Yeni yay\u0131mlanan bu \u00e7al\u0131\u015fmada, Florida \u00dcniversitesi,\u00a0 Tar\u0131msal Ara\u015ft\u0131rma Servisi -USDA, Louisiana Eyalet \u00dcniversitesi ve Nebraska-Lincoln \u00dcniversitesi’nden entomologlar\u0131(b\u00f6cek bilimci) i\u00e7eren ara\u015ft\u0131rma ekibi, bal ar\u0131lar\u0131n\u0131n h\u00fccrelerinin serbest radikal \u00fcretmesini sa\u011flaman\u0131n ar\u0131lar\u0131n bir dizi vir\u00fcs\u00fc uzakla\u015ft\u0131rmas\u0131na yard\u0131mc\u0131 oldu\u011funu g\u00f6sterdi. Bu tedavi, vir\u00fcs aktivitesini neredeyse tamamen ortadan kald\u0131rm\u0131\u015ft\u0131.
\n\u00c7al\u0131\u015fman\u0131n k\u0131demli yazar\u0131 Daniel Swale, “Bu yakla\u015f\u0131m \u00f6zellikle heyecan verici \u00e7\u00fcnk\u00fc yaln\u0131zca belirli bir vir\u00fcs t\u00fcr\u00fcn\u00fc hedeflemiyor, ayn\u0131 zamanda bir\u00e7ok farkl\u0131 vir\u00fcs\u00fcn savu\u015fturulmas\u0131na da yard\u0131mc\u0131 oluyor. Ek olarak, tedavimizin hem laboratuvarda hem de tarlada her biri 80.000 ar\u0131 i\u00e7eren kolonilerde \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131 g\u00f6sterdik. Bu \u00e7ok b\u00fcy\u00fck \u00e7\u00fcnk\u00fc kovan ortam\u0131nda ar\u0131lar \u00e7ok farkl\u0131 vir\u00fcslere ve stres\u00f6rlere maruz kal\u0131yor, bu nedenle o ortamdaki vir\u00fcsleri ba\u015far\u0131l\u0131 bir \u015fekilde kontrol etmek \u00e7ok cesaret verici “diyor.
\nBal ar\u0131s\u0131 kolonileri ve onlar\u0131 y\u00f6neten ar\u0131c\u0131lar, bir\u00e7ok mahsul\u00fc tozla\u015ft\u0131rarak g\u0131da \u00fcretiminde \u00f6nemli bir rol oynamaktad\u0131r. Son y\u0131llarda, bal ar\u0131s\u0131 pop\u00fclasyonlar\u0131nda \u00f6nemli d\u00fc\u015f\u00fc\u015fler g\u00f6r\u00fclm\u00fc\u015ft\u00fcr ve vir\u00fcsler, bal ar\u0131s\u0131 \u00f6l\u00fcmlerinin en \u00f6nemli nedeni olmasa da ba\u015fl\u0131ca katk\u0131da bulunanlar aras\u0131ndad\u0131rlar.
\n\u00c7al\u0131\u015fman\u0131n ortak yazar\u0131 ve Louisiana’daki Baton Rouge’daki ARS Bal Ar\u0131s\u0131 Yeti\u015ftiricili\u011fi, Genetik ve Fizyoloji Ara\u015ft\u0131rma Laboratuvar\u0131 ile molek\u00fcler biyolog olan Michael Simone-Finstrom;”Varroa akarlar\u0131 bal ar\u0131s\u0131 kay\u0131plar\u0131n\u0131n bir numaral\u0131 nedenidir, ancak varroa akarlar\u0131n\u0131n ar\u0131lar\u0131 fiziksel olarak zay\u0131flatman\u0131n yan\u0131 s\u0131ra vir\u00fcsleri ar\u0131lara da bula\u015ft\u0131rd\u0131\u011f\u0131n\u0131 belirtmek \u00f6nemlidir. Bal ar\u0131s\u0131 kolonilerindeki vir\u00fcsleri azaltabilirsek, bu ileriye do\u011fru b\u00fcy\u00fck bir ad\u0131m olacakt\u0131r” diyor.<\/p>\n
Deneyde ara\u015ft\u0131rmac\u0131lar, ar\u0131lar\u0131n ve \u00e7o\u011fu canl\u0131n\u0131n h\u00fccrelerinde bulunan bir protein olan potasyum iyon kanallar\u0131n\u0131 de\u011fi\u015ftirmek i\u00e7in pinasidil ad\u0131 verilen bir bile\u015fik kulland\u0131lar. Bu kanallar\u0131n de\u011fi\u015ftirilmesi biraz daha fazla serbest radikal \u00fcretmektedir.
\nMakalenin ortak yazar\u0131 ve Nebraska-Lincoln \u00dcniversitesi’nde entomoloji profes\u00f6r\u00fc Troy Anderson; “Serbest radikaller genellikle h\u00fccre sa\u011fl\u0131\u011f\u0131 i\u00e7in k\u00f6t\u00fc olsa da bu \u00e7al\u0131\u015fmada g\u00f6rd\u00fc\u011f\u00fcm\u00fcz gibi \u0131l\u0131ml\u0131 miktarlarda terap\u00f6tik olabilirler. Bu durumda, ek serbest radikaller ba\u011f\u0131\u015f\u0131kl\u0131k sistemine y\u00fckselme sinyali verir, bu da ar\u0131lar\u0131n vir\u00fcslerle sava\u015fmas\u0131na yard\u0131mc\u0131 olur\u201d diyor.
