{"id":55249,"date":"2022-07-13T17:21:06","date_gmt":"2022-07-13T14:21:06","guid":{"rendered":"https:\/\/bilimvegelecek.com.tr\/?p=55249"},"modified":"2022-07-24T21:13:19","modified_gmt":"2022-07-24T18:13:19","slug":"stres-bagisiklik-yaslanmasini-hizlandiriyor","status":"publish","type":"post","link":"https:\/\/bilimvegelecek.com.tr\/index.php\/2022\/07\/13\/stres-bagisiklik-yaslanmasini-hizlandiriyor","title":{"rendered":"Stres ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131n\u0131 h\u0131zland\u0131r\u0131yor"},"content":{"rendered":"

G\u00fcney Karolina \u00dcniversitesi(University of Southern Carolina; USC) biliminsanlar\u0131 taraf\u0131ndan yap\u0131lan bir ara\u015ft\u0131rmaya g\u00f6re g\u00f6re stres, -tramvatik olaylar, i\u015f y\u00fck\u00fc ve strese yol a\u00e7an g\u00fcnl\u00fck olaylar- ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin ya\u015flanmas\u0131n\u0131 h\u0131zland\u0131r\u0131yor; ki\u015finin kanser, dola\u015f\u0131m sistemi rahats\u0131zl\u0131klar\u0131 ile Kovid-19 gibi hastal\u0131klara yakalanmas\u0131 ve enfeksiyon riskini art\u0131r\u0131yor. 13 Haziran\u2019da Proceedings of the National Academy of Science (PNAS) <\/em>dergisinde\u00a0 yay\u0131mlanan bu ara\u015ft\u0131rma, ya\u015fa ba\u011fl\u0131 sa\u011fl\u0131kta farklar\u0131 a\u00e7\u0131klamaya yard\u0131mc\u0131 olabilir; pandemideki e\u015fitsizlik pay\u0131n\u0131 anlamak ve m\u00fcdahale i\u00e7in olas\u0131 meseleleri belirlemek de dahil.<\/p>\n

Ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131n\u0131 anlamak<\/strong>
\n\u201cD\u00fcnyan\u0131n ya\u015fl\u0131 pop\u00fclasyonu artt\u0131k\u00e7a, ya\u015f kaynakl\u0131 sa\u011fl\u0131kta farkl\u0131l\u0131klar\u0131 anlamak esas hale geliyor. Ba\u011f\u0131\u015f\u0131kl\u0131k sisteminde ya\u015f kaynakl\u0131 de\u011fi\u015fiklikler, giderek bozulan sa\u011fl\u0131kta kritik bir rol oynuyor\u201d, diyor USC Leanord Davis Ya\u015fl\u0131l\u0131k Bilimi Okulu\u2019ndan, doktora sonras\u0131 ara\u015ft\u0131rmac\u0131 Eric Klopack. \u201cBu ara\u015ft\u0131rma ba\u011f\u0131\u015f\u0131kl\u0131k sistemindeki h\u0131zlanm\u0131\u015f ya\u015flanmay\u0131 i\u00e7eren mekanizmalara a\u00e7\u0131kl\u0131k kazand\u0131r\u0131lmas\u0131na yard\u0131mc\u0131 oluyor.\u201d \u0130nsanlar ya\u015fland\u0131k\u00e7a, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi do\u011fal olarak dramatik bir d\u00fc\u015f\u00fc\u015fe ba\u015flar, bu duruma ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131<\/em> denir. \u0130lerleyen ya\u015fla ki\u015finin ba\u011f\u0131\u015f\u0131kl\u0131k profili zay\u0131flar; \u00e7ok fazla eskimi\u015f beyaz kan h\u00fccresi ve \u00e7ok az taze, i\u015fgalcilerle kar\u015f\u0131la\u015fmaya haz\u0131r, \u201c\u00e7aylak\u201d beyaz kan h\u00fccresi i\u00e7erir. Ba\u011f\u0131\u015f\u0131kl\u0131k sistemi ya\u015flanmas\u0131 sadece kanserle de\u011fil, dola\u015f\u0131m sistemi rahats\u0131zl\u0131klar\u0131, daha y\u00fcksek zat\u00fcrree riski, daha az etkili a\u015f\u0131lar ve organ ya\u015flanmas\u0131yla da ili\u015fkilendirilmektedir. Fakat, ayn\u0131 ya\u015ftaki yeti\u015fkinlerde ciddi sa\u011fl\u0131k farklar\u0131na ne sebep oluyor? USC ara\u015ft\u0131rmac\u0131lar\u0131 hayat boyunca strese maruz b\u0131rak\u0131lmayla -ki stresin zay\u0131f sa\u011fl\u0131\u011fa bilinen bir katk\u0131s\u0131 vard\u0131r- ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin g\u00fc\u00e7ten d\u00fc\u015fmesi aras\u0131nda ba\u011flant\u0131 olup olmad\u0131\u011f\u0131na bakmaya karar verdiler. Ekonomi, sa\u011fl\u0131k, evlilik ve aile durumu hakk\u0131ndaki ulusal bir \u00e7al\u0131\u015fma olan Michigan \u00dcniverstesi\u2019nin Sa\u011fl\u0131k ve Emeklilik \u00e7al\u0131\u015fmas\u0131nda, \u00e7ok b\u00fcy\u00fck veri k\u00fcmeleri sorguland\u0131 ve \u00e7arpraz olarak referansland\u0131.
\nAra\u015ft\u0131rmac\u0131lar, 50 ya\u015f\u0131n \u00fczerinde 5744 yeti\u015fkinden olu\u015fan ulusal bir \u00f6rnek grubundan gelen yan\u0131tlar\u0131, maruz kal\u0131nan \u00e7e\u015fitli sosyal stresleri \u00f6l\u00e7mek i\u00e7in analiz etti. Kat\u0131l\u0131mc\u0131lar, stresli ya\u015fam olaylar\u0131, kronik stres, g\u00fcndelik ayr\u0131mc\u0131l\u0131k ve ya\u015fam boyu ayr\u0131mc\u0131l\u0131k dahil sosyal stresle ilgili deneyimlerini \u00f6l\u00e7mek i\u00e7in tasarlanm\u0131\u015f bir anketi yan\u0131tlad\u0131lar. Daha sonra kat\u0131l\u0131mc\u0131lar\u0131n kan \u00f6rnekleri ak\u0131\u015f sitometrisiyle (ak\u0131\u015fl\u0131 h\u00fccre say\u0131m\u0131) analiz edildi; bu laboratuvar tekni\u011fi, kan h\u00fccreleri birer birer lazerin \u00f6n\u00fcnden ge\u00e7erken, onlar\u0131 say\u0131p, s\u0131n\u0131fland\u0131r\u0131r.
\nBeklendi\u011fi gibi, daha y\u00fcksek stres miktar\u0131 olan insanlar\u0131n, daha ya\u015fl\u0131 g\u00f6r\u00fcnen bir ba\u011f\u0131\u015f\u0131kl\u0131k profilleri vard\u0131; daha az taze hastal\u0131k sava\u015f\u00e7\u0131s\u0131 ve daha fazla eskimi\u015f beyaz kan h\u00fccresi i\u00e7eriyordu. Stresli hayat olaylar\u0131 ile daha az kar\u015f\u0131l\u0131k vermeye haz\u0131r, ya da toy T h\u00fccreleri aras\u0131ndaki ili\u015fki, e\u011fitim durumu, sigara i\u00e7mek, i\u00e7ki i\u00e7mek, \u0131rk ya da etnik k\u00f6ken kontrol edildikten sonra bile g\u00fc\u00e7l\u00fc kald\u0131. Baz\u0131 stres kaynaklar\u0131n\u0131 kontrol etmek m\u00fcmk\u00fcn olmasa da ara\u015ft\u0131rmac\u0131lar hayat\u0131m\u0131zdaki stres kaynaklar\u0131n\u0131 k\u0131s\u0131tlamak \u00fczerine orta yolun bulunmas\u0131n\u0131 tavsiye ediyor.<\/p>\n

