{"id":50285,"date":"2021-05-12T08:31:51","date_gmt":"2021-05-12T05:31:51","guid":{"rendered":"https:\/\/bilimvegelecek.com.tr\/?p=50285"},"modified":"2021-05-12T08:31:51","modified_gmt":"2021-05-12T05:31:51","slug":"beyincik-insan-beyninin-evriminde-onemli-bir-role-sahip-olabilir","status":"publish","type":"post","link":"https:\/\/bilimvegelecek.com.tr\/index.php\/2021\/05\/12\/beyincik-insan-beyninin-evriminde-onemli-bir-role-sahip-olabilir","title":{"rendered":"Beyincik, insan beyninin evriminde \u00f6nemli bir role sahip olabilir"},"content":{"rendered":"<p>Beyincik, sinir sisteminin hareketi koordine etmedeki rol\u00fc ile bilinen par\u00e7as\u0131d\u0131r. Yeni \u00e7al\u0131\u015fmaya g\u00f6re ise bu yap\u0131, evrimsel s\u00fcre\u00e7 i\u00e7erisinde insan k\u00fclt\u00fcr\u00fcne, diline ve alet kullan\u0131m\u0131na katk\u0131 sa\u011flayabilecek de\u011fi\u015fikliklere u\u011frad\u0131. Bu yeni bilgi, Duke \u00dcniversitesi&#8217;nden Elaine Guevara ve ekibinin <em>PLOS Genetics<\/em> dergisinde yay\u0131nlad\u0131klar\u0131 bir \u00e7al\u0131\u015fmadan elde edildi.<\/p>\n<p>\u0130nsanlar\u0131n d\u00fc\u015f\u00fcnme ve \u00f6\u011frenme kapasitesindeki art\u0131\u015f\u0131n nas\u0131l meydana geldi\u011fini ara\u015ft\u0131ran biliminsanlar\u0131, genellikle, beynin muhakeme ve karar verme gibi y\u00fcr\u00fctme i\u015flevleri i\u00e7in hayati \u00f6nem ta\u015f\u0131yan prefrontal kortekse odakland\u0131. Ancak son zamanlardaki \u00e7al\u0131\u015fmalar insan\u0131n bili\u015fsel yetilerinde rol\u00fc oldu\u011fu d\u00fc\u015f\u00fcn\u00fclen beyincik \u00fczerinde yo\u011funla\u015ft\u0131.<\/p>\n<p>Guevara ve ekibi, insanlar, \u015fempanzeler ve rhesus makak maymunlar\u0131 aras\u0131ndaki molek\u00fcler farkl\u0131l\u0131klar \u00fczerinden beyinci\u011fin ve prefrontal korteksin evrimini ara\u015ft\u0131rd\u0131. Ara\u015ft\u0131rmalar\u0131n\u0131 biraz daha geni\u015fleten biliminsanlar\u0131, bu t\u00fcrlerdeki de\u011fi\u015fimleri daha iyi anlayabilmek i\u00e7in epigenetik de\u011fi\u015fimlere odakland\u0131. \u00dc\u00e7 t\u00fcr\u00fcn beyin dokular\u0131ndan elde edilen genomlar incelendi, farkl\u0131l\u0131klar\u0131n temelini olu\u015fturan epigenetik de\u011fi\u015fimler analiz edildi. (Epigenetik, DNA dizisi \u00fczerinde de\u011fi\u015fim meydana getirmeden genin ifadesini de\u011fi\u015ftiren mekanizmalard\u0131r.)<\/p>\n<p>\u015eempanze ve makaklardaki versiyonlar\u0131 ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda insan beyinci\u011fi, prefrontal korteksten daha b\u00fcy\u00fck epigenetik farkl\u0131l\u0131klar g\u00f6stermekteydi. Bu durum insan beyninin evrimi a\u00e7\u0131s\u0131ndan beyinci\u011fin \u00f6nemli bir noktada durdu\u011funu g\u00f6stermekteydi. Epigenetik farkl\u0131l\u0131klar \u00f6zellikle de beyin geli\u015fimi, beyin iltihab\u0131, ya\u011f metabolizmas\u0131 ve sinaptik plastisite ile ilgili genlerde belirgindi. (Sinaptik plastisite, hangi s\u0131kl\u0131kta kullan\u0131ld\u0131klar\u0131na ba\u011fl\u0131 olarak n\u00f6ronlar aras\u0131ndaki ba\u011flant\u0131lar\u0131n g\u00fc\u00e7lenmesi veya zay\u0131flamas\u0131 durumudur.)<\/p>\n<p>Yeni \u00e7al\u0131\u015fman\u0131n i\u015faret etti\u011fi epigenetik farkl\u0131l\u0131klar, insan beyninin nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131, yeni ba\u011flant\u0131lar kurma ve adaptasyon yetene\u011fini anlamam\u0131za olanak tan\u0131maktad\u0131r. S\u00f6z konusu epigenetik farkl\u0131l\u0131klar ya\u015flanma ve hastal\u0131klar\u0131n ortaya \u00e7\u0131k\u0131\u015f\u0131nda da \u00e7e\u015fitli rollere sahip olabilir. Daha \u00f6nceki \u00e7al\u0131\u015fmalar insan ve \u015fempanze prefrontal korteksi aras\u0131ndaki epigenetik farkl\u0131l\u0131klar\u0131n, psikiyatrik durum ve n\u00f6rodejenerasyonla ilgili genlerle ili\u015fkili oldu\u011funu g\u00f6stermi\u015fti. Yeni \u00e7al\u0131\u015fma ise insan beyninin nas\u0131l evrimle\u015fti\u011fi incelenirken ara\u015ft\u0131rmalara beyinci\u011fin de dahil edilmesinin \u00f6nemine dikkat \u00e7ekmektedir.<\/p>\n<p><strong>Kaynak:<\/strong> <a href=\"https:\/\/www.sciencedaily.com\/releases\/2021\/05\/210506142039.htm\">SCIENCE DAILY<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Beyincik, sinir sisteminin hareketi koordine etmedeki rol\u00fc ile bilinen par\u00e7as\u0131d\u0131r. Yeni \u00e7al\u0131\u015fmaya g\u00f6re ise bu yap\u0131, evrimsel s\u00fcre\u00e7 i\u00e7erisinde insan k\u00fclt\u00fcr\u00fcne, diline ve alet kullan\u0131m\u0131na katk\u0131 sa\u011flayabilecek de\u011fi\u015fikliklere u\u011frad\u0131. Bu yeni bilgi, Duke \u00dcniversitesi&#8217;nden Elaine Guevara ve ekibinin PLOS Genetics dergisinde yay\u0131nlad\u0131klar\u0131 bir \u00e7al\u0131\u015fmadan elde edildi. \u0130nsanlar\u0131n d\u00fc\u015f\u00fcnme ve \u00f6\u011frenme kapasitesindeki art\u0131\u015f\u0131n nas\u0131l meydana geldi\u011fini [&hellip;]<\/p>\n","protected":false},"author":1390,"featured_media":50286,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19],"tags":[254,7688,2114,200,554],"class_list":["post-50285","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","tag-beyin","tag-beyincik","tag-epigenetik","tag-evrim","tag-sempanze"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"G\u00fclseli 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