\nBilim insanlar\u0131 ilac\u0131 bal ar\u0131s\u0131 kolonilerine \u015fekerli suya kar\u0131\u015ft\u0131rarak ve suyu gece bal tara\u011f\u0131n\u0131n \u00fczerine gezdirerek uygulad\u0131lar. Ar\u0131lar daha sonra \u015fekerli suyu t\u00fcketip yavrular\u0131na beslediler. G\u00fcn boyunca ar\u0131lar s\u00fcrekli olarak kovandan d\u0131\u015far\u0131 do\u011fru hareket ederler, bu nedenle onlara geceleri tedavi vermek, bundan yararlanacak ar\u0131 say\u0131s\u0131n\u0131 en \u00fcst d\u00fczeye \u00e7\u0131kar\u0131r.
\nTedavi, ar\u0131lar\u0131 potansiyel olarak \u00f6l\u00fcmc\u00fcl alt\u0131 bal ar\u0131s\u0131 vir\u00fcs\u00fcnden korumu\u015ftu: \u0130srail akut fel\u00e7 vir\u00fcs\u00fc, deforme olmu\u015f kanat vir\u00fcsleri A ve B, kara krali\u00e7e h\u00fccre vir\u00fcs\u00fc ve Sina G\u00f6l\u00fc vir\u00fcsleri 1 ve 2. Ara\u015ft\u0131rmac\u0131lar ayr\u0131ca pinasidilin, varroa akarlar\u0131yla yo\u011fun bir \u015fekilde istila edilmi\u015f kolonilerde daha fazla ar\u0131n\u0131n hayatta kalmas\u0131na yard\u0131mc\u0131 oldu\u011funu g\u00f6sterdi.
\nAra\u015ft\u0131rmac\u0131lar, pinasidilin ticari bal ar\u0131s\u0131 kovanlar\u0131na uygulanmas\u0131n\u0131n yaln\u0131zca baz\u0131 ar\u0131c\u0131lar i\u00e7in m\u00fcmk\u00fcn olabilece\u011fini, ancak \u00e7al\u0131\u015fman\u0131n daha iyi \u00e7al\u0131\u015fabilecek ve daha ucuza mal olabilecek di\u011fer aktif bile\u015fenleri belirlemeye kap\u0131 a\u00e7t\u0131\u011f\u0131n\u0131 s\u00f6ylediler.
\nSwale,”Bu \u00e7al\u0131\u015fman\u0131n en b\u00fcy\u00fck \u00e7\u0131kar\u0131mlar\u0131ndan biri, potasyum iyon kanallar\u0131n\u0131n bal ar\u0131lar\u0131nda ve muhtemelen di\u011fer b\u00f6ceklerde ba\u011f\u0131\u015f\u0131kl\u0131k sistemi i\u015flevini iyile\u015ftirmek i\u00e7in bir hedef olabilece\u011fidir. Peptit gibi bir molek\u00fcl veya pinasidil ile ayn\u0131 etkiye sahip ancak ar\u0131c\u0131lar i\u00e7in daha eri\u015filebilir olan yeni bir teknoloji bulmak istiyoruz “diyor.<\/p>\n","protected":false},"excerpt":{"rendered":"
Yeni yay\u0131mlanan bu \u00e7al\u0131\u015fmada, Florida \u00dcniversitesi,\u00a0 Tar\u0131msal Ara\u015ft\u0131rma Servisi -USDA, Louisiana Eyalet \u00dcniversitesi ve Nebraska-Lincoln \u00dcniversitesi’nden entomologlar\u0131(b\u00f6cek bilimci) i\u00e7eren ara\u015ft\u0131rma ekibi, bal ar\u0131lar\u0131n\u0131n h\u00fccrelerinin serbest radikal \u00fcretmesini sa\u011flaman\u0131n ar\u0131lar\u0131n bir dizi vir\u00fcs\u00fc uzakla\u015ft\u0131rmas\u0131na yard\u0131mc\u0131 oldu\u011funu g\u00f6sterdi. Bu tedavi, vir\u00fcs aktivitesini neredeyse tamamen ortadan kald\u0131rm\u0131\u015ft\u0131. \u00c7al\u0131\u015fman\u0131n k\u0131demli yazar\u0131 Daniel Swale, “Bu yakla\u015f\u0131m \u00f6zellikle heyecan verici \u00e7\u00fcnk\u00fc […]<\/p>\n","protected":false},"author":42,"featured_media":58836,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[19,4696],"tags":[2329,1194,2413,9041],"class_list":["post-58833","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim-gundemi","category-tip","tag-arilar","tag-bagisiklik","tag-bagisiklik-sistemi","tag-bal-arilari"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t