“Stres ve ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131 aras\u0131ndaki ili\u015fkiyi tespit etmek zor de\u011fil”<\/strong>
\nBa\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n \u00e7ok \u00f6nemli bir par\u00e7as\u0131 olan T h\u00fccreleri, kalbin hemen \u00fcst\u00fcnde duran tim\u00fcs denilen bir bezde geli\u015fir. Ya\u015f ilerledik\u00e7e tim\u00fcs dokusu k\u00fc\u00e7\u00fcl\u00fcr ve bu dokunun yerini ya\u011f h\u00fccreleri al\u0131r; bunun sonucunda da daha az say\u0131da ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccresi \u00fcretilir. Eski ara\u015ft\u0131rmalar, bu olay\u0131n sa\u011fl\u0131ks\u0131z diyet ve az egzersiz gibi stresle ili\u015fkilendirilen hayat tarzlar\u0131 taraf\u0131ndan h\u0131zland\u0131r\u0131ld\u0131\u011f\u0131n\u0131 savl\u0131yor.
\n\u201cBu ara\u015ft\u0131rmada, k\u00f6t\u00fc diyet ve az egzersiz istatistik olarak kontrol edildikten sonra, stres ve ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131n\u0131n h\u0131zlanmas\u0131 aras\u0131ndaki ba\u011flant\u0131 o kadar g\u00fc\u00e7l\u00fc de\u011fildi\u201d diyor Klopack. \u201cBunun anlam\u0131 daha fazla stres ya\u015fayan insanlar\u0131n daha k\u00f6t\u00fc beslenmeye ve daha az egzersiz yapmaya e\u011filim g\u00f6sterdikleridir; bu da neden h\u0131zl\u0131 ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131na sahip olduklar\u0131n\u0131 a\u00e7\u0131klar. Ya\u015fl\u0131 yeti\u015fkinlerde beslenme ve egzersiz davran\u0131\u015flar\u0131n\u0131 geli\u015ftirmek, stresle ba\u011flant\u0131l\u0131 ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131n\u0131 dengelemeye yard\u0131mc\u0131 olabilir. Ek olarak, sitomegalovir\u00fcs de (CMV) m\u00fcdahale i\u00e7in bir hedef olabilir. CMV insanlarda s\u0131k rastlanan, genelde asemptomatik bir vir\u00fcst\u00fcr ve ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131n\u0131 h\u0131zland\u0131rd\u0131\u011f\u0131 bilinir. Zona veya u\u00e7uk vir\u00fcs\u00fc gibi, CMV de genelde uykudad\u0131r, ama \u00f6zellikle ki\u015fi y\u00fcksek stres ya\u015f\u0131yorsa alevlenebilir.
\nBu \u00e7al\u0131\u015fmada, CMV pozitifli\u011finin istatistiksel olarak kontrol edilmesi, stres ile h\u0131zland\u0131r\u0131lm\u0131\u015f ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131 aras\u0131ndaki ba\u011flant\u0131y\u0131 da azaltt\u0131. Ara\u015ft\u0131rmac\u0131lar bu sebeple, yayg\u0131n CMV a\u015f\u0131lanmas\u0131 basit ve g\u00fc\u00e7l\u00fc bir m\u00fcdahale olabilir ve stresin ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131na etkisini azaltabilir diyorlar. Bu \u00e7al\u0131\u015fmada, CMV pozitifli\u011finin istatistiksel olarak kontrol edilmesi, stres ile h\u0131zland\u0131r\u0131lm\u0131\u015f ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131 aras\u0131ndaki ba\u011flant\u0131y\u0131 da azaltt\u0131. Ara\u015ft\u0131rmac\u0131lar bu sebeple, yayg\u0131n CMV a\u015f\u0131lanmas\u0131 basit ve g\u00fc\u00e7l\u00fc bir m\u00fcdahale olabilir ve stresin ba\u011f\u0131\u015f\u0131kl\u0131k ya\u015flanmas\u0131na etkisini azaltabilece\u011fini s\u00f6ylemekteler.<\/p>\n

Kaynak: Stress accelerates immune aging, study finds, Science Daily<\/a><\/strong><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

G\u00fcney Karolina \u00dcniversitesi(University of Southern Carolina; USC) biliminsanlar\u0131 taraf\u0131ndan yap\u0131lan bir ara\u015ft\u0131rmaya g\u00f6re g\u00f6re stres, -tramvatik olaylar, i\u015f y\u00fck\u00fc ve strese yol a\u00e7an g\u00fcnl\u00fck olaylar- ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin ya\u015flanmas\u0131n\u0131 h\u0131zland\u0131r\u0131yor; ki\u015finin kanser, dola\u015f\u0131m sistemi rahats\u0131zl\u0131klar\u0131 ile Kovid-19 gibi hastal\u0131klara yakalanmas\u0131 ve enfeksiyon riskini art\u0131r\u0131yor. 13 Haziran\u2019da Proceedings of the National Academy of Science (PNAS) dergisinde\u00a0 yay\u0131mlanan […]<\/p>\n","protected":false},"author":3699,"featured_media":55250,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19,21,4696],"tags":[1194,8487],"class_list":["post-55249","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","category-biyoloji","category-tip","tag-bagisiklik","tag-bagisiklik-yaslanmasi"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t