor. \u00c7\u00fcnk\u00fc t\u00fcm\u00f6r h\u00fccreleri v\u00fccudun di\u011fer b\u00f6lgelerine g\u00f6\u00e7 ederek orada yeni agresif kanser t\u00fcrlerine neden oluyor.<\/p>\n

Bu kanser t\u00fcr\u00fcne yakalanan avukat Susan Izanstark-Rosenthal i\u015fi gere\u011fi her an okumak ve yazmak zorunda oldu\u011funu ve g\u00f6zlerini kaybetmenin onun i\u00e7in ya\u015fam\u0131n\u0131 b\u00fcy\u00fck \u00f6l\u00e7\u00fcde kaybetmek anlam\u0131na geldi\u011fini belirtiyor. Uygulanan cerrahi i\u015flem sonras\u0131 \u00e7\u0131kar\u0131lan t\u00fcm\u00f6r g\u00f6z\u00fcn kurtulmas\u0131n\u0131 sa\u011flam\u0131\u015f. Fakat t\u00fcm\u00f6r\u00fcn v\u00fccudun di\u011fer b\u00f6lgelerine yay\u0131l\u0131p yay\u0131lmayaca\u011f\u0131 hen\u00fcz bilinmiyordu. Ok\u00fcler onkolojist Tara Young, bu noktada Susan i\u00e7in umut \u0131\u015f\u0131\u011f\u0131 olmu\u015f ve yeni bir biyopsi y\u00f6ntemi ile t\u00fcm\u00f6r\u00fcn yay\u0131lma kapasitesinin \u015fimdiden anla\u015f\u0131labilece\u011fini ve k\u00f6t\u00fc bir durum i\u00e7in erken \u00f6nlemlerin al\u0131nabilece\u011fi m\u00fcjdesini vermi\u015f.<\/p>\n

UCLA \u00dcniversitesi G\u00f6z Enstit\u00fcs\u00fc gen\u00e7 ara\u015ft\u0131rmac\u0131s\u0131 Young\u2019a g\u00f6re, ok\u00fcler melanoma ile ilgili olarak hastal\u0131\u011f\u0131n ilk zamanlar\u0131ndan beri yap\u0131lan ara\u015ft\u0131rmalar\u0131n ba\u015f\u0131nda, bu tarz bir testin bulunabilirli\u011fi gelmekte. \u0130lk olarak uygulanan ve ba\u015far\u0131ya ula\u015fan bu y\u00f6ntem ile UCLA\u2019l\u0131 cerrahlar\u0131n ince bir i\u011fne ucu ile t\u00fcm\u00f6r h\u00fccrelerini saf bir \u015fekilde elde etmesinin ard\u0131ndan yap\u0131lan ara\u015ft\u0131rmalarda t\u00fcm\u00f6r\u00fcn yay\u0131lmas\u0131 ile ilgili olarak ilk ipu\u00e7lar\u0131 elde edilmeye ba\u015fland\u0131. Ultrafine ad\u0131 verilen biyopsi i\u011fneleri ile cerrahi i\u015flemden \u00f6nce \u00e7\u0131kar\u0131lan t\u00fcm\u00f6r h\u00fccreleri, h\u00fccre k\u00fclt\u00fcr\u00fc ortam\u0131nda \u00e7o\u011falt\u0131larak, genetik analizler yap\u0131l\u0131r hale getirildi. E\u011fer t\u00fcm\u00f6r h\u00fccreleri genomundaki kromozom 3\u2019\u00fcn bir kopyas\u0131 eksik ise kanserin yay\u0131lma riskinin de art\u0131\u015f g\u00f6sterdi\u011fi, kromozom 3\u2019\u00fcn yap\u0131s\u0131 ve say\u0131s\u0131 normal ise kanser yay\u0131l\u0131m\u0131 riskinin d\u00fc\u015ft\u00fc\u011f\u00fc tespit edildi. Bu analiz ile kromozom 3\u2019\u00fcn genetik bir belirte\u00e7 (marker) olarak kullan\u0131labilece\u011fi bulundu ve her bir hasta i\u00e7in t\u00fcm\u00f6r\u00fcn t\u00fcr\u00fcne g\u00f6re agresif tedavilerin uygulanabilirli\u011fi tespit edilebilir hale geldi.<\/p>\n

Susan\u2019\u0131n kromozom 3 yap\u0131s\u0131 ve kopya say\u0131s\u0131nda herhangi bir problem ile kar\u015f\u0131la\u015f\u0131lmam\u0131\u015f. Bu da hem Susan hem de k\u0131z karde\u015fi i\u00e7in endi\u015felerin giderilmesine ve ya\u015fan\u0131lacak her g\u00fcn\u00fcn ayr\u0131 bir \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131n\u0131n daha iyi anla\u015f\u0131lmas\u0131na neden olmu\u015f.<\/p>\n

Kaynak<\/strong>: http:\/\/www.sciencedaily.com\/videos\/2007\/0408-will_your_cancer_spread.htm – 21 A\u011fustos 2010<\/p>\n","protected":false},"excerpt":{"rendered":"

Ok\u00fcler melanom ya da di\u011fer ad\u0131yla \u201cG\u00f6z Kanseri\u201d Amerika\u2019da her y\u0131l 2000 ki\u015fide tespit edilen ciddi bir hastal\u0131k. Nadir g\u00f6r\u00fclen bu hastal\u0131k en agresif kanser tiplerinden biri. Ok\u00fcler melanom hastalar\u0131n\u0131n yakla\u015f\u0131k yar\u0131s\u0131 hayat\u0131n\u0131 kaybediyor. Metastaz g\u00f6steren melanom alt tipine sahip hastalar, genelde yaln\u0131zca 6 ile 12 ay aras\u0131nda ya\u015fayabiliyor. \u00c7\u00fcnk\u00fc t\u00fcm\u00f6r h\u00fccreleri v\u00fccudun di\u011fer b\u00f6lgelerine […]<\/p>\n","protected":false},"author":780,"featured_media":48624,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[116,38],"tags":[555,444,4717,7310,7311,425],"class_list":["post-48623","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-79-sayi","category-dergi-sayilari","tag-insan","tag-kanser","tag-metastaz","tag-okuler-melanom","tag-rosenthal","tag-saglik"